Pre_GI: BLASTP Hits

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Query: NC_012563:2680246:2690354 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2690354, End: 2691499, Length: 1146

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013941:3182576:3192521319252131938221302Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeBbp385e-43175
NC_010079:1564327:1597948159794815991141167Staphylococcus aureus subsp. aureus USA300_TCH1516, completehypothetical bacteriophage protein4e-87321
NC_013517:1480368:1487360148736014885291170Sebaldella termitidis ATCC 33386, complete genomehypothetical protein3e-74279
NC_014774:171500:2080092080092091751167Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completehypothetical protein6e-28125
NC_015590:1425628:1437780143778014390061227Sinorhizobium meliloti AK83 chromosome 1, complete sequencehypothetical protein1e-1790.9
NC_017297:2531750:2564841256484125659861146Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein0707
NC_017179:1683199:1691323169132316924891167Clostridium difficile BI1, complete genomehypothetical protein2e-104379
NC_014219:3254268:3259477325947732606431167Bacillus selenitireducens MLS10 chromosome, complete genomehypothetical protein6e-98357
NC_016077:1388775:1392353139235313934621110Acidaminococcus intestini RyC-MR95 chromosome, complete genomehypothetical protein2e-95349
NC_010320:1268355:1273383127338312745101128Thermoanaerobacter sp. X514 chromosome, complete genomehypothetical protein2e-88326
NC_007793:1574456:1584001158400115851671167Staphylococcus aureus subsp. aureus USA300, complete genomehypothetical protein4e-87321
NC_010337:2848360:2883029288302928841501122Heliobacterium modesticaldum Ice1, complete genomehypothetical protein5e-86318
NC_004668:295417:2961062961062972781173Enterococcus faecalis V583, complete genomehypothetical protein4e-85315
NC_017317:1291294:1311110131111013125911482Corynebacterium ulcerans 809 chromosome, complete genomehypothetical protein3e-82305
NC_011898:3367457:3411221341122134123571137Clostridium cellulolyticum H10, complete genomehypothetical protein7e-80297
NC_003909:386880:3937693937693948571089Bacillus cereus ATCC 10987, complete genomehypothetical protein5e-69261
NC_014774:1210004:1248881124888112500471167Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completehypothetical protein6e-29128
NC_012778:1573847:159476215947621595223462Eubacterium eligens ATCC 27750, complete genomehypothetical protein2e-23110
NC_014393:4775452:4820264482026448214061143Clostridium cellulovorans 743B chromosome, complete genomehypothetical protein2e-101369
NC_011660:2541632:2575705257570525768861182Listeria monocytogenes HCC23 chromosome, complete genomehypothetical protein2e-95349
NC_015520:2974048:3002935300293530040711137Mahella australiensis 50-1 BON chromosome, complete genomehypothetical protein5e-89328
NC_016791:4038069:4042587404258740437231137Clostridium sp. BNL1100 chromosome, complete genomehypothetical protein4e-86318
NC_004606:446427:4519414519414530981158Streptococcus pyogenes SSI-1, complete genomehypothetical protein4e-85315
NC_015683:1296000:1314737131473713162211485Corynebacterium ulcerans BR-AD22 chromosome, complete genomehypothetical protein6e-81301
NC_008530:1454118:1460826146082614619651140Lactobacillus gasseri ATCC 33323, complete genomehypothetical protein3e-71269
NC_012985:1191125:94894821141167Candidatus Liberibacter asiaticus str. psy62, complete genomehypothetical protein1e-27124
NC_015519:2526047:2536065253606525372251161Tepidanaerobacter sp. Re1 chromosome, complete genomehypothetical protein2e-122439
NC_014393:937000:9409219409219420871167Clostridium cellulovorans 743B chromosome, complete genomehypothetical protein2e-103375
NC_014219:3188128:3201079320107932023771299Bacillus selenitireducens MLS10 chromosome, complete genomehypothetical protein2e-96353
NC_013740:1218429:1224747122474712258951149Acidaminococcus fermentans DSM 20731, complete genomehypothetical protein1e-93343
NC_018704:1424728:1436429143642914375651137Amphibacillus xylanus NBRC 15112, complete genomehypothetical protein7e-91334
NC_017338:1517723:1551343155134315525091167Staphylococcus aureus subsp. aureus JKD6159 chromosome, completehypothetical protein4e-87321
NC_015558:905227:9195849195849207381155Streptococcus parauberis KCTC 11537 chromosome, complete genomehypothetical protein3e-86318
NC_009332:1050353:1063009106300910641661158Streptococcus pyogenes str. Manfredo chromosome, complete genomehypothetical protein1e-85317
NC_009633:4097536:4107168410716841083041137Alkaliphilus metalliredigens QYMF chromosome, complete genomehypothetical protein3e-81302
NC_016048:4047922:4071778407177840729621185Oscillibacter valericigenes Sjm18-20, complete genomehypothetical protein4e-61235
NC_012985:1:94894821141167Candidatus Liberibacter asiaticus str. psy62, complete genomehypothetical protein1e-27124
NC_012778:1573847:159554815955481595694147Eubacterium eligens ATCC 27750, complete genomehypothetical protein3e-0653.5
NC_009699:2552195:2564702256470225658471146Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein0707
NC_013315:1679000:1683308168330816844741167Clostridium difficile CD196 chromosome, complete genomehypothetical protein3e-104379
NC_002936:1004570:1004570100457010057091140Dehalococcoides ethenogenes 195, complete genomehypothetical protein3e-97355
NC_013740:1218429:1259651125965112607991149Acidaminococcus fermentans DSM 20731, complete genomehypothetical protein7e-95347
NC_007432:654904:6667276667276678481122Streptococcus agalactiae A909, complete genomehypothetical protein4e-91335
NC_016048:3947663:3951375395137539524871113Oscillibacter valericigenes Sjm18-20, complete genomehypothetical protein1e-87323
NC_016633:3069518:3115452311545231165761125Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomehypothetical protein1e-86320
NC_004070:1431146:1443787144378714449441158Streptococcus pyogenes MGAS315, complete genomehypothetical protein4e-85315
NC_014219:830966:8488878488878500141128Bacillus selenitireducens MLS10 chromosome, complete genomehypothetical protein4e-84311
NC_015697:506494:5119445119445130801137Lactobacillus reuteri SD2112 chromosome, complete genomephage protein8e-69261
NC_015913:117966:1212151212151223511137Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomephage protein6e-93341
NC_007297:1406796:1419343141934314204971155Streptococcus pyogenes MGAS5005, complete genomephage protein1e-83310
NC_017294:115500:1205321205321216681137Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomephage protein6e-93341
NC_012471:2080902:2098693209869320998501158Streptococcus equi subsp. equi 4047, complete genomephage protein1e-85317
NC_008023:1426687:1437686143768614388401155Streptococcus pyogenes MGAS2096, complete genomephage protein1e-83310
NC_008021:1401249:1413796141379614149501155Streptococcus pyogenes MGAS9429, complete genomephage protein1e-83310
NC_015697:468234:4709524709524720911140Lactobacillus reuteri SD2112 chromosome, complete genomephage protein2e-72273
NC_014246:1457992:1461045146104514621091065Mobiluncus curtisii ATCC 43063 chromosome, complete genomephage-associated protein7e-82304
NC_021064:793098:8127608127608139021143Propionibacterium avidum 44067, complete genomephage-associated protein2e-82306
NC_011375:749693:7553767553767565331158Streptococcus pyogenes NZ131 chromosome, complete genomephage-associated protein8e-86317
NC_014328:303063:3517023517023528651164Clostridium ljungdahlii ATCC 49587 chromosome, complete genomephage-like protein5e-83308
NC_021182:554000:5603115603115614921182Clostridium pasteurianum BC1, complete genomeProtein of unknown function (DUF2800)5e-85315
NC_017190:3166000:3175218317521831763961179Bacillus amyloliquefaciens LL3 chromosome, complete genomeprotein p515e-111401
NC_006086:35599:4111341113422701158Streptococcus pyogenes MGAS10394, complete genomeunknown phage protein4e-85315