Pre_GI: BLASTP Hits

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Query: NC_012563:2680246:2689722 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2689722, End: 2690342, Length: 621

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:2552195:256407025640702564624555Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein3e-83307
NC_015519:2526047:253553225355322536065534Tepidanaerobacter sp. Re1 chromosome, complete genomehypothetical protein2e-59228
NC_014393:937000:942089942089942628540Clostridium cellulovorans 743B chromosome, complete genomehypothetical protein3e-59228
NC_017190:3166000:317461231746123175187576Bacillus amyloliquefaciens LL3 chromosome, complete genomephage-associated protein9e-58223
NC_015697:506494:513061513061513636576Lactobacillus reuteri SD2112 chromosome, complete genomehypothetical protein9e-55213
NC_015913:117966:122367122367122927561Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomehypothetical protein5e-54210
NC_017294:115500:121684121684122244561Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomephage-associated protein6e-54210
NC_010320:1268355:127451612745161275076561Thermoanaerobacter sp. X514 chromosome, complete genomehypothetical protein1e-53209
NC_003909:386880:394909394909395457549Bacillus cereus ATCC 10987, complete genomehypothetical protein4e-53207
NC_008530:1454118:146192214619221462518597Lactobacillus gasseri ATCC 33323, complete genomehypothetical protein8e-53206
NC_011898:3367457:341066834106683411216549Clostridium cellulolyticum H10, complete genomehypothetical protein2e-52205
NC_015697:468234:472069472069472644576Lactobacillus reuteri SD2112 chromosome, complete genomephage-associated protein2e-52204
NC_014393:4775452:482139948213994821962564Clostridium cellulovorans 743B chromosome, complete genomehypothetical protein2e-51201
NC_009633:4097536:410661141066114107162552Alkaliphilus metalliredigens QYMF chromosome, complete genomehypothetical protein2e-51201
NC_016791:4038069:404203040420304042581552Clostridium sp. BNL1100 chromosome, complete genomehypothetical protein7e-51200
NC_018704:1424728:143587614358761436424549Amphibacillus xylanus NBRC 15112, complete genomehypothetical protein7e-51199
NC_010337:2848360:288416428841642884742579Heliobacterium modesticaldum Ice1, complete genomehypothetical protein4e-50197
NC_014328:303063:352843352843353391549Clostridium ljungdahlii ATCC 49587 chromosome, complete genomephage-like protein1e-49196
NC_002936:1004570:100400510040051004577573Dehalococcoides ethenogenes 195, complete genomehypothetical protein3e-49194
NC_016048:3947663:395079539507953951370576Oscillibacter valericigenes Sjm18-20, complete genomehypothetical protein5e-49193
NC_017179:1683199:169348716934871694059573Clostridium difficile BI1, complete genomehypothetical protein1e-48192
NC_013315:1679000:168547216854721686044573Clostridium difficile CD196 chromosome, complete genomehypothetical protein2e-48192
NC_014219:830966:850019850019850567549Bacillus selenitireducens MLS10 chromosome, complete genomehypothetical protein3e-48191
NC_014246:1457992:145999114599911460554564Mobiluncus curtisii ATCC 43063 chromosome, complete genomephage-associated protein2e-48191
NC_007432:654904:666159666159666722564Streptococcus agalactiae A909, complete genomehypothetical protein7e-48190
NC_013740:1218429:122418812241881224754567Acidaminococcus fermentans DSM 20731, complete genomehypothetical protein7e-48190
NC_015520:2974048:300236030023603002938579Mahella australiensis 50-1 BON chromosome, complete genomehypothetical protein1e-47189
NC_014219:3254268:325891632589163259464549Bacillus selenitireducens MLS10 chromosome, complete genomeAPSE-2 prophage; hypothetical7e-47186
NC_016077:1388775:139177313917731392339567Acidaminococcus intestini RyC-MR95 chromosome, complete genomehypothetical protein4e-46184
NC_016633:3069518:311488931148893115452564Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomehypothetical protein3e-46184
NC_012778:1573847:159569515956951596267573Eubacterium eligens ATCC 27750, complete genomehypothetical protein2e-45182
NC_017338:1517723:155076015507601551317558Staphylococcus aureus subsp. aureus JKD6159 chromosome, completephage protein9e-45179
NC_007793:1574456:158341815834181583975558Staphylococcus aureus subsp. aureus USA300, complete genomehypothetical protein9e-45179
NC_010079:1564327:159736515973651597922558Staphylococcus aureus subsp. aureus USA300_TCH1516, completehypothetical bacteriophage protein9e-45179
NC_021182:554000:561485561485562237753Clostridium pasteurianum BC1, complete genomeProtein of unknown function (DUF2815)4e-34144
NC_013740:1218429:125918012591801259635456Acidaminococcus fermentans DSM 20731, complete genomehypothetical protein3e-33141
NC_012471:2080902:209812120981212098678558Streptococcus equi subsp. equi 4047, complete genomephage protein5e-33140
NC_009332:1050353:106243710624371062994558Streptococcus pyogenes str. Manfredo chromosome, complete genomehypothetical protein5e-33140
NC_011375:749693:756548756548757105558Streptococcus pyogenes NZ131 chromosome, complete genomehypothetical protein5e-33140
NC_008023:1426687:143671614367161437273558Streptococcus pyogenes MGAS2096, complete genomephage protein4e-33140
NC_008021:1401249:141282614128261413383558Streptococcus pyogenes MGAS9429, complete genomephage protein4e-33140
NC_007297:1406796:141837314183731418930558Streptococcus pyogenes MGAS5005, complete genomephage protein4e-33140
NC_015558:905227:919008919008919571564Streptococcus parauberis KCTC 11537 chromosome, complete genomehypothetical protein1e-32139
NC_015683:1296000:131398913139891314606618Corynebacterium ulcerans BR-AD22 chromosome, complete genomehypothetical protein1e-32139
NC_017317:1291294:131036213103621310979618Corynebacterium ulcerans 809 chromosome, complete genomehypothetical protein1e-32139
NC_017297:2531750:256451825645182564829312Clostridium botulinum F str. 230613 chromosome, complete genome1e-31135
NC_006086:35599:422634226342847585Streptococcus pyogenes MGAS10394, complete genomeunknown phage protein2e-31135
NC_004606:446427:453091453091453675585Streptococcus pyogenes SSI-1, complete genomehypothetical protein2e-31135
NC_004070:1431146:144321014432101443773564Streptococcus pyogenes MGAS315, complete genomehypothetical protein2e-31135
NC_004668:295417:297898297898298473576Enterococcus faecalis V583, complete genomehypothetical protein4e-31134
NC_011660:2541632:257504025750402575621582Listeria monocytogenes HCC23 chromosome, complete genomehypothetical protein2e-30132
NC_013517:1480368:148854914885491489136588Sebaldella termitidis ATCC 33386, complete genomehypothetical protein4e-29127
NC_016048:4047922:407095440709544071760807Oscillibacter valericigenes Sjm18-20, complete genomehypothetical protein9e-26116
NC_021184:4524500:453124045312404531503264Desulfotomaculum gibsoniae DSM 7213, complete genome6e-23107
NC_013941:3182576:319383831938383194386549Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein3e-1478.6
NC_014774:1210004:125125412512541251805552Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completehypothetical protein1e-0653.1