Pre_GI: BLASTP Hits

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Query: NC_012563:2680246:2687749 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2687749, End: 2689716, Length: 1968

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:2552195:2561611256161125635871977Clostridium botulinum F str. Langeland chromosome, complete genomeDNA-directed DNA polymerase I01270
NC_017179:1683199:1694059169405916960171959Clostridium difficile BI1, complete genomedna-directed dna polymerase i0979
NC_013315:1679000:1686044168604416880021959Clostridium difficile CD196 chromosome, complete genomedna-directed dna polymerase i0974
NC_009253:1265474:1265474126547412674261953Desulfotomaculum reducens MI-1 chromosome, complete genomeDNA-directed DNA polymerase0813
NC_017190:3166000:3172057317205731740031947Bacillus amyloliquefaciens LL3 chromosome, complete genomeDNA-dependent DNA polymerase, family A0789
NC_015519:2526047:2533574253357425355321959Tepidanaerobacter sp. Re1 chromosome, complete genomeDNA-directed DNA polymerase0783
NC_014393:937000:9426419426419445781938Clostridium cellulovorans 743B chromosome, complete genomeDNA-directed DNA polymerase0765
NC_014219:3254268:3256965325696532589321968Bacillus selenitireducens MLS10 chromosome, complete genomeDNA-directed DNA polymerase0730
NC_010320:1268355:1275073127507312770071935Thermoanaerobacter sp. X514 chromosome, complete genomeDNA-directed DNA polymerase0729
NC_014219:830966:8505648505648524981935Bacillus selenitireducens MLS10 chromosome, complete genomeDNA-directed DNA polymerase0709
NC_015520:2974048:3000390300039030023631974Mahella australiensis 50-1 BON chromosome, complete genomeDNA-directed DNA polymerase0708
NC_014328:303063:3534693534693554181950Clostridium ljungdahlii ATCC 49587 chromosome, complete genomephage related DNA polymerase0702
NC_002936:67896:7099570995729351941Dehalococcoides ethenogenes 195, complete genomeDNA-dependent DNA polymerase, family A0683
NC_017294:115500:1222441222441241631920Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomeDNA-directed DNA polymerase0680
NC_015913:117966:1229271229271248461920Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomeDNA-directed DNA polymerase0679
NC_011898:3367457:3408136340813634100791944Clostridium cellulolyticum H10, complete genomeDNA-directed DNA polymerase0679
NC_003909:386880:3955303955303974641935Bacillus cereus ATCC 10987, complete genomeDNA polymerase I0677
NC_008530:1454118:1462573146257314645071935Lactobacillus gasseri ATCC 33323, complete genomeDNA polymerase I - 3'-5' exonuclease and polymerase domain0677
NC_009706:2673906:2732602273260227345361935Clostridium kluyveri DSM 555 chromosome, complete genomePhage-related DNA polymerase0677
NC_021182:554000:5622345622345642071974Clostridium pasteurianum BC1, complete genomeDNA polymerase I family protein with 3'-5'-exonuclease and polymerase domains0674
NC_010337:2848360:2884739288473928866791941Heliobacterium modesticaldum Ice1, complete genomeDNA polymerase i, putative0671
NC_017297:2531750:2562631256263125637251095Clostridium botulinum F str. 230613 chromosome, complete genome0669
NC_013740:1218429:1256938125693812589261989Acidaminococcus fermentans DSM 20731, complete genomeDNA-directed DNA polymerase0666
NC_015697:506494:5136925136925156261935Lactobacillus reuteri SD2112 chromosome, complete genomeprophage LambdaSa04 DNA-directed DNA polymerase0660
NC_016077:1388775:1389527138952713915241998Acidaminococcus intestini RyC-MR95 chromosome, complete genomeDNA polymerase I0659
NC_014393:4775452:4822059482205948240501992Clostridium cellulovorans 743B chromosome, complete genomeDNA-directed DNA polymerase0656
NC_015697:468234:4727004727004746341935Lactobacillus reuteri SD2112 chromosome, complete genomeprophage LambdaSa04 DNA-directed DNA polymerase0656
NC_016791:4038069:4039967403996740419551989Clostridium sp. BNL1100 chromosome, complete genomeDNA polymerase I family protein0650
NC_016633:3069518:3112861311286131148011941Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomeDNA polymerase I family protein0649
NC_015558:905227:9170439170439189651923Streptococcus parauberis KCTC 11537 chromosome, complete genomepolymerase0637
NC_004606:446427:4537184537184556401923Streptococcus pyogenes SSI-1, complete genomeputative DNA polymerase0636
NC_006086:35599:4289042890448121923Streptococcus pyogenes MGAS10394, complete genomephage-related DNA polymerase0636
NC_004070:1431146:1441245144124514431671923Streptococcus pyogenes MGAS315, complete genomeputative DNA polymerase A domain - phage associated0636
NC_008023:1426687:1434751143475114366731923Streptococcus pyogenes MGAS2096, complete genomephage-related DNA polymerase2e-180632
NC_007297:1406796:1416408141640814183301923Streptococcus pyogenes MGAS5005, complete genomephage-encoded DNA polymerase2e-180632
NC_008021:1401249:1410861141086114127831923Streptococcus pyogenes MGAS9429, complete genomephage-related DNA polymerase8e-180630
NC_017338:1517723:1548740154874015506921953Staphylococcus aureus subsp. aureus JKD6159 chromosome, completebacterophage DNA-directed DNA polymerase1e-179630
NC_010079:1564327:1595345159534515972971953Staphylococcus aureus subsp. aureus USA300_TCH1516, completebacterophage DNA-directed DNA polymerase1e-179630
NC_007793:1574456:1581398158139815833501953Staphylococcus aureus subsp. aureus USA300, complete genomephage related DNA polymerase, family A1e-179630
NC_012471:2080902:2096156209615620980781923Streptococcus equi subsp. equi 4047, complete genomephage DNA polymerase4e-179628
NC_009332:1050353:1060472106047210623941923Streptococcus pyogenes str. Manfredo chromosome, complete genomephage DNA polymerase3e-179628
NC_011375:749693:7571487571487590701923Streptococcus pyogenes NZ131 chromosome, complete genomeDNA polymerase3e-179628
NC_009633:4097536:4104091410409141060401950Alkaliphilus metalliredigens QYMF chromosome, complete genomeDNA-directed DNA polymerase3e-177622
NC_004668:295417:2992792992793012401962Enterococcus faecalis V583, complete genomeDNA polymerase, putative1e-172607
NC_014246:1457992:1457992145799214599681977Mobiluncus curtisii ATCC 43063 chromosome, complete genomeDNA-directed DNA polymerase1e-172606
NC_007432:654904:6639736639736659281956Streptococcus agalactiae A909, complete genomeprophage LambdaSa04, DNA polymerase8e-172604
NC_011660:2541632:2573109257310925747461638Listeria monocytogenes HCC23 chromosome, complete genomeDNA polymerase3e-171602
NC_016048:4047922:4068888406888840709062019Oscillibacter valericigenes Sjm18-20, complete genomeputative DNA polymerase1e-166587
NC_017317:1291294:1308287130828713102721986Corynebacterium ulcerans 809 chromosome, complete genomebacteriophage-type DNA polymerase2e-158559
NC_015683:1296000:1311914131191413138991986Corynebacterium ulcerans BR-AD22 chromosome, complete genomeDNA polymerase bacteriophage-type7e-158557
NC_018704:1424728:1434071143407114354951425Amphibacillus xylanus NBRC 15112, complete genomeDNA polymerase I1e-143510
NC_013740:1218429:1221209122120912241242916Acidaminococcus fermentans DSM 20731, complete genomeDNA-directed DNA polymerase3e-132472
NC_016048:3947663:3949211394921139504791269Oscillibacter valericigenes Sjm18-20, complete genomeputative DNA polymerase1e-108394
NC_013941:3182576:3195115319511531971782064Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeDNA polymerase I - 3''''-5'''' exonuclease and polymerase domains9e-105381
NC_012985:1191125:1191125119112511931522028Candidatus Liberibacter asiaticus str. psy62, complete genomeputative DNA polymerase from bacteriophage origin5e-97355
NC_014376:1842290:1854406185440618555441139Clostridium saccharolyticum WM1 chromosome, complete genome5e-95349
NC_014774:1210004:1251903125190312539302028Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completeputative DNA polymerase from bacteriophage origin4e-88326
NC_012985:1191125:3745374557722028Candidatus Liberibacter asiaticus str. psy62, complete genomeputative DNA polymerase from bacteriophage origin3e-85316
NC_012985:1:3745374557722028Candidatus Liberibacter asiaticus str. psy62, complete genomeputative DNA polymerase from bacteriophage origin3e-85316
NC_016048:3947663:394848539484853949204720Oscillibacter valericigenes Sjm18-20, complete genomeputative DNA polymerase7e-67255
NC_011138:831585:8361308361308372151086Alteromonas macleodii 'Deep ecotype', complete genomephage-related DNA polymerase4e-1893.6
NC_018704:1424728:143555914355591435801243Amphibacillus xylanus NBRC 15112, complete genomeDNA polymerase I2e-1791.7
NC_013124:1107202:1123306112330611259662661Acidimicrobium ferrooxidans DSM 10331, complete genomeDNA polymerase I8e-1582.8
NC_014010:1392536:1392536139253613954662931Candidatus Puniceispirillum marinum IMCC1322 chromosome, completeDNA polymerase I1e-1482.4
NC_008321:4631866:4655692465569246584602769Shewanella sp. MR-4, complete genomeDNA polymerase I4e-1480.5
NC_008577:4907497:4931315493131549340832769Shewanella sp. ANA-3 chromosome 1, complete sequenceDNA polymerase I4e-1480.1
NC_020126:2405175:2408242240824224103742133Myxococcus stipitatus DSM 14675, complete genomephage-related DNA polymerase5e-1480.1
NC_008261:2481500:2496982249698224995822601Clostridium perfringens ATCC 13124, complete genomeDNA polymerase I3e-1377.4
NC_011661:906583:9081099081099106762568Dictyoglomus turgidum DSM 6724, complete genomeDNA polymerase I4e-1377
NC_021064:816000:816318816318816509192Propionibacterium avidum 44067, complete genomebacteriophage-type DNA polymerase5e-1376.6
NC_008262:2150944:2166242216624221688422601Clostridium perfringens SM101, complete genomeDNA polymerase I9e-1375.9
NC_003366:2266757:2283149228314922857492601Clostridium perfringens str. 13, complete genomeDNA polymerase I1e-1275.1
NC_021182:2059143:2078590207859020812022613Clostridium pasteurianum BC1, complete genomeDNA polymerase I7e-1272.8
NC_008255:4208913:4221386422138642242262841Cytophaga hutchinsonii ATCC 33406, complete genomeDNA polymerase I1e-1172
NC_013171:1420135:1420135142013514227742640Anaerococcus prevotii DSM 20548, complete genomeDNA polymerase I2e-1171.2
NC_013170:917177:9373659373659400222658Cryptobacterium curtum DSM 15641, complete genomeDNA polymerase I5e-1170.1
NC_013009:608515:6085156085156109652451Neorickettsia risticii str. Illinois, complete genomeDNA polymerase I6e-1169.7
NC_016048:2678205:2678205267820526808592655Oscillibacter valericigenes Sjm18-20, complete genomeDNA polymerase I7e-1169.7
NC_006814:1538175:1538175153817515408472673Lactobacillus acidophilus NCFM, complete genomeDNA polymerase I2e-1068.6
NC_010725:2589014:2608552260855226116953144Methylobacterium populi BJ001, complete genomeDNA polymerase I1e-1068.6
NC_015696:610000:6141616141616168512691Francisella sp. TX077308 chromosome, complete genomeDNA polymerase I8e-1066.2
NC_015672:470000:4701754701754725562382Flexistipes sinusarabici DSM 4947 chromosome, complete genomeDNA polymerase I6e-0963.2
NC_015436:1322087:133637113363711336628258Spirochaeta coccoides DSM 17374 chromosome, complete genome2e-0861.2
NC_018704:1424728:143394314339431434140198Amphibacillus xylanus NBRC 15112, complete genomeDNA polymerase I1e-0758.9
NC_017208:1831918:1850299185029918527252427Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeDNA polymerase I3e-0757.4
NC_013939:1995546:1995546199554619979152370Deferribacter desulfuricans SSM1, complete genomeDNA polymerase I1e-0655.5
NC_004722:1804788:1819850181985018222582409Bacillus cereus ATCC 14579, complete genomeDNA polymerase I1e-0655.5
NC_012704:947409:9595609595609623372778Corynebacterium kroppenstedtii DSM 44385, complete genomeDNA polymerase I3e-0654.3
NC_012673:1:84768476110372562Exiguobacterium sp. AT1b, complete genomeDNA-directed DNA polymerase4e-0653.9