Pre_GI: BLASTP Hits

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Query: NC_012563:2680246:2680246 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2680246, End: 2680815, Length: 570

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2531750:255233525523352552922588Clostridium botulinum F str. 230613 chromosome, complete genomeputative phage terminase, small subunit4e-61233
NC_009699:2552195:255219525521952552782588Clostridium botulinum F str. Langeland chromosome, complete genomephage terminase small subunit4e-61233
NC_016935:6464201:647577064757706476294525Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein1e-1892.8
NC_015520:595532:601437601437601949513Mahella australiensis 50-1 BON chromosome, complete genomeTerminase small subunit2e-1685.5
NC_009012:2927793:294521629452162945665450Clostridium thermocellum ATCC 27405, complete genomeTerminase small subunit2e-1582.4
NC_009708:2537557:2541239254123925422551017Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein4e-1581.3
NC_009706:3341250:334260233426023343456855Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein5e-1580.9
NC_011837:3272752:327410432741043274958855Clostridium kluyveri NBRC 12016, complete genomehypothetical protein5e-1580.9
NC_011837:56000:579375793758518582Clostridium kluyveri NBRC 12016, complete genomehypothetical protein1e-1479.3
NC_011898:3567761:359745235974523597964513Clostridium cellulolyticum H10, complete genomeTerminase small subunit2e-1479
NC_009706:56000:579735797358518546Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein2e-1478.6
NC_011898:3824000:384587738458773846389513Clostridium cellulolyticum H10, complete genomeTerminase small subunit2e-1478.6
NC_020134:420500:432110432110432376267Clostridium stercorarium subsp. stercorarium DSM 8532, completeterminase small subunit1e-1272.8
NC_021182:2536000:255420825542082555176969Clostridium pasteurianum BC1, complete genomephage terminase, small subunit2e-1272
NC_008497:1111891:111633811163381117096759Lactobacillus brevis ATCC 367, complete genomehypothetical protein7e-1270.1
NC_014498:1983740:201399920139992014478480Streptococcus pneumoniae 670-6B chromosome, complete genomephage terminase small subunit6e-1167
NC_012466:1754388:176855317685531769053501Streptococcus pneumoniae JJA, complete genomephage terminase small subunit8e-1166.6
NC_009656:2422083:244101824410182441617600Pseudomonas aeruginosa PA7 chromosome, complete genometerminase small subunit1e-0962.8
NC_009778:2993218:300141130014113001968558Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein3e-0961.6
NC_012658:1810640:182776818277681828202435Clostridium botulinum Ba4 str. 657 chromosome, complete genomephage terminase small subunit9e-0960.1
NC_015425:1295261:130928913092891309750462Clostridium botulinum BKT015925 chromosome, complete genomephage terminase family protein1e-0859.3
UCMB5137:861734:861734861734862534801Bacillus atrophaeus UCMB-5137PBSX defective prophage terminase (small subunit)4e-0857.8
NC_012967:786534:791455791455792006552Escherichia coli B str. REL606 chromosome, complete genomehypothetical protein1e-0756.2
NC_013941:3182576:318420131842013184773573Escherichia coli O55:H7 str. CB9615 chromosome, complete genomephage terminase, small subunit2e-0755.5
NC_004557:1141558:115367911536791154602924Clostridium tetani E88, complete genomephage terminase small subunit1e-0653.1
NC_007712:2028500:204392120439212044445525Sodalis glossinidius str. 'morsitans', complete genomephage terminase small subunit5e-0650.8
NC_009674:2985878:300791230079123008343432Bacillus cytotoxicus NVH 391-98 chromosome, complete genometerminase small subunit7e-0650.4