Pre_GI: BLASTP Hits

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Query: NC_012563:2566500:2583760 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2583760, End: 2584374, Length: 615

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009495:2479465:249602524960252496639615Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein1e-80298
NC_011898:3567761:359143435914343592015582Clostridium cellulolyticum H10, complete genomeminor structural GP20 protein2e-1375.5
NC_015519:1081539:110206111020611102627567Tepidanaerobacter sp. Re1 chromosome, complete genomeminor structural GP20 protein1e-1169.7
NC_011898:3824000:383985938398593840440582Clostridium cellulolyticum H10, complete genomeminor structural GP20 protein2e-1375.9
NC_020134:420500:437505437505438083579Clostridium stercorarium subsp. stercorarium DSM 8532, completeminor structural GP20 protein6e-1270.9
NC_013517:1501276:150498315049831505585603Sebaldella termitidis ATCC 33386, complete genomeminor structural GP20 protein2e-1789
NC_017294:403422:413852413852414451600Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomeminor structural GP20 protein4e-1374.7
NC_009632:361229:382788382788383384597Staphylococcus aureus subsp. aureus JH1 chromosome, completephage minor structural GP203e-0858.5
NC_017341:1976000:199924419992441999840597Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,phage minor structural GP201e-0859.7
NC_009487:362475:382718382718383314597Staphylococcus aureus subsp. aureus JH9 chromosome, completephage minor structural GP203e-0858.5
NC_017297:2531750:254694125469412547546606Clostridium botulinum F str. 230613 chromosome, complete genomephage minor structural protein GP205e-1580.9
NC_021182:3347076:336061233606123361196585Clostridium pasteurianum BC1, complete genomePhage minor structural protein GP204e-1684.7
NC_021182:2536000:255982425598242560492669Clostridium pasteurianum BC1, complete genomePhage minor structural protein GP201e-0653.5
NC_021182:554000:577559577559578134576Clostridium pasteurianum BC1, complete genomePhage minor structural protein GP209e-1373.6
NC_008530:646207:661796661796662356561Lactobacillus gasseri ATCC 33323, complete genomePhage minor structural protein GP208e-0857
NC_017294:115500:137695137695138294600Candidatus Arthromitus sp. SFB-mouse-Yit, complete genomephage minor structural protein GP201e-1376.6
NC_015913:117966:138385138385138984600Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomephage scaffold protein1e-1376.6
NC_012658:2498087:251708825170882517702615Clostridium botulinum Ba4 str. 657 chromosome, complete genomephage scaffold protein4e-94343
NC_014328:3434478:345017834501783450849672Clostridium ljungdahlii ATCC 49587 chromosome, complete genomephage-like protein4e-30131
NC_012658:1810640:183329418332941833899606Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative scaffold protein2e-1685.5
NC_003212:57061:979339793398502570Listeria innocua Clip11262, complete genomeputative scaffolding protein [Bacteriophage A118]1e-0652.8
NC_003210:2380419:238041923804192381009591Listeria monocytogenes EGD-e, complete genomeputative scaffolding protein [Bacteriophage A118]2e-0962
NC_003210:2362306:238041923804192381009591Listeria monocytogenes EGD-e, complete genomeputative scaffolding protein [Bacteriophage A118]2e-0962
NC_014551:576000:600313600313600978666Bacillus amyloliquefaciens DSM 7, complete genomescaffold protein gp202e-1789