Pre_GI: BLASTP Hits

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Query: NC_012563:2566500:2578482 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2578482, End: 2579888, Length: 1407

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009633:2592000:2604136260413626055481413Alkaliphilus metalliredigens QYMF chromosome, complete genomehypothetical protein4e-147521
UCMB5137:861734:8690828690828704821401Bacillus atrophaeus UCMB-5137hypothetical protein1e-1378.6
NC_009848:2755874:2767729276772927690751347Bacillus pumilus SAFR-032, complete genomehypothetical protein1e-1791.3
NC_014976:627935:6646256646256660251401Bacillus subtilis BSn5 chromosome, complete genomehypothetical protein3e-20100
NC_016047:1435961:1437471143747114388711401Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completehypothetical protein5e-1376.3
NC_000964:2670288:267929726792972680214918Bacillus subtilis subsp. subtilis str. 168, complete genomehypothetical protein5e-1479.3
NC_000964:1330000:1331712133171213331061395Bacillus subtilis subsp. subtilis str. 168, complete genomehypothetical protein3e-1377
NC_017195:1308730:1309389130938913107891401Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completehypothetical protein2e-1274.3
NC_020244:1335531:1335531133553113369311401Bacillus subtilis XF-1, complete genomehypothetical protein2e-1273.9
NC_014652:801653:8190988190988205251428Caldicellulosiruptor hydrothermalis 108 chromosome, completehypothetical protein2e-31137
NC_015913:117966:1418151418151431161302Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomehypothetical protein7e-1375.5
NC_009617:1897887:1925941192594119273831443Clostridium beijerinckii NCIMB 8052 chromosome, complete genomehypothetical protein1e-148526
NC_009617:3926843:3946677394667739477981122Clostridium beijerinckii NCIMB 8052 chromosome, complete genomephage-like element pbsx protein XkdK2e-0757.8
NC_009495:2479465:2490476249047624918821407Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein0866
NC_010674:2817651:2836350283635028377651416Clostridium botulinum B str. Eklund 17B, complete genomehypothetical protein1e-130466
NC_010723:915697:9222199222199235291311Clostridium botulinum E3 str. Alaska E43, complete genomesheath tail protein5e-22105
NC_017297:2531750:2542632254263225439421311Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein7e-1479
NC_009089:1093832:10873831087383114439857016Clostridium difficile 630, complete genome9e-1788.6
NC_009706:3291330:3330322333032233317491428Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein5e-154544
NC_009706:2023912:2025050202505020264681419Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein6e-145514
NC_011837:3226500:3261824326182432632511428Clostridium kluyveri NBRC 12016, complete genomehypothetical protein5e-154544
NC_010001:986500:1010397101039710116771281Clostridium phytofermentans ISDg, complete genomephage protein5e-1066.2
NC_010001:3614314:3626064362606436273711308Clostridium phytofermentans ISDg, complete genomephage protein2e-0653.9
NC_014376:1472304:1500202150020215012421041Clostridium saccharolyticum WM1 chromosome, complete genomehypothetical protein2e-0757.4
NC_020291:795500:8465788465788478851308Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomephage-like element PBSX protein XkdK3e-1790.1
NC_020291:795500:8327858327858339061122Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomephage tail sheath protein4e-0653.1
NC_020134:420500:4407794407794418191041Clostridium stercorarium subsp. stercorarium DSM 8532, completephage tail sheath protein6e-1375.9
NC_009012:2953638:2955379295537929564251047Clostridium thermocellum ATCC 27405, complete genomehypothetical protein6e-1169.3
NC_011830:1504497:1517316151731615186321317Desulfitobacterium hafniense DCB-2, complete genomephage protein2e-23110
NC_018515:3411276:3431632343163234329481317Desulfosporosinus meridiei DSM 13257 chromosome, complete genomePhage tail sheath protein4e-27122
NC_013216:4404085:4409190440919044106381449Desulfotomaculum acetoxidans DSM 771, complete genomehypothetical protein2e-92340
NC_012673:1:2781027810292011392Exiguobacterium sp. AT1b, complete genomehypothetical protein3e-21103
NC_015520:595532:6121426121426135931452Mahella australiensis 50-1 BON chromosome, complete genomehypothetical protein4e-94345
NC_014483:1179286:1184497118449711859631467Paenibacillus polymyxa E681 chromosome, complete genomehypothetical protein1e-77290
NC_014622:3676859:3688004368800436893561353Paenibacillus polymyxa SC2 chromosome, complete genomehypothetical protein8e-25115
NC_012914:5938566:5938566593856659398821317Paenibacillus sp. JDR-2, complete genomehypothetical protein1e-1791.7
NC_013406:6052913:6059465605946560607841320Paenibacillus sp. Y412MC10 chromosome, complete genomephage protein2e-1687.4
NC_016641:2950000:2953366295336629548321467Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein4e-78292
NC_013517:1501276:1508528150852815098351308Sebaldella termitidis ATCC 33386, complete genomehypothetical protein2e-0757.8