Pre_GI: BLASTP Hits

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Query: NC_012563:2566500:2572186 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2572186, End: 2573154, Length: 969

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009633:2592000:259903425990342599987954Alkaliphilus metalliredigens QYMF chromosome, complete genomehypothetical protein7e-76284
UCMB5137:861734:876184876184877161978Bacillus atrophaeus UCMB-5137hypothetical protein2e-1067
NC_009848:2755874:2760320276032027613301011Bacillus pumilus SAFR-032, complete genomehypothetical protein5e-0962
NC_014976:627935:655877655877656857981Bacillus subtilis BSn5 chromosome, complete genomehypothetical protein7e-1271.6
NC_014976:3546884:355351035535103554487978Bacillus subtilis BSn5 chromosome, complete genomehypothetical protein3e-0963.2
NC_014479:1291500:129780712978071298784978Bacillus subtilis subsp. spizizenii str. W23 chromosome, completehypothetical protein1e-0963.9
NC_016047:261304:267311267311268291981Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completehypothetical protein1e-1170.5
NC_016047:1435961:144588614458861446863978Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completehypothetical protein1e-0963.9
NC_000964:2670288:267028826702882671268981Bacillus subtilis subsp. subtilis str. 168, complete genomehypothetical protein7e-1271.6
NC_000964:1330000:133894513389451339922978Bacillus subtilis subsp. subtilis str. 168, complete genomehypothetical protein3e-0963.2
NC_019896:2719456:272936627293662730343978Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completePhage-like element PBSX protein XkdQ3e-0963.2
NC_017195:1308730:131650013165001317480981Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completehypothetical protein3e-0962.8
NC_020244:1335531:134276213427621343742981Bacillus subtilis XF-1, complete genomehypothetical protein5e-0962.4
NC_014652:801653:826540826540827538999Caldicellulosiruptor hydrothermalis 108 chromosome, completehypothetical protein1e-1687
NC_009495:2479465:248416624841662485134969Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein2e-167588
NC_010674:2817651:2829664282966428306831020Clostridium botulinum B str. Eklund 17B, complete genomehypothetical protein2e-84312
NC_009706:3291330:332027533202753321261987Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein3e-99362
NC_009706:1935418:194115519411551942141987Clostridium kluyveri DSM 555 chromosome, complete genomeXkdQ-like protein7e-99360
NC_009706:2003194:200951920095192010505987Clostridium kluyveri DSM 555 chromosome, complete genomeXkdQ-like protein7e-99360
NC_011837:1935294:194103119410311942017987Clostridium kluyveri NBRC 12016, complete genomehypothetical protein7e-99360
NC_011837:3226500:325177732517773252763987Clostridium kluyveri NBRC 12016, complete genomehypothetical protein3e-99362
NC_013216:4404085:441678744167874417785999Desulfotomaculum acetoxidans DSM 771, complete genomehypothetical protein5e-67254
NC_012673:1:3354033540353871848Exiguobacterium sp. AT1b, complete genomeNLP/P60 protein1e-0551.2
NC_014483:1179286:118988611898861190863978Paenibacillus polymyxa E681 chromosome, complete genomehypothetical protein2e-60232
NC_013406:6052913:606697760669776067954978Paenibacillus sp. Y412MC10 chromosome, complete genomehypothetical protein1e-57223
NC_016641:2950000:295869429586942959671978Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein3e-61235