Pre_GI: BLASTP Hits

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Query: NC_012563:122000:141684 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 141684, End: 142697, Length: 1014

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:122000:1425571425571435701014Clostridium botulinum F str. Langeland chromosome, complete genomespore coat protein4e-172603
NC_009698:120119:1405531405531415661014Clostridium botulinum A str. Hall chromosome, complete genomespore coat protein4e-171600
NC_009697:120117:1405511405511415641014Clostridium botulinum A str. ATCC 19397 chromosome, completespore coat protein4e-171600
NC_009495:128000:1477481477481487611014Clostridium botulinum A str. ATCC 3502 chromosome, complete genomespore coat protein4e-171600
NC_012658:125500:1451901451901462031014Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative spore coat protein2e-168591
NC_010520:121077:1415321415321425451014Clostridium botulinum A3 str. Loch Maree, complete genomeputative spore coat protein8e-168589
NC_010516:127000:1475411475411485541014Clostridium botulinum B1 str. Okra, complete genomeputative spore coat protein4e-165580
NC_017297:122383:142821142821143807987Clostridium botulinum F str. 230613 chromosome, complete genomeCotS family spore coat protein1e-160566
NC_008593:2250871:226371322637132264684972Clostridium novyi NT, complete genomespore coat protein S, putative2e-84313
NC_008261:2743942:2756479275647927575071029Clostridium perfringens ATCC 13124, complete genomeputative spore coat protein7e-56218
NC_008593:2250871:2250871225087122518811011Clostridium novyi NT, complete genomespore coat protein6e-39161
NC_015949:1887478:188833318883331889325993Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomespore coat protein, CotS family4e-38159
NC_008261:2743942:2754056275405627550601005Clostridium perfringens ATCC 13124, complete genomespore coat protein CotS6e-37154
NC_009698:120119:1431651431651441691005Clostridium botulinum A str. Hall chromosome, complete genomespore coat protein CotS2e-35149
NC_009697:120117:1431631431631441671005Clostridium botulinum A str. ATCC 19397 chromosome, completespore coat protein CotS2e-35149
NC_010516:127000:1501521501521511561005Clostridium botulinum B1 str. Okra, complete genomespore coat protein CotS2e-35149
NC_010516:127000:1455151455151465251011Clostridium botulinum B1 str. Okra, complete genomeputative spore coat protein1e-32140
NC_009699:122000:1405311405311415411011Clostridium botulinum F str. Langeland chromosome, complete genomespore coat protein4e-32139
NC_017297:122383:1407951407951418051011Clostridium botulinum F str. 230613 chromosome, complete genomeCotS family spore coat protein4e-32139
NC_010520:121077:1395061395061405161011Clostridium botulinum A3 str. Loch Maree, complete genomeputative spore coat protein2e-32139
NC_008261:2743942:2758214275821427592211008Clostridium perfringens ATCC 13124, complete genomeputative spore coat protein7e-32138
NC_012658:125500:1431641431641441741011Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative spore coat protein7e-32138
NC_009698:120119:1385271385271395371011Clostridium botulinum A str. Hall chromosome, complete genomespore coat protein2e-31136
NC_009697:120117:1385251385251395351011Clostridium botulinum A str. ATCC 19397 chromosome, completespore coat protein2e-31136
NC_009495:128000:1457221457221467321011Clostridium botulinum A str. ATCC 3502 chromosome, complete genomespore coat protein2e-31136
NC_012563:122000:1396581396581406681011Clostridium botulinum A2 str. Kyoto, complete genomespore coat protein, CotS family2e-31136
NC_015949:1887478:1890331189033118913321002Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomespore coat protein, CotS family2e-26120
NC_008593:2250871:2265569226556922665821014Clostridium novyi NT, complete genomespore coat protein S, putative2e-26120
NC_021182:2667408:2684796268479626858421047Clostridium pasteurianum BC1, complete genomespore coat protein, CotS family8e-21101
NC_021182:2219286:2224360222436022254121053Clostridium pasteurianum BC1, complete genomespore coat protein, CotS family3e-1479.7
NC_020291:1045058:1066248106624810673121065Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomespore coat protein CotS4e-1375.9
NC_003366:2286083:2302395230239523034741080Clostridium perfringens str. 13, complete genomeprobable spore coat protein5e-1272.4
NC_008262:2169262:2185546218554621866251080Clostridium perfringens SM101, complete genomehypothetical protein7e-1271.6
NC_014650:1942935:1951363195136319524571095Geobacillus sp. Y4.1MC1 chromosome, complete genomespore coat protein, CotS family2e-0963.9
NC_015660:1988000:1989515198951519906091095Geobacillus thermoglucosidasius C56-YS93 chromosome, completespore coat protein, CotS family4e-0962.4
NC_014393:1782811:1794836179483617959061071Clostridium cellulovorans 743B chromosome, complete genomespore coat protein, CotS family4e-0755.8