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Query: NC_012563:122000:133635 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 133635, End: 134441, Length: 807

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010516:127000:139492139492140298807Clostridium botulinum B1 str. Okra, complete genomeconserved hypothetical protein TIGR002682e-150531
NC_009698:120119:132504132504133310807Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein5e-150530
NC_009697:120117:132502132502133308807Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein5e-150530
NC_009495:128000:139699139699140505807Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein5e-150530
NC_017297:122383:134773134773135579807Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein3e-149527
NC_009699:122000:134508134508135314807Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein3e-149527
NC_010520:121077:133486133486134292807Clostridium botulinum A3 str. Loch Maree, complete genomeconserved hypothetical protein TIGR002689e-146515
NC_012658:125500:137144137144137950807Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein1e-141502
NC_019978:315346:321048321048321878831Halobacteroides halobius DSM 5150, complete genomeTIGR00268 family protein1e-67256
NC_016627:3158353:317466131746613175467807Clostridium clariflavum DSM 19732 chromosome, complete genomehypothetical protein1e-65249
NC_007503:1111457:114127611412761142103828Carboxydothermus hydrogenoformans Z-2901, complete genomeconserved hypothetical protein TIGR002682e-64245
NC_014206:1618988:163005116300511630875825Geobacillus sp. C56-T3 chromosome, complete genomeasparagine synthase1e-62239
NC_006510:1995916:200799820079982008822825Geobacillus kaustophilus HTA426, complete genomehypothetical protein1e-62239
NC_015565:2027279:205581420558142056635822Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completehypothetical protein4e-57221
NC_016023:1874827:188688418868841887693810Bacillus coagulans 36D1 chromosome, complete genomehypothetical protein3e-55215
NC_021184:592501:594161594161594973813Desulfotomaculum gibsoniae DSM 7213, complete genomeTIGR00268 family protein4e-55214
NC_014378:261064:280949280949281767819Acetohalobium arabaticum DSM 5501 chromosome, complete genomePP-loop domain protein9e-55213
NC_012108:2037429:205316720531672053997831Desulfobacterium autotrophicum HRM2, complete genomeATP-utilizing protein of the PP-loop superfamily4e-54211
NC_009486:1737703:179026617902661791072807Thermotoga petrophila RKU-1 chromosome, complete genomeExsB family protein2e-52206
NC_013741:27353:408874088741666780Archaeoglobus profundus DSM 5631, complete genomeExsB family protein5e-52204
NC_008816:1476209:151058015105801511404825Prochlorococcus marinus str. AS9601, complete genomeATP-utilizing enzymes of the PP-loop superfamily9e-48190
NC_008817:1538507:154405215440521544810759Prochlorococcus marinus str. MIT 9515, complete genomeATP-utilizing enzymes of the PP-loop superfamily1e-47189
NC_007955:1498777:151106115110611511864804Methanococcoides burtonii DSM 6242, complete genomehypothetical protein8e-46184
NC_011832:1148859:118098411809841181799816Candidatus Methanosphaerula palustris E1-9c, complete genomePP-loop domain-containing protein3e-45181
NC_015320:1159613:116026811602681161041774Archaeoglobus veneficus SNP6 chromosome, complete genomehypothetical protein1e-38160
NC_013173:8923:312643126432085822Desulfomicrobium baculatum DSM 4028, complete genomehypothetical protein2e-24112
NC_015636:288797:287988287988288803816Methanothermococcus okinawensis IH1 chromosome, complete genomehypothetical protein5e-1994.7
NC_015954:463500:4768114768114780341224Halophilic archaeon DL31 chromosome, complete genomeArgininosuccinate synthase6e-0651.6