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Query: NC_012207:831030:852485 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 852485, End: 852670, Length: 186

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017026:829444:850851850851851036186Mycobacterium tuberculosis RGTB327 chromosome, complete genomehypothetical protein2e-27121
NC_016768:830000:851544851544851729186Mycobacterium tuberculosis KZN 4207 chromosome, complete genometransposase2e-27121
NC_012943:830000:851540851540851725186Mycobacterium tuberculosis KZN 1435 chromosome, complete genometransposase2e-27121
NC_002945:831029:852532852532852717186Mycobacterium bovis AF2122/97, complete genometransposase2e-27121
NC_002944:865425:8727728727728739591188Mycobacterium avium subsp. paratuberculosis K-10, complete genomehypothetical protein3e-2097.1
NC_008726:610000:6138536138536156461794Mycobacterium vanbaalenii PYR-1, complete genomeIntegrase, catalytic region1e-0755.1
NC_003155:4592000:4623466462346646252351770Streptomyces avermitilis MA-4680, complete genomeISmav2-like transposase2e-0754.3
NC_013235:1761539:1766259176625917680821824Nakamurella multipartita DSM 44233, complete genomeIntegrase catalytic region1e-0548.9