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Query: NC_012207:831030:831030 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 831030, End: 831527, Length: 498

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017026:829444:829704829704830201498Mycobacterium tuberculosis RGTB327 chromosome, complete genomeMarR family transcriptional regulator6e-79292
NC_008769:860670:860670860670861167498Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomeputative transcriptional regulatory protein6e-79292
NC_002945:831029:831029831029831526498Mycobacterium bovis AF2122/97, complete genometranscriptional regulatory protein6e-79292
NC_009565:833076:833076833076833573498Mycobacterium tuberculosis F11, complete genomehypothetical transcriptional regulatory protein6e-79292
NC_002755:831397:831397831397831894498Mycobacterium tuberculosis CDC1551, complete genometranscriptional regulator, MarR family6e-79292
NC_009525:830513:830513830513831010498Mycobacterium tuberculosis H37Ra, complete genomeputative transcriptional regulatory protein6e-79292
NC_012943:830000:830207830207830704498Mycobacterium tuberculosis KZN 1435 chromosome, complete genometranscriptional regulator6e-79292
NC_016768:830000:830211830211830708498Mycobacterium tuberculosis KZN 4207 chromosome, complete genometranscriptional regulator6e-79292
NC_019673:8057941:806683980668398067342504Saccharothrix espanaensis DSM 44229 complete genomeTranscriptional regulator, MarR family6e-24109
NC_013595:4796436:482363748236374824152516Streptosporangium roseum DSM 43021, complete genomehypothetical protein2e-0652