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Query: NC_012207:3421144:3434837 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 3434837, End: 3435151, Length: 315

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002945:3429315:3444248344424834454231176Mycobacterium bovis AF2122/97, complete genomePPE family protein2e-31134
NC_016804:3407859:342155234215523421866315Mycobacterium bovis BCG str. Mexico chromosome, complete genomePPE family protein2e-30130
NC_008769:3427254:344218734421873442501315Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomePPE family protein2e-30130
NC_002755:3465582:3486273348627334874481176Mycobacterium tuberculosis CDC1551, complete genomePPE family protein2e-31134
NC_009565:3485772:3503599350359935047741176Mycobacterium tuberculosis F11, complete genomePPE family protein2e-31134
NC_009525:3484924:3502632350263235038071176Mycobacterium tuberculosis H37Ra, complete genomePPE family protein2e-31134
NC_000962:3474000:3490476349047634916511176Mycobacterium tuberculosis H37Rv, complete genomePPE FAMILY PROTEIN2e-31134
NC_017026:3466809:3484534348453434857091176Mycobacterium tuberculosis RGTB327 chromosome, complete genomePPE family protein2e-31134