Pre_GI: BLASTP Hits

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Query: NC_012207:3421144:3433867 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 3433867, End: 3434736, Length: 870

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016804:3407859:342058234205823421451870Mycobacterium bovis BCG str. Mexico chromosome, complete genomeputative transcriptional regulatory protein2e-167587
NC_008769:3427254:344121734412173442086870Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomeputative transcriptional regulatory protein2e-167587
NC_009565:3485772:350260535026053503498894Mycobacterium tuberculosis F11, complete genomehypothetical transcriptional regulatory protein1e-166585
NC_002755:3465582:348523734852373486172936Mycobacterium tuberculosis CDC1551, complete genometranscriptional regulator, AfsR/DnrI/RedD family1e-166585
NC_009525:3484924:350166235016623502531870Mycobacterium tuberculosis H37Ra, complete genomeputative transcriptional regulatory protein2e-166585
NC_000962:3474000:348950634895063490375870Mycobacterium tuberculosis H37Rv, complete genomePROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN2e-166585
NC_002945:3429315:344327834432783444147870Mycobacterium bovis AF2122/97, complete genometranscriptional regulatory protein2e-166585
NC_017026:3466809:348378634837863484433648Mycobacterium tuberculosis RGTB327 chromosome, complete genometranscriptional regulator1e-120432
NC_009953:3509229:3521491352149135234551965Salinispora arenicola CNS-205 chromosome, complete genomeSARP family transcriptional regulator1e-35150
NC_013757:900500:9101879101879131893003Geodermatophilus obscurus DSM 43160, complete genometranscriptional regulator, SARP family2e-29129
NC_013757:2659930:2674458267445826773312874Geodermatophilus obscurus DSM 43160, complete genometranscriptional regulator, winged helix family4e-29128
NC_008278:2732890:2752317275231727554123096Frankia alni ACN14a, complete genomeputative regulatory protein (AfsR-like protein)4e-29128
NC_014666:4419693:4419693441969344229983306Frankia sp. EuI1c chromosome, complete genometranscriptional regulator, SARP family7e-29127
NC_009921:5787437:5806001580600158089402940Frankia sp. EAN1pec, complete genometranscriptional regulator, SARP family7e-27121
NC_013595:3712257:3727790372779037307052916Streptosporangium roseum DSM 43021, complete genometranscriptional regulator, SARP family2e-25115
NC_013595:4796436:4796436479643647994262991Streptosporangium roseum DSM 43021, complete genometranscriptional regulator, SARP family8e-25114
NC_013595:4758034:4774316477431647776603345Streptosporangium roseum DSM 43021, complete genomeATPase-like protein2e-24113
NC_016582:6999074:7026400702640070305004101Streptomyces bingchenggensis BCW-1 chromosome, complete genomeAfsR-like regulatory protein6e-24111
NC_013595:4031947:4052565405256540556573093Streptosporangium roseum DSM 43021, complete genometranscriptional regulator, SARP family8e-24110
NC_013093:7222000:7228008722800872311183111Actinosynnema mirum DSM 43827, complete genometranscriptional regulator, SARP family1e-23110
NC_015957:7408466:744725174472517448081831Streptomyces violaceusniger Tu 4113 chromosome, complete genomeSARP family transcriptional regulator4e-23108
NC_009953:4748147:4759217475921747610821866Salinispora arenicola CNS-205 chromosome, complete genomeSARP family transcriptional regulator6e-23108
NC_013947:1956923:1965214196521419679792766Stackebrandtia nassauensis DSM 44728 chromosome, complete genometranscriptional regulator, SARP family6e-23108
NC_013235:5849659:5871616587161658748973282Nakamurella multipartita DSM 44233, complete genometranscriptional regulator, winged helix family4e-22105
NC_018524:4848154:4849992484999248519711980Nocardiopsis alba ATCC BAA-2165 chromosome, complete genometranscriptional regulator, SARP family protein6e-22104
NC_016109:4199839:4211154421115442143213168Kitasatospora setae KM-6054, complete genomeputative AfsR family transcriptional regulator2e-21103
NC_014666:300571:324495324495325316822Frankia sp. EuI1c chromosome, complete genometranscriptional regulator, SARP family5e-21101
NC_020302:2116468:2137332213733221388551524Corynebacterium halotolerans YIM 70093 = DSM 44683, completeATPase-like protein1e-20100
NC_013093:626473:6338026338026366422841Actinosynnema mirum DSM 43827, complete genometranscriptional regulator, SARP family2e-2099.8
NC_016943:1314500:1314500131450013177873288Blastococcus saxobsidens DD2, complete genomeMulti-domain regulatory protein3e-2099.4
NC_018750:5078705:5093644509364450963372694Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein3e-2099.4
NC_013947:1570000:1577359157735915804423084Stackebrandtia nassauensis DSM 44728 chromosome, complete genometranscriptional regulator, SARP family6e-2098.2
NC_016109:6507076:6527002652700265300583057Kitasatospora setae KM-6054, complete genomeputative AfsR family transcriptional regulator6e-2098.2
NC_013595:3712257:3713298371329837163603063Streptosporangium roseum DSM 43021, complete genometranscriptional regulator, SARP family7e-2097.8
NC_014815:2055286:2070183207018320734463264Micromonospora sp. L5 chromosome, complete genometranscriptional regulator, winged helix family1e-1997.1
NC_013757:1732747:1743495174349517463262832Geodermatophilus obscurus DSM 43160, complete genometranscriptional regulator, winged helix family2e-1996.7
NC_009142:6086000:6090748609074860943023555Saccharopolyspora erythraea NRRL 2338, complete genomehypothetical protein4e-1995.5
NC_003155:2211087:2212064221206422143222259Streptomyces avermitilis MA-4680, complete genomeregulatory protein2e-1893.6
NC_015312:61752:7863778637814442808Pseudonocardia dioxanivorans CB1190 chromosome, complete genomewinged helix family transcriptional regulator2e-1893.2
NC_013947:460398:4835324835324866183087Stackebrandtia nassauensis DSM 44728 chromosome, complete genometranscriptional regulator, winged helix family3e-1892.4
NC_019673:6473743:6483586648358664864052820Saccharothrix espanaensis DSM 44229 complete genomeTranscriptional regulator, SARP family4e-1892.4
NC_014318:8590078:8595280859528085983393060Amycolatopsis mediterranei U32 chromosome, complete genomeSARP family transcriptional regulator4e-1892
NC_017186:8588000:8595336859533685983953060Amycolatopsis mediterranei S699 chromosome, complete genomeSARP family transcriptional regulator4e-1892
NC_013947:4413382:4426906442690644298572952Stackebrandtia nassauensis DSM 44728 chromosome, complete genometranscriptional regulator, SARP family5e-1891.7
NC_015656:2900730:291570029157002916479780Frankia symbiont of Datisca glomerata chromosome, complete genomeSARP family transcriptional regulator7e-1891.3
NC_008146:1535827:1535827153582715392523426Mycobacterium sp. MCS, complete genometranscriptional regulator, SARP family2e-1789.4
NC_008705:1537080:1540135154013515435603426Mycobacterium sp. KMS, complete genometranscriptional regulator, SARP family2e-1789.4
NC_019673:1275627:1306946130694613101193174Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein3e-1789.4
NC_019673:3253650:3276007327600732792493243Saccharothrix espanaensis DSM 44229 complete genomeATPase-like protein8e-1787.8
NC_019673:4687289:4697284469728447004093126Saccharothrix espanaensis DSM 44229 complete genomeProtein kinase1e-1687.4
NC_009953:5733211:574151357415135742403891Salinispora arenicola CNS-205 chromosome, complete genomeSARP family transcriptional regulator1e-1687
NC_015957:8816355:882305788230578823833777Streptomyces violaceusniger Tu 4113 chromosome, complete genome3e-1685.9
NC_015953:5865733:586876158687615869573813Streptomyces sp. SirexAA-E chromosome, complete genomeSARP family transcriptional regulator1e-1584
NC_017186:6539181:6543439654343965462282790Amycolatopsis mediterranei S699 chromosome, complete genomeSARP family transcriptional regulator1e-1584
NC_014318:6539137:6543395654339565461842790Amycolatopsis mediterranei U32 chromosome, complete genomeSARP family transcriptional regulator1e-1584
NC_013947:6678000:6692591669259166956953105Stackebrandtia nassauensis DSM 44728 chromosome, complete genometranscriptional regulator, SARP family5e-1582
NC_016109:7445603:7465978746597874689773000Kitasatospora setae KM-6054, complete genomeputative AfsR family transcriptional regulator2e-1376.6
NC_016111:3577572:3599142359914236023393198Streptomyces cattleya NRRL 8057, complete genomeAfsR-like regulatory protein2e-1376.3
NC_013729:380312:3858953858953878261932Kribbella flavida DSM 17836, complete genometranscriptional regulator, SARP family4e-1272
NC_013093:4522751:452275145227514523536786Actinosynnema mirum DSM 43827, complete genometranscriptional regulator, SARP family2e-1067
NC_013159:3858425:3858425385842538616073183Saccharomonospora viridis DSM 43017, complete genomepredicted ATPase1e-0963.9
NC_013947:5682895:5695664569566456984052742Stackebrandtia nassauensis DSM 44728 chromosome, complete genometranscriptional regulator, SARP family6e-0961.6
NC_013739:5535945:556073855607385561439702Conexibacter woesei DSM 14684, complete genome1e-0757.4
NC_015723:430165:4335914335914375383948Cupriavidus necator N-1 chromosome 2, complete sequenceadenylate/guanylate cyclase4e-0755.5
NC_014219:999648:1007214100721410083561143Bacillus selenitireducens MLS10 chromosome, complete genomeresponse regulator receiver and SARP domain protein2e-0653.5
NC_009483:2201986:224126822412682241900633Geobacter uraniireducens Rf4 chromosome, complete genomeSARP family transcriptional regulator2e-0652.8