Pre_GI: BLASTP Hits

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Query: NC_012207:3421144:3426837 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 3426837, End: 3427088, Length: 252

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017026:3466809:347374434737443473995252Mycobacterium tuberculosis RGTB327 chromosome, complete genomemolybdenum cofactor biosynthesis protein D1e-42171
NC_002755:3465582:347549734754973475748252Mycobacterium tuberculosis CDC1551, complete genomemolybdenum cofactor biosynthesis protein D1e-42171
NC_002945:3429315:343624834362483436499252Mycobacterium bovis AF2122/97, complete genomemolybdenum cofactor biosynthesis protein D1e-42171
NC_000962:3474000:347970034797003479951252Mycobacterium tuberculosis H37Rv, complete genomePROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN D MOAD1 (MOLYBDOPTERIN CONVERTING FACTOR SMALL SUBUNIT) (MOLYBDOPTERIN [MPT] CONVERTING FACTOR, SUBU1e-42171
NC_009525:3484924:349185634918563492107252Mycobacterium tuberculosis H37Ra, complete genomemolybdenum cofactor biosynthesis protein D11e-42171
NC_008769:3427254:343418734341873434438252Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomeputative molybdenum cofactor biosynthesis protein D moaD11e-42171
NC_009565:3485772:349146534914653491716252Mycobacterium tuberculosis F11, complete genomemolybdenum cofactor biosynthesis protein D moaD11e-42171
NC_016804:3407859:341355234135523413803252Mycobacterium bovis BCG str. Mexico chromosome, complete genomemolybdenum cofactor biosynthesis protein D1e-42171
NC_012438:50845:707207072070962243Sulfurihydrogenibium azorense Az-Fu1 chromosome, complete genomehypothetical protein6e-0959.7
NC_009376:2102536:211667921166792117365687Pyrobaculum arsenaticum DSM 13514 chromosome, complete genomeMoaD family protein9e-0855.5
NC_016885:2091918:216835121683512169037687Pyrobaculum oguniense TE7 chromosome, complete genomeMoaD family protein, archaeal9e-0855.5
NC_003364:402268:403769403769404458690Pyrobaculum aerophilum str. IM2, complete genomemolybdenum cofactor biosynthesis protein D/E6e-0753.1