Pre_GI: BLASTP Hits

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Query: NC_012207:3421144:3425916 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 3425916, End: 3426311, Length: 396

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002755:3465582:347454334745433474971429Mycobacterium tuberculosis CDC1551, complete genomepterin-4-alpha-carbinolamine dehydratase1e-73274
NC_017026:3466809:347282334728233473218396Mycobacterium tuberculosis RGTB327 chromosome, complete genomepterin-4-alpha-carbinolamine dehydratase2e-73273
NC_016804:3407859:341263134126313413026396Mycobacterium bovis BCG str. Mexico chromosome, complete genomePterin-4-alpha-carbinolamine dehydratase2e-73273
NC_000962:3474000:347877934787793479174396Mycobacterium tuberculosis H37Rv, complete genomePROBABLE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE MOAB1 (PHS) (4-ALPHA-HYDROXY-TETRAHYDROPTERIN DEHYDRATASE) (PTERIN-4-A-CARBINOLAMINE DEHYDRATASE) (P2e-73273
NC_009525:3484924:349093534909353491330396Mycobacterium tuberculosis H37Ra, complete genomepterin-4-alpha-carbinolamine dehydratase MoaB12e-73273
NC_009565:3485772:349054434905443490939396Mycobacterium tuberculosis F11, complete genomepterin-4-alpha-carbinolamine dehydratase moaB12e-73273
NC_008769:3427254:343326634332663433661396Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomeputative pterin-4-alpha-carbinolamine dehydratase moaB12e-73273
NC_002945:3429315:343532734353273435722396Mycobacterium bovis AF2122/97, complete genomepterin-4-alpha-carbinolamine dehydratase MoaB12e-73273
NC_009481:1638394:165646916564691656750282Synechococcus sp. WH 7803 chromosome, complete genomeputative pterin-4-alpha-carbinolamine dehydratase1e-0858.5
NC_008148:2053467:207059520705952070918324Rubrobacter xylanophilus DSM 9941, complete genometranscriptional coactivator/pterin dehydratase1e-0858.5
NC_020210:2044944:206551320655132065803291Geobacillus sp. GHH01, complete genometranscriptional activator1e-0858.5
NC_016002:2453919:245578324557832456112330Pseudogulbenkiania sp. NH8B, complete genomepterin-4-alpha-carbinolamine dehydratase8e-0855.8
NC_017271:2449504:246981924698192470175357Xanthomonas campestris pv. raphani 756C chromosome, completeputative pterin-4-alpha-carbinolamine dehydratase2e-0754.3
NC_007940:1485006:150411515041151504456342Rickettsia bellii RML369-C, complete genomePutative pterin-4-alpha-carbinolamine dehydratase3e-0650.8
NC_009883:1492425:151102315110231511364342Rickettsia bellii OSU 85-389, complete genomePutative pterin-4-alpha-carbinolamine dehydratase3e-0650.8
NC_013510:1023348:102637910263791026687309Thermomonospora curvata DSM 43183, complete genometranscriptional coactivator/pterin dehydratase4e-0650.1