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Query: NC_012207:3421144:3424197 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 3424197, End: 3424637, Length: 441

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002755:3465582:347278834727883473297510Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein2e-80296
NC_016804:3407859:341091234109123411352441Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein6e-80295
NC_008769:3427254:343154734315473431987441Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein6e-80295
NC_009565:3485772:348882534888253489265441Mycobacterium tuberculosis F11, complete genomehypothetical protein6e-80295
NC_009525:3484924:348921634892163489656441Mycobacterium tuberculosis H37Ra, complete genomehypothetical protein6e-80295
NC_000962:3474000:347706034770603477500441Mycobacterium tuberculosis H37Rv, complete genomehypothetical protein6e-80295
NC_002945:3429315:343360834336083434048441Mycobacterium bovis AF2122/97, complete genomehypothetical protein8e-80295
NC_002755:3465582:348749934874993487663165Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein8e-0649.3