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Query: NC_012207:1097228:1116011 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 1116011, End: 1116262, Length: 252

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017026:1095753:111455011145501114801252Mycobacterium tuberculosis RGTB327 chromosome, complete genomehypothetical protein3e-43173
NC_016804:1095846:111462911146291114880252Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein3e-43173
NC_002755:1095105:111389911138991114150252Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein3e-43173
NC_008769:1125567:114435011443501144601252Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein3e-43173
NC_009525:1096386:111516911151691115420252Mycobacterium tuberculosis H37Ra, complete genomehypothetical protein3e-43173
NC_009565:1098847:111762911176291117880252Mycobacterium tuberculosis F11, complete genomehypothetical protein3e-43173