Pre_GI: BLASTP Hits

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Query: NC_012207:1097228:1115784 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 1115784, End: 1116014, Length: 231

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016804:1095846:111440211144021114632231Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein8e-37152
NC_008769:1125567:114412311441231144353231Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein8e-37152
NC_002755:1095105:111367311136731113813141Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein2e-1168.2