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Query: NC_011896:563641 Mycobacterium leprae Br4923, complete genome

Start: 563641, End: 583453, Length: 19813

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_002677:56350056350058344419945Mycobacterium leprae TN, complete genome029330BLASTN svgBLASTP svg
NC_011896:34746*347465709922354Mycobacterium leprae Br4923, complete genome01261BLASTN svgBLASTP svg
NC_002677:34750*347505709922350Mycobacterium leprae TN, complete genome01261BLASTN svgBLASTP svg
NC_011896:10965001096500111521218713Mycobacterium leprae Br4923, complete genome01241BLASTN svgBLASTP svg
NC_002677:26428602642860268248339624Mycobacterium leprae TN, complete genome01241BLASTN svgBLASTP svg
NC_002677:10965001096500111516918670Mycobacterium leprae TN, complete genome01233BLASTN svgBLASTP svg
NC_011896:26609692660969268009919131Mycobacterium leprae Br4923, complete genome01138BLASTN svgBLASTP svg
NC_014039:12385001238500126344824949Propionibacterium acnes SK137 chromosome, complete genome2e-22115BLASTN svgBLASTP svg
NC_006085:12345871234587126026325677Propionibacterium acnes KPA171202, complete genome4e-20107BLASTN svgBLASTP svg
NC_019673:32536503253650327924925600Saccharothrix espanaensis DSM 44229 complete genome1e-1489.7BLASTN svgBLASTP svg