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Query: NC_011896:363448 Mycobacterium leprae Br4923, complete genome

Start: 363448, End: 388949, Length: 25502

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_002677:36343236343238893225501Mycobacterium leprae TN, complete genome050510BLASTN svgBLASTP svg
NC_010612:83564883564886299927352Mycobacterium marinum M, complete genome0741BLASTN svgBLASTP svg
NC_015848:48350048350050998826489Mycobacterium canettii CIPT 140010059, complete genome01140BLASTN svgBLASTP svg
NC_002945:47683547683550063823804Mycobacterium bovis AF2122/97, complete genome01174BLASTN svgBLASTP svg
NC_008769:50700050700053043423435Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome01174BLASTN svgBLASTP svg
NC_012207:47750047750050076723268Mycobacterium bovis BCG str. Tokyo 172, complete genome01174BLASTN svgBLASTP svg
NC_000962:47581647581649961923804Mycobacterium tuberculosis H37Rv, complete genome01179BLASTN svgBLASTP svg
NC_009525:47709347709350092923837Mycobacterium tuberculosis H37Ra, complete genome01179BLASTN svgBLASTP svg
NC_009565:47950047950050278923290Mycobacterium tuberculosis F11, complete genome01179BLASTN svgBLASTP svg
NC_019950:48188148188150600724127Mycobacterium canettii CIPT 140060008 complete genome01187BLASTN svgBLASTP svg
NC_002677:10965001096500111516918670Mycobacterium leprae TN, complete genome04758BLASTN svgBLASTP svg
NC_011896:10965001096500111521218713Mycobacterium leprae Br4923, complete genome04758BLASTN svgBLASTP svg
NC_003295:11277811277813226319486Ralstonia solanacearum GMI1000, complete genome2e-29139BLASTN svgBLASTP svg
NC_004578:56237835623783565173727955Pseudomonas syringae pv. tomato str. DC3000, complete genome4e-27131BLASTN svgBLASTP svg
NC_013169:20450002045000206559920600Kytococcus sedentarius DSM 20547, complete genome2e-25125BLASTN svgBLASTP svg
NC_008278:874015*87401590122927215Frankia alni ACN14a, complete genome1e-23119BLASTN svgBLASTP svg
NC_012590:2501593*2501593252409922507Corynebacterium aurimucosum ATCC 700975, complete genome2e-19105BLASTN svgBLASTP svg
NC_003888:43143894314389433545821070Streptomyces coelicolor A3(2), complete genome3e-1591.7BLASTN svgBLASTP svg
NC_011901:491783*49178352043828656Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, complete2e-1075.8BLASTN svgBLASTP svg
NC_013131:97115089711508973462123114Catenulispora acidiphila DSM 44928, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_015593:2103815*2103815214825244438Sphingobium chlorophenolicum L-1 chromosome chromosome 1, complete3e-0661.9BLASTN svgBLASTP svg