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Query: NC_011896:34746 Mycobacterium leprae Br4923, complete genome

Start: 34746, End: 57099, Length: 22354

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_002677:34750*347505709922350Mycobacterium leprae TN, complete genome033840BLASTN svgBLASTP svg
NC_011896:30405003040500306213921640Mycobacterium leprae Br4923, complete genome02635BLASTN svgBLASTP svg
NC_002677:30407113040711306032819618Mycobacterium leprae TN, complete genome02635BLASTN svgBLASTP svg
NC_011896:56364156364158345319813Mycobacterium leprae Br4923, complete genome01265BLASTN svgBLASTP svg
NC_002677:56350056350058344419945Mycobacterium leprae TN, complete genome01265BLASTN svgBLASTP svg
NC_011896:10965001096500111521218713Mycobacterium leprae Br4923, complete genome01241BLASTN svgBLASTP svg
NC_002677:26428602642860268248339624Mycobacterium leprae TN, complete genome01237BLASTN svgBLASTP svg
NC_002677:10965001096500111516918670Mycobacterium leprae TN, complete genome01233BLASTN svgBLASTP svg
NC_011896:26609692660969268009919131Mycobacterium leprae Br4923, complete genome01134BLASTN svgBLASTP svg
NC_004369:3027539*3027539305195324415Corynebacterium efficiens YS-314, complete genome5e-20107BLASTN svgBLASTP svg
NC_015052:1313311*1313311135167838368Bifidobacterium longum subsp. infantis 157F, complete genome1e-1489.7BLASTN svgBLASTP svg