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Query: NC_011896:3204579 Mycobacterium leprae Br4923, complete genome

Start: 3204579, End: 3232442, Length: 27864

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_002677:32047103204710323257327864Mycobacterium leprae TN, complete genome033330BLASTN svgBLASTP svg
NC_020133:14279014279016797725188Mycobacterium liflandii 128FXT, complete genome01092BLASTN svgBLASTP svg
NC_011896:30405003040500306213921640Mycobacterium leprae Br4923, complete genome2e-56228BLASTN svgBLASTP svg
NC_002677:30407113040711306032819618Mycobacterium leprae TN, complete genome2e-56228BLASTN svgBLASTP svg
NC_013446:32090003209000323064521646Comamonas testosteroni CNB-2, complete genome2e-53218BLASTN svgBLASTP svg
NC_018681:9262000*9262000929365331654Nocardia brasiliensis ATCC 700358 chromosome, complete genome1e-45192BLASTN svgBLASTP svg
NC_008340:13036071303607132215618550Alkalilimnicola ehrlichei MLHE-1, complete genome4e-18101BLASTN svgBLASTP svg
NC_012560:2906459*2906459292809921641Azotobacter vinelandii DJ, complete genome2e-1799.6BLASTN svgBLASTP svg
NC_021150:2906471*2906471292809921629Azotobacter vinelandii CA6, complete genome2e-1799.6BLASTN svgBLASTP svg
NC_002939:1601706*1601706162134919644Geobacter sulfurreducens PCA, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_014355:78153778153780712925593Candidatus Nitrospira defluvii, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_013162:11305541130554115096920416Capnocytophaga ochracea DSM 7271, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_002946:10201751020175106499344819Neisseria gonorrhoeae FA 1090, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_007517:1515493*1515493153676021268Geobacter metallireducens GS-15, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_013169:20450002045000206559920600Kytococcus sedentarius DSM 20547, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_008699:4922465*4922465494869426230Nocardioides sp. JS614, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_004369:2968251*2968251300684438594Corynebacterium efficiens YS-314, complete genome3e-0661.9BLASTN svgBLASTP svg