Query: NC_011896:2502000 Mycobacterium leprae Br4923, complete genome
Start: 2502000, End: 2521875, Length: 19876
Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_002677:2500000* | 2500000 | 2522099 | 22100 | Mycobacterium leprae TN, complete genome | 0 | 39330 | BLASTN svg | BLASTP svg |
NC_002944:865425* | 865425 | 899160 | 33736 | Mycobacterium avium subsp. paratuberculosis K-10, complete genome | 8e-28 | 133 | BLASTN svg | BLASTP svg |
NC_010612:5653031 | 5653031 | 5673174 | 20144 | Mycobacterium marinum M, complete genome | 7e-25 | 123 | BLASTN svg | BLASTP svg |
NC_010612:5626259* | 5626259 | 5645099 | 18841 | Mycobacterium marinum M, complete genome | 7e-25 | 123 | BLASTN svg | BLASTP svg |
NC_009142:827912* | 827912 | 849126 | 21215 | Saccharopolyspora erythraea NRRL 2338, complete genome | 3e-21 | 111 | BLASTN svg | BLASTP svg |
NC_018681:867230* | 867230 | 901730 | 34501 | Nocardia brasiliensis ATCC 700358 chromosome, complete genome | 4e-20 | 107 | BLASTN svg | BLASTP svg |
NC_013159:3554389* | 3554389 | 3573622 | 19234 | Saccharomonospora viridis DSM 43017, complete genome | 2e-19 | 105 | BLASTN svg | BLASTP svg |
NC_015683:732668* | 732668 | 755009 | 22342 | Corynebacterium ulcerans BR-AD22 chromosome, complete genome | 2e-16 | 95.6 | BLASTN svg | BLASTP svg |
NC_002935:781172* | 781172 | 804705 | 23534 | Corynebacterium diphtheriae NCTC 13129, complete genome | 2e-16 | 95.6 | BLASTN svg | BLASTP svg |
NC_015673:397947* | 397947 | 424384 | 26438 | Corynebacterium resistens DSM 45100 chromosome, complete genome | 3e-15 | 91.7 | BLASTN svg | BLASTP svg |
NC_007164:511171* | 511171 | 537690 | 26520 | Corynebacterium jeikeium K411, complete genome | 3e-15 | 91.7 | BLASTN svg | BLASTP svg |
NC_013595:9547254* | 9547254 | 9578639 | 31386 | Streptosporangium roseum DSM 43021, complete genome | 1e-14 | 89.7 | BLASTN svg | BLASTP svg |
NC_012590:850130* | 850130 | 873825 | 23696 | Corynebacterium aurimucosum ATCC 700975, complete genome | 4e-14 | 87.7 | BLASTN svg | BLASTP svg |
NC_010545:1781393* | 1781393 | 1807973 | 26581 | Corynebacterium urealyticum DSM 7109, complete genome | 6e-13 | 83.8 | BLASTN svg | BLASTP svg |
NC_014815:841484* | 841484 | 898099 | 56616 | Micromonospora sp. L5 chromosome, complete genome | 2e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_014391:621062* | 621062 | 644689 | 23628 | Micromonospora aurantiaca ATCC 27029 chromosome, complete genome | 2e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_013174:2163947* | 2163947 | 2182019 | 18073 | Jonesia denitrificans DSM 20603, complete genome | 6e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_013170:311045* | 311045 | 353035 | 41991 | Cryptobacterium curtum DSM 15641, complete genome | 6e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_014151:856354* | 856354 | 881915 | 25562 | Cellulomonas flavigena DSM 20109 chromosome, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_015514:3508022* | 3508022 | 3535071 | 27050 | Cellulomonas fimi ATCC 484 chromosome, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_015671:557720* | 557720 | 577614 | 19895 | Cellvibrio gilvus ATCC 13127 chromosome, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_019673:8161242* | 8161242 | 8187342 | 26101 | Saccharothrix espanaensis DSM 44229 complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_013510:991827* | 991827 | 1012599 | 20773 | Thermomonospora curvata DSM 43183, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_003888:3602753 | 3602753 | 3626462 | 23710 | Streptomyces coelicolor A3(2), complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_003155:4592000 | 4592000 | 4636144 | 44145 | Streptomyces avermitilis MA-4680, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_006361:714944 | 714944 | 733784 | 18841 | Nocardia farcinica IFM 10152, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |