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Query: NC_011896:2502000 Mycobacterium leprae Br4923, complete genome

Start: 2502000, End: 2521875, Length: 19876

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_002677:2500000*2500000252209922100Mycobacterium leprae TN, complete genome039330BLASTN svgBLASTP svg
NC_002944:865425*86542589916033736Mycobacterium avium subsp. paratuberculosis K-10, complete genome8e-28133BLASTN svgBLASTP svg
NC_010612:56530315653031567317420144Mycobacterium marinum M, complete genome7e-25123BLASTN svgBLASTP svg
NC_010612:5626259*5626259564509918841Mycobacterium marinum M, complete genome7e-25123BLASTN svgBLASTP svg
NC_009142:827912*82791284912621215Saccharopolyspora erythraea NRRL 2338, complete genome3e-21111BLASTN svgBLASTP svg
NC_018681:867230*86723090173034501Nocardia brasiliensis ATCC 700358 chromosome, complete genome4e-20107BLASTN svgBLASTP svg
NC_013159:3554389*3554389357362219234Saccharomonospora viridis DSM 43017, complete genome2e-19105BLASTN svgBLASTP svg
NC_015683:732668*73266875500922342Corynebacterium ulcerans BR-AD22 chromosome, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_002935:781172*78117280470523534Corynebacterium diphtheriae NCTC 13129, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_015673:397947*39794742438426438Corynebacterium resistens DSM 45100 chromosome, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_007164:511171*51117153769026520Corynebacterium jeikeium K411, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_013595:9547254*9547254957863931386Streptosporangium roseum DSM 43021, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_012590:850130*85013087382523696Corynebacterium aurimucosum ATCC 700975, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_010545:1781393*1781393180797326581Corynebacterium urealyticum DSM 7109, complete genome6e-1383.8BLASTN svgBLASTP svg
NC_014815:841484*84148489809956616Micromonospora sp. L5 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_014391:621062*62106264468923628Micromonospora aurantiaca ATCC 27029 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_013174:2163947*2163947218201918073Jonesia denitrificans DSM 20603, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_013170:311045*31104535303541991Cryptobacterium curtum DSM 15641, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_014151:856354*85635488191525562Cellulomonas flavigena DSM 20109 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_015514:3508022*3508022353507127050Cellulomonas fimi ATCC 484 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_015671:557720*55772057761419895Cellvibrio gilvus ATCC 13127 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_019673:8161242*8161242818734226101Saccharothrix espanaensis DSM 44229 complete genome4e-0867.9BLASTN svgBLASTP svg
NC_013510:991827*991827101259920773Thermomonospora curvata DSM 43183, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_003888:36027533602753362646223710Streptomyces coelicolor A3(2), complete genome2e-0661.9BLASTN svgBLASTP svg
NC_003155:45920004592000463614444145Streptomyces avermitilis MA-4680, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_006361:71494471494473378418841Nocardia farcinica IFM 10152, complete genome9e-0660BLASTN svgBLASTP svg