Some Help

Query: NC_011896:563641:566066 Mycobacterium leprae Br4923, complete genome

Start: 566066, End: 566848, Length: 783

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002677:563500:566057566057566839783Mycobacterium leprae TN, complete genomehypothetical protein3e-126451
NC_019673:189487:189487189487190329843Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein2e-41169
NC_018750:1591895:160375316037531604526774Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein6e-38157
NC_017093:1411532:143141014314101432177768Actinoplanes missouriensis 431, complete genomehypothetical protein3e-26119
NC_010321:947233:961528961528962283756Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completehypothetical protein2e-22105
NC_014964:923681:953721953721954476756Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completehypothetical protein2e-22105
NC_010320:1860801:186355918635591864314756Thermoanaerobacter sp. X514 chromosome, complete genomehypothetical protein3e-2099
NC_014538:1075720:109003010900301090785756Thermoanaerobacter sp. X513 chromosome, complete genomehypothetical protein3e-2099
NC_013757:3613438:363988436398843640639756Geodermatophilus obscurus DSM 43160, complete genomeprotein of unknown function DUF811e-1480.1
NC_008686:1383891:142917114291711429911741Paracoccus denitrificans PD1222 chromosome 1, complete sequencehypothetical protein2e-1376.3
NC_008314:1202963:121184912118491212616768Ralstonia eutropha H16 chromosome 2, complete sequencehypothetical protein1e-1170.5
NC_008314:477722:490069490069490824756Ralstonia eutropha H16 chromosome 2, complete sequencepredicted permease2e-1169.3
NC_018681:5490963:552283355228335523429597Nocardia brasiliensis ATCC 700358 chromosome, complete genomehypothetical protein3e-1169.3
NC_011831:1336779:134255113425511343312762Chloroflexus aggregans DSM 9485, complete genomeprotein of unknown function DUF812e-1066.6
NC_008061:2193000:219459521945952195332738Burkholderia cenocepacia AU 1054 chromosome 2, complete sequenceprotein of unknown function DUF812e-0756.6
NC_008543:61000:744417444175178738Burkholderia cenocepacia HI2424 chromosome 2, complete sequenceprotein of unknown function DUF812e-0756.6
NC_014209:1392115:140530214053021405646345Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,protein of unknown function DUF819e-0753.9