Pre_GI: BLASTP Hits

Some Help

Query: NC_011896:363448:382851 Mycobacterium leprae Br4923, complete genome

Start: 382851, End: 383558, Length: 708

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002677:363432:382835382835383542708Mycobacterium leprae TN, complete genomethiamine-phosphate pyrophosphorylase4e-100363
NC_017243:349144:352639352639353340702Brachyspira intermedia PWS/A chromosome, complete genomethiamine-phosphate pyrophosphorylase8e-1270.9
NC_014828:1632000:163402616340261634691666Ethanoligenens harbinense YUAN-3 chromosome, complete genomethiamine-phosphate pyrophosphorylase9e-1270.5
NC_010175:448020:472705472705473355651Chloroflexus aurantiacus J-10-fl, complete genomethiamine-phosphate pyrophosphorylase1e-1170.5
NC_012032:448161:472847472847473497651Chloroflexus sp. Y-400-fl, complete genomethiamine-phosphate pyrophosphorylase1e-1170.5
NC_013790:2337000:235244423524442353103660Methanobrevibacter ruminantium M1 chromosome, complete genomethiamine monophosphate synthase ThiE2e-1066.2
NC_011988:924721:929839929839930450612Agrobacterium vitis S4 chromosome 2, complete genomethiamine-phosphate pyrophosphorylase protein2e-0962.8
NC_007503:1111457:112691811269181127565648Carboxydothermus hydrogenoformans Z-2901, complete genomethiamine-phosphate pyrophosphorylase3e-0962.4
NC_014831:2201246:222146822214682222166699Thermaerobacter marianensis DSM 12885 chromosome, complete genomethiamine-phosphate diphosphorylase4e-0962
NC_013741:687546:692257692257692871615Archaeoglobus profundus DSM 5631, complete genomethiamine-phosphate pyrophosphorylase4e-0858.2
NC_016048:2907702:293108029310802931718639Oscillibacter valericigenes Sjm18-20, complete genomethiamine-phosphate pyrophosphorylase1e-0757
NC_012489:4336790:4356351435635143578321482Gemmatimonas aurantiaca T-27, complete genomethiamine-phosphate pyrophosphorylase/phosphomethylpyrimidine kinase2e-0755.8
NC_015942:3185193:318998031899803190633654Acidithiobacillus ferrivorans SS3 chromosome, complete genomeThiamine-phosphate pyrophosphorylase3e-0755.5
NC_010337:98974:1000791000791014431365Heliobacterium modesticaldum Ice1, complete genomethiamine monophosphate synthase, putative5e-0754.7
NC_014314:238043:238043238043238684642Dehalogenimonas lykanthroporepellens BL-DC-9 chromosome, completethiamine-phosphate pyrophosphorylase6e-0754.3
NC_013174:1254874:125564412556441256390747Jonesia denitrificans DSM 20603, complete genomeThiamine-phosphate diphosphorylase1e-0653.5