Pre_GI: BLASTP Hits

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Query: NC_011896:363448:381671 Mycobacterium leprae Br4923, complete genome

Start: 381671, End: 382693, Length: 1023

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002677:363432:3816553816553826771023Mycobacterium leprae TN, complete genomeputative oxidoreductase5e-173607
NC_000918:465627:4835834835834846441062Aquifex aeolicus VF5, complete genomehypothetical protein6e-30131
NC_013715:1907503:1912622191262219137041083Rothia mucilaginosa DY-18, complete genomeglycine/D-amino acid oxidase2e-20100
NC_010730:741842:7791637791637802601098Sulfurihydrogenibium sp. YO3AOP1, complete genomeglycine oxidase ThiO4e-1892.4
NC_011988:924721:927881927881928873993Agrobacterium vitis S4 chromosome 2, complete genomeglycine oxidase ThiO1e-1791.3
NC_005125:2269343:2288011228801122890661056Gloeobacter violaceus PCC 7421, complete genomeprobable oxidoreductase3e-1789.7
NC_011901:3363500:3380830338083033819481119Thioalkalivibrio sulfidophilus HL-EbGr7 chromosome, completeglycine oxidase ThiO2e-1687
NC_017030:4588167:4606880460688046079951116Corallococcus coralloides DSM 2259 chromosome, complete genomeglycine oxidase ThiO1e-1584.3
NC_003295:112778:1292151292151303541140Ralstonia solanacearum GMI1000, complete genomePUTATIVE D-AMINO ACID OXIDASE FLAVOPROTEIN OXIDOREDUCTASE7e-1375.1
NC_021171:1689518:1704959170495917060681110Bacillus sp. 1NLA3E, complete genomeFAD-dependent glycine oxidase ThiO8e-1374.7
NC_019896:2805098:2830603283060328317121110Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completeGlycine oxidase8e-1374.7
NC_014831:2201246:2223388222338822245871200Thermaerobacter marianensis DSM 12885 chromosome, complete genomeglycine oxidase ThiO1e-1170.9
NC_009434:1068281:108088810808881081748861Pseudomonas stutzeri A1501, complete genomeoxidoreductase, FAD-binding1e-1067.8
NC_005861:2120633:2121400212140021224041005Candidatus Protochlamydia amoebophila UWE25, complete genomehypothetical protein2e-1066.6
NC_007516:2277910:2302913230291323039801068Synechococcus sp. CC9605, complete genomeputative thiamine biosynthesis oxidoreductase5e-1065.5
NC_009482:2051890:2068353206835320694951143Synechococcus sp. RCC307 chromosome, complete genomeglycine/D-amino acid oxidase family protein8e-1065.1
NC_015740:926920:9394409394409405371098Pseudomonas stutzeri ATCC 17588 = LMG 11199 chromosome, completeFAD-binding oxidoreductase1e-0964.7
NC_013523:2560000:2574631257463125757641134Sphaerobacter thermophilus DSM 20745 chromosome 1, complete genomeFAD dependent oxidoreductase1e-0964.7
NC_015942:1711026:1727085172708517281761092Acidithiobacillus ferrivorans SS3 chromosome, complete genomeFAD dependent oxidoreductase1e-0964.3
NC_015410:1144272:1156632115663211576961065Pseudomonas mendocina NK-01 chromosome, complete genomeglycine oxidase ThiO1e-0963.9
NC_005945:754517:7561427561427572511110Bacillus anthracis str. Sterne, complete genomeglycine oxidase2e-0963.9
NC_009481:2204629:2206182220618222073091128Synechococcus sp. WH 7803 chromosome, complete genomeglycine/D-amino acid oxidase family protein4e-0962.4
NC_014394:2228470:2232697223269722337611065Gallionella capsiferriformans ES-2 chromosome, complete genomeglycine oxidase ThiO6e-0962
NC_008027:5842740:5844182584418258454321251Pseudomonas entomophila L48, complete genomehydrogen cyanide synthase HcnC1e-0861.2
NC_009439:1075170:1088508108850810895931086Pseudomonas mendocina ymp, complete genomeglycine oxidase ThiO1e-0861.2
NC_008260:497855:5104435104435114801038Alcanivorax borkumensis SK2, complete genomeoxidoreductase2e-0860.5
NC_015556:4118304:4123843412384341249161074Pseudomonas fulva 12-X chromosome, complete genomeglycine oxidase ThiO3e-0859.7
NC_018080:5192264:5197779519777951988551077Pseudomonas aeruginosa DK2 chromosome, complete genomeD-amino acid oxidase8e-0858.2
NC_008463:5364428:5368835536883553699291095Pseudomonas aeruginosa UCBPP-PA14, complete genomeputative Glycine/D-amino acid oxidases1e-0758.2
NC_007492:3954345:3993694399369439949531260Pseudomonas fluorescens PfO-1, complete genomeFAD dependent oxidoreductase4e-0755.8