Pre_GI: BLASTP Hits

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Query: NC_011896:3252925:4435 Mycobacterium leprae Br4923, complete genome

Start: 4435, End: 5004, Length: 570

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002677:1:443544355004570Mycobacterium leprae TN, complete genomehypothetical protein5e-96349
NC_011896:1:443544355004570Mycobacterium leprae Br4923, complete genomehypothetical protein5e-96349
NC_002677:3253057:443544355004570Mycobacterium leprae TN, complete genomehypothetical protein5e-96349
NC_017186:3694:596759676470504Amycolatopsis mediterranei S699 chromosome, complete genomehypothetical protein4e-43174
NC_014318:3691:596759676470504Amycolatopsis mediterranei U32 chromosome, complete genomehypothetical protein4e-43174
NC_015564:4727630:481548155312498Amycolicicoccus subflavus DQS3-9A1 chromosome, complete genomehypothetical protein1e-42172
NC_015312:1:531153115907597Pseudonocardia dioxanivorans CB1190 chromosome, complete genomehypothetical protein1e-38159
NC_013093:1:603160316462432Actinosynnema mirum DSM 43827, complete genomeprotein of unknown function DUF7217e-33139
NC_011886:4376261:548254826039558Arthrobacter chlorophenolicus A6, complete genomeprotein of unknown function DUF7216e-29126
NC_014550:3839389:459845985155558Arthrobacter arilaitensis Re117, complete genomehypothetical protein2e-27121
NC_008711:4579997:531853185872555Arthrobacter aurescens TC1, complete genomeputative protein of unknown function (DUF721)1e-26119
NC_008541:4679022:526352635820558Arthrobacter sp. FB24 chromosome 1, complete sequenceprotein of unknown function DUF7219e-27119
NC_012803:3691:489848985461564Micrococcus luteus NCTC 2665, complete genomepredicted RNA-binding protein containing Zn ribbon2e-26118
NC_006085:2544421:538953895997609Propionibacterium acnes KPA171202, complete genomehypothetical protein1e-25115
NC_014039:2479500:540054005993594Propionibacterium acnes SK137 chromosome, complete genomehypothetical protein1e-25115
NC_013521:4240468:571557156305591Sanguibacter keddieii DSM 10542, complete genomepredicted RNA-binding protein containing Zn ribbon8e-25113
NC_014830:4012999:639963996932534Intrasporangium calvum DSM 43043 chromosome, complete genomeprotein of unknown function DUF7212e-24112
NC_015145:4232283:570157016261561Arthrobacter phenanthrenivorans Sphe3 chromosome, complete genomeRNA-binding protein containing Zn ribbon4e-24110
NC_014151:4106624:577957796402624Cellulomonas flavigena DSM 20109 chromosome, complete genomeprotein of unknown function DUF7213e-23107
NC_008578:2431074:420242024696495Acidothermus cellulolyticus 11B, complete genomeprotein of unknown function DUF7213e-22104
NC_006087:1:531453145790477Leifsonia xyli subsp. xyli str. CTCB07, complete genomehypothetical protein4e-22104
NC_015125:1597600:159975215997521600240489Microbacterium testaceum StLB037, complete genomeZn-ribbon-containing, possibly RNA-binding protein and truncated derivatives9e-22103
NC_015953:3684065:368650336865033687063561Streptomyces sp. SirexAA-E chromosome, complete genomehypothetical protein2e-2099
NC_014218:4424:442444245008585Arcanobacterium haemolyticum DSM 20595 chromosome, complete genomeprotein of unknown function DUF7214e-1994.4
NC_018750:3964784:396707839670783967641564Streptomyces venezuelae ATCC 10712, complete genomepossible RNA-binding protein3e-1891.7
NC_013510:1:644464446983540Thermomonospora curvata DSM 43183, complete genomeprotein of unknown function DUF7219e-1889.7
NC_007164:2446879:486348635390528Corynebacterium jeikeium K411, complete genomehypothetical protein1e-1789.7
NC_013595:10329633:704770477667621Streptosporangium roseum DSM 43021, complete genomeZn-ribbon-containing possibly RNA-binding protein and truncated derivatives-like protein2e-1788.6
NC_015673:1:496549655504540Corynebacterium resistens DSM 45100 chromosome, complete genomehypothetical protein6e-1580.5
NC_007333:1:611161116632522Thermobifida fusca YX, complete genomehypothetical protein7e-1580.5
NC_007333:3626510:611161116632522Thermobifida fusca YX, complete genomehypothetical protein7e-1580.5
NC_003888:4251867:426587342658734266445573Streptomyces coelicolor A3(2), complete genomehypothetical protein3e-1271.6
NC_010816:1660066:166233716623371662807471Bifidobacterium longum DJO10A, complete genomeZn-ribbon-containing RNA-binding protein2e-1168.9
NC_014656:1634397:163666816366681637138471Bifidobacterium longum subsp. longum BBMN68 chromosome, completezn-ribbon-containing RNA-binding protein2e-1168.6
NC_015067:2371428:462646265096471Bifidobacterium longum subsp. longum JCM 1217, complete genomehypothetical protein2e-1168.6
NC_004307:1620500:162067016206701621140471Bifidobacterium longum NCC2705, complete genomehypothetical protein similar to orf 192 of M. smegmatis3e-1168.2
NC_017221:2268276:226827622682762268746471Bifidobacterium longum subsp. longum KACC 91563 chromosome,hypothetical protein1e-1066.6
NC_015052:2383865:462646265096471Bifidobacterium longum subsp. infantis 157F, complete genomehypothetical protein1e-1066.6
NC_014210:5752651:696069607313354Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,protein of unknown function DUF7212e-1065.9
NC_010572:8493946:850739285073928508267876Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative Tra3-like protein4e-0651.2
NC_010572:33724:376633766338538876Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative Tra3-like protein4e-0651.2
NC_014761:1981435:199800619980061998815810Oceanithermus profundus DSM 14977 chromosome, complete genomehypothetical protein7e-0650.4