Pre_GI: BLASTP Hits

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Query: NC_011896:3252925:3252925 Mycobacterium leprae Br4923, complete genome

Start: 3252925, End: 3256545, Length: 3621

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002677:3253057:3253057325305732566773621Mycobacterium leprae TN, complete genomepossible conserved membrane protein02128
NC_007164:2446879:2446879244687924507903912Corynebacterium jeikeium K411, complete genomehypothetical protein1e-105385
NC_008705:27434:5444054440563111872Mycobacterium sp. KMS, complete genomeconserved hypothetical protein3e-87324
NC_008146:20047:4710047100489711872Mycobacterium sp. MCS, complete genomehypothetical protein3e-87324
NC_007333:3626510:3628986362898636308691884Thermobifida fusca YX, complete genomevirulence factor MVIN-like4e-37157
NC_014210:5752651:5752651575265157545161866Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,integral membrane protein MviN5e-33144
NC_013929:5135285:5154176515417651564072232Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein6e-32140
NC_003888:4251867:4285147428514742875822436Streptomyces coelicolor A3(2), complete genometransmembrane protein2e-29132
NC_003155:5253923:5271112527111252733792268Streptomyces avermitilis MA-4680, complete genometransmembrane protein2e-28129
NC_021177:4041915:4043790404379040459552166Streptomyces fulvissimus DSM 40593, complete genomeTransmembrane protein5e-27124
NC_015953:3684065:3705433370543337075952163Streptomyces sp. SirexAA-E chromosome, complete genomeintegral membrane protein MviN1e-26122
NC_016114:3655005:3669315366931536714742160Streptomyces flavogriseus ATCC 33331 chromosome, complete genomeintegral membrane protein MviN5e-25117
NC_021064:31816:3307133071349181848Propionibacterium avidum 44067, complete genomemembrane protein, MviN-like protein1e-23113
NC_015145:4232283:4234558423455842367622205Arthrobacter phenanthrenivorans Sphe3 chromosome, complete genomeintegral membrane protein MviN9e-1790.1
NC_014638:2199799:2202075220207522065114437Bifidobacterium bifidum PRL2010 chromosome, complete genomehypothetical protein1e-1689.7
NC_008541:4679022:4681264468126446833902127Arthrobacter sp. FB24 chromosome 1, complete sequenceintegral membrane protein MviN2e-1689.4
NC_018531:4718904:4718904471890447209192016Arthrobacter sp. Rue61a chromosome, complete genomeintegral membrane protein MviN4e-1688.2
NC_014616:2172025:2174301217430121787374437Bifidobacterium bifidum S17 chromosome, complete genomehypothetical protein6e-1687.4
NC_011886:4376261:4378545437854543806922148Arthrobacter chlorophenolicus A6, complete genomeintegral membrane protein MviN7e-1687.4
NC_008711:4579997:4579997457999745819521956Arthrobacter aurescens TC1, complete genomeintegral membrane protein MviN7e-1687.4
NC_011593:2819230:2821425282142528252973873Bifidobacterium longum subsp. infantis ATCC 15697 chromosome,virulence factor MVIN family protein2e-1482.8
NC_017219:2815225:2817426281742628212983873Bifidobacterium longum subsp. infantis ATCC 15697, complete genomehypothetical protein2e-1482.8
NC_014169:2466442:2466442246644224703143873Bifidobacterium longum subsp. longum JDM301 chromosome, completevirulence factor MVIN family protein4e-1481.6
NC_017218:2313245:2316363231636323201333771Bifidobacterium breve ACS-071-V-Sch8b chromosome, complete genomeputative integral membrane protein MviN2e-1379
NC_013174:2712000:2736375273637527380331659Jonesia denitrificans DSM 20603, complete genomeintegral membrane protein MviN1e-1276.6
NC_014550:3839389:3840044384004438416751632Arthrobacter arilaitensis Re117, complete genomeMviN-like protein7e-1273.9
NC_004307:1620500:1635575163557516373021728Bifidobacterium longum NCC2705, complete genomeconserved hypothetical membrane protein in MviN family5e-1171.2
NC_010816:1660066:1677243167724316789701728Bifidobacterium longum DJO10A, complete genomeHypothetical membrane protein5e-1171.2
NC_015067:2371428:2373626237362623753531728Bifidobacterium longum subsp. longum JCM 1217, complete genomehypothetical protein5e-1171.2
NC_018720:2138180:2138180213818021424034224Bifidobacterium asteroides PRL2011 chromosome, complete genomevirulence factor MVIN family protein8e-1170.5
NC_014656:1634397:1651576165157616533031728Bifidobacterium longum subsp. longum BBMN68 chromosome, completemvin1e-1070.1
NC_018080:5192264:5212249521224952137871539Pseudomonas aeruginosa DK2 chromosome, complete genomevirulence factor, membrane protein3e-1068.6
NC_008463:5364428:5383305538330553848431539Pseudomonas aeruginosa UCBPP-PA14, complete genomeputative virulence factor, membrane protein3e-1068.6
NC_010465:2383219:2395386239538623970141629Yersinia pseudotuberculosis YPIII, complete genomeintegral membrane protein MviN6e-0964.3
NC_008800:2592500:2602499260249926040341536Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein3e-0862
NC_010943:1332243:1368167136816713697861620Stenotrophomonas maltophilia K279a, complete genomeputative transmembrane virulence factor MmviN3e-0861.6
NC_007645:6049340:6071246607124660728141569Hahella chejuensis KCTC 2396, complete genomeintegral membrane protein MviN4e-0861.6
NC_009708:2347350:2358289235828923598241536Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeintegral membrane protein MviN5e-0860.8
NC_006155:2378526:2383495238349523850301536Yersinia pseudotuberculosis IP 32953, complete genomevirulence factor mviN, possible MOP Superfamliy efflux pump8e-0860.5
NC_010634:2297000:2301404230140423029391536Yersinia pseudotuberculosis PB1/+, complete genomeintegral membrane protein MviN9e-0860.1
NC_008149:1718000:1723042172304217245771536Yersinia pestis Nepal516, complete genomemembrane protein2e-0759.3
NC_010159:2546590:2558924255892425604591536Yersinia pestis Angola, complete genomeintegral membrane protein MviN2e-0759.3
NC_005810:2091930:2096856209685620983911536Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-0759.3
NC_003143:2309500:2314426231442623159611536Yersinia pestis CO92, complete genomehypothetical protein2e-0759.3
NC_004088:2491303:2503559250355925050941536Yersinia pestis KIM, complete genomevirulence factor2e-0759.3
NC_008150:1593500:1598714159871416002491536Yersinia pestis Antiqua, complete genomehypothetical protein2e-0759.3
NC_009381:1205900:1218072121807212196071536Yersinia pestis Pestoides F chromosome, complete genomemembrane protein2e-0759.3
NC_014029:2285323:2297547229754722990821536Yersinia pestis Z176003 chromosome, complete genomehypothetical protein2e-0759.3
NC_017154:2306421:2311347231134723128821536Yersinia pestis D106004 chromosome, complete genomehypothetical protein2e-0759.3
NC_017160:2212806:2225046222504622265811536Yersinia pestis D182038 chromosome, complete genomehypothetical protein2e-0759.3
NC_017168:3433804:3446012344601234475471536Yersinia pestis A1122 chromosome, complete genomevirulence factor MviN2e-0759.3
NC_017265:2213500:2225222222522222267571536Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative inner membrane protein2e-0759.3
NC_010995:3821327:3844192384419238457961605Cellvibrio japonicus Ueda107, complete genomeintegral membrane protein MviN6e-0654.3
NC_015677:2939301:2964735296473529663001566Ramlibacter tataouinensis TTB310 chromosome, complete genomevirulence factor6e-0654.3
NC_006677:2042387:2057316205731620588721557Gluconobacter oxydans 621H, complete genomeVirulence factor MviN1e-0553.5