Some Help

Query: NC_011896:3252925:3250535 Mycobacterium leprae Br4923, complete genome

Start: 3250535, End: 3252928, Length: 2394

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002677:3253057:3250667325066732530602394Mycobacterium leprae TN, complete genomeputative secreted protein.01457
NC_012590:2755429:2772211277221127743522142Corynebacterium aurimucosum ATCC 700975, complete genomeputative membrane protein4e-30134
NC_016114:3655005:3666968366696836692652298Streptomyces flavogriseus ATCC 33331 chromosome, complete genomehypothetical protein6e-1273.6
NC_018750:3988196:3988196398819639905652370Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein1e-1069.3
NC_013929:5135285:5156455515645551588602406Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein1e-1069.3
NC_015953:3684065:3707645370764537099422298Streptomyces sp. SirexAA-E chromosome, complete genomehypothetical protein1e-1068.9
NC_003888:4251867:4287627428762742899902364Streptomyces coelicolor A3(2), complete genomehypothetical protein1e-0965.9
NC_003155:5253923:5268648526864852710652418Streptomyces avermitilis MA-4680, complete genomehypothetical protein1e-0862.4
NC_021177:4041915:4046006404600640483002295Streptomyces fulvissimus DSM 40593, complete genomehypothetical protein3e-0861.2