Pre_GI: BLASTP Hits

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Query: NC_011896:2775000:2779402 Mycobacterium leprae Br4923, complete genome

Start: 2779402, End: 2781600, Length: 2199

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013093:2471574:2482116248211624849862871Actinosynnema mirum DSM 43827, complete genometranscriptional regulator, LuxR family2e-0654.7
NC_011983:1746000:1755002175500217580283027Agrobacterium radiobacter K84 chromosome 2, complete genomeadenylate/guanylate cyclase protein1e-30135
NC_013851:2441407:244518524451852446135951Allochromatium vinosum DSM 180 chromosome, complete genomeadenylate/guanylate cyclase2e-1688.2
NC_013857:478000:4944164944164965542139Azospirillum sp. B510 plasmid pAB510c, complete sequenceguanylate cyclase6e-1170.1
NC_017188:2221705:223159922315992232360762Bacillus amyloliquefaciens TA208 chromosome, complete genomeadenylate/guanylate cyclase6e-0756.6
NC_017191:2223740:223363422336342234356723Bacillus amyloliquefaciens XH7 chromosome, complete genomeadenylate/guanylate cyclase3e-0654.7
NC_004463:2475428:2477926247792624795091584Bradyrhizobium japonicum USDA 110, complete genometwo-component hybrid sensor and regulator1e-0965.9
NC_017249:3267500:3283958328395832855651608Bradyrhizobium japonicum USDA 6, complete genomehypothetical protein3e-0964.3
NC_017082:532000:5760965760965795273432Bradyrhizobium sp. S23321, complete genomeputative adenylate cyclase2e-47191
NC_017082:5925357:5943299594329959444891191Bradyrhizobium sp. S23321, complete genomeputative adenylate cyclase7e-0963.2
NC_017082:6444522:6444522644452264460841563Bradyrhizobium sp. S23321, complete genomeputative adenylate/guanylate cyclase1e-1792
NC_013131:8029621:8032295803229580353123018Catenulispora acidiphila DSM 44928, complete genometranscriptional regulator, LuxR family4e-1067.4
NC_017030:158947:1769101769101804583549Corallococcus coralloides DSM 2259 chromosome, complete genomeserine/threonine protein kinase2e-1068.2
NC_007164:2261644:2277364227736422788961533Corynebacterium jeikeium K411, complete genomeadenylate cyclase, putative5e-1273.6
NC_012704:2296500:2298522229852223000511530Corynebacterium kroppenstedtii DSM 44385, complete genomeadenylate cyclase8e-1169.7
NC_015723:430165:4335914335914375383948Cupriavidus necator N-1 chromosome 2, complete sequenceadenylate/guanylate cyclase3e-51204
NC_015723:2550000:2561578256157825628311254Cupriavidus necator N-1 chromosome 2, complete sequenceadenylate cyclase Cya7e-1583.2
NC_015723:280368:3037783037783092855508Cupriavidus necator N-1 chromosome 2, complete sequencenodulation protein NodV8e-0756.2
NC_015727:1294532:1301687130168713029251239Cupriavidus necator N-1 plasmid BB1p, complete sequenceadenylate cyclase Cya1e-1379
NC_015388:2499187:2499187249918725014392253Desulfobacca acetoxidans DSM 11109 chromosome, complete genomeadenylate/guanylate cyclase with Chase sensor1e-20102
NC_015388:89000:1031631031631042361074Desulfobacca acetoxidans DSM 11109 chromosome, complete genomeadenylate/guanylate cyclase8e-1479.3
NC_012108:2975676:2987453298745329910043552Desulfobacterium autotrophicum HRM2, complete genomeputative 2-component fusion protein (N: adenylate cyclase-C:G-protein signalling modulator)4e-55216
NC_016803:593484:6152656152656174722208Desulfovibrio desulfuricans ND132 chromosome, complete genomeadenylate/guanylate cyclase with Chase sensor1e-1379
NC_014836:223013:2349762349762372372262Desulfurispirillum indicum S5 chromosome, complete genomeadenylyl cyclase class-3/4/guanylyl cyclase4e-1480.5
NC_013037:1015210:1015210101521010208255616Dyadobacter fermentans DSM 18053, complete genomeATP-binding region ATPase domain protein3e-1377.4
NC_010814:2074266:2090490209049020925802091Geobacter lovleyi SZ, complete genomeadenylate/guanylate cyclase with Chase sensor1e-1689.4
NC_013440:5543667:5561922556192255661244203Haliangium ochraceum DSM 14365, complete genomeserine/threonine protein kinase2e-1172
NC_013440:1879306:1879306187930618833074002Haliangium ochraceum DSM 14365, complete genomeserine/threonine protein kinase2e-0758.5
NC_015510:3834282:3837043383704338410654023Haliscomenobacter hydrossis DSM 1100 chromosome, complete genomeadenylate/guanylate cyclase6e-1480.1
NC_008789:2057368:2074161207416120760981938Halorhodospira halophila SL1, complete genomeputative adenylate/guanylate cyclase6e-1686.7
NC_011899:1926000:1939920193992019416681749Halothermothrix orenii H 168, complete genomeputative Chase2 sensor protein3e-1791.3
NC_019964:2424846:2444906244490624480793174Halovivax ruber XH-70, complete genometetratricopeptide repeat protein5e-0963.5
NC_010842:2615808:2616295261629526195493255Leptospira biflexa serovar Patoc strain 'Patoc 1 (Ames)' chromosomeAdenylate/guanylate cyclase6e-1170.1
NC_015276:2552484:2561338256133825657114374Marinomonas mediterranea MMB-1 chromosome, complete genomeserine/threonine protein kinase5e-1273.6
NC_012988:4353000:4362087436208743638111725Methylobacterium extorquens DM4, complete genomeadenylate cyclase1e-0965.9
NC_010172:3413392:3430236343023634319631728Methylobacterium extorquens PA1, complete genomeadenylyl cyclase class-3/4/guanylyl cyclase2e-0964.7
NC_011894:3578500:3580710358071035820891380Methylobacterium nodulans ORS 2060, complete genomeadenylate/guanylate cyclase5e-0757
NC_010505:4676403:4694314469431446960381725Methylobacterium radiotolerans JCM 2831, complete genomeadenylate/guanylate cyclase4e-0653.9
NC_010505:5967324:5987461598746159887261266Methylobacterium radiotolerans JCM 2831, complete genomeadenylate/guanylate cyclase1e-0552.8
NC_010511:3106418:3110909311090931125041596Methylobacterium sp. 4-46 chromosome, complete genomeadenylate/guanylate cyclase2e-1378.2
NC_010511:7024412:7057222705722270589881767Methylobacterium sp. 4-46 chromosome, complete genomeadenylate/guanylate cyclase with integral membrane sensor8e-0962.8
NC_016948:419500:4435584435584451111554Mycobacterium intracellulare MOTT-64 chromosome, complete genomeadenylate cyclase, family protein 32e-0964.7
NC_002677:2775365:2779477277947727816752199Mycobacterium leprae TN, complete genomepossible regulatory protein01366
NC_020133:2421965:2440904244090424424361533Mycobacterium liflandii 128FXT, complete genomeconserved transmembrane protein5e-0653.5
NC_010612:4679594:4681990468199046836391650Mycobacterium marinum M, complete genomeadenylate cyclase4e-0757.4
NC_008705:1537080:1540135154013515435603426Mycobacterium sp. KMS, complete genometranscriptional regulator, SARP family1e-0862.4
NC_008146:1535827:1535827153582715392523426Mycobacterium sp. MCS, complete genometranscriptional regulator, SARP family1e-0862.4
NC_017904:4203257:4213445421344542149711527Mycobacterium sp. MOTT36Y chromosome, complete genomehypothetical protein8e-0963.2
NC_008095:8837612:8850269885026988538953627Myxococcus xanthus DK 1622, complete genomeserine/threonine protein kinase3e-0654.3
NC_008609:3732192:3765140376514037705065367Pelobacter propionicus DSM 2379, complete genomePAS sensor protein1e-0965.9
NC_008313:1956500:1972200197220019736301431Ralstonia eutropha H16 chromosome 1, complete sequenceadenylate cyclase, family 33e-0964.3
NC_008313:886248:9036189036189047901173Ralstonia eutropha H16 chromosome 1, complete sequenceresponse regulator containing an adenylate cyclase effector domain2e-1378.2
NC_005241:380415:4022154022154034531239Ralstonia eutropha H16 megaplasmid pHG1, complete sequenceregulatory protein4e-1687.4
NC_007336:601190:6024096024096035961188Ralstonia eutropha JMP134 megaplasmid, complete sequenceAdenylate cyclase5e-1583.6
NC_017059:31564:5663056630589662337Rhodospirillum photometricum DSM 122, complete genomeadenylate cyclase8e-1376.3
NC_009142:6199326:6200823620082362036542832Saccharopolyspora erythraea NRRL 2338, complete genometranscriptional regulator, LuxR family2e-0655.5
NC_009142:6086000:6090748609074860943023555Saccharopolyspora erythraea NRRL 2338, complete genomehypothetical protein8e-1272.8
NC_009953:3316782:3317705331770533208603156Salinispora arenicola CNS-205 chromosome, complete genomeATPase-like protein6e-0963.2
NC_009380:1885024:1890396189039618921291734Salinispora tropica CNB-440 chromosome, complete genomeadenylyl cyclase class-3/4/guanylyl cyclase2e-1584.7
NC_018000:2964500:2972083297208329740321950Sinorhizobium fredii USDA 257 chromosome, complete genomeadenylate cyclase5e-1273.6
NC_010162:9727465:9756070975607097578151746Sorangium cellulosum 'So ce 56', complete genomehypothetical protein7e-1686.3
NC_010162:6562571:6598636659863666025233888Sorangium cellulosum 'So ce 56', complete genomeprotein kinase1e-1172.4
NC_014484:1163576:1184527118452711868902364Spirochaeta thermophila DSM 6192 chromosome, complete genomehypothetical protein3e-1894.4
NC_013947:5682895:5684186568418656868882703Stackebrandtia nassauensis DSM 44728 chromosome, complete genometranscriptional regulator, LuxR family1e-0862
NC_007516:2277910:2321887232188723238391953Synechococcus sp. CC9605, complete genomeAdenylyl cyclase class-3/4/guanylyl cyclase2e-0654.7
NC_009481:2204629:2221447222144722233091863Synechococcus sp. WH 7803 chromosome, complete genomeadenylate cyclase9e-0652.8
NC_013510:810525:8223878223878255513165Thermomonospora curvata DSM 43183, complete genomeATPase-like protein1e-0862.4
NC_014974:1076565:1105609110560911089443336Thermus scotoductus SA-01 chromosome, complete genometranscriptional activator domain-containing protein2e-1997.8
NC_017278:1720371:1720371172037117233222952Thermus sp. CCB_US3_UF1 chromosome, complete genomehypothetical protein2e-1172
NC_015385:2505977:2506466250646625093662901Treponema succinifaciens DSM 2489 chromosome, complete genomeadenylate/guanylate cyclase with Chase sensor5e-1583.6
NC_008312:4795204:4813106481310648166243519Trichodesmium erythraeum IMS101, complete genomeadenylate/guanylate cyclase2e-1585.1
NC_008312:3728329:3728329372832937319523624Trichodesmium erythraeum IMS101, complete genomeadenylate/guanylate cyclase2e-1585.1
NC_014221:3068222:3088136308813630897671632Truepera radiovictrix DSM 17093 chromosome, complete genomeadenylate/guanylate cyclase3e-32140
NC_014931:6415940:6431104643110464333562253Variovorax paradoxus EPS chromosome, complete genomeadenylate/guanylate cyclase with Chase sensor1e-1482.4
NC_012791:5496175:5509565550956555118412277Variovorax paradoxus S110 chromosome 1, complete genomeadenylate/guanylate cyclase with Chase sensor8e-1376.3