Pre_GI: BLASTP Hits

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Query: NC_011896:1716000:1734402 Mycobacterium leprae Br4923, complete genome

Start: 1734402, End: 1736336, Length: 1935

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002677:1716000:1734469173446917364031935Mycobacterium leprae TN, complete genomepossible apolipoprotein N-acyltransferase0934
NC_012943:2103662:2105791210579121085802790Mycobacterium tuberculosis KZN 1435 chromosome, complete genomepolyprenol-monophosphomannose synthase ppm12e-150533
NC_016804:2254979:2271148227114822737722625Mycobacterium bovis BCG str. Mexico chromosome, complete genomepolyprenol-monophosphomannose synthase4e-150532
NC_016768:2101751:2104045210404521066692625Mycobacterium tuberculosis KZN 4207 chromosome, complete genomepolyprenol-monophosphomannose synthase ppm14e-150532
NC_009565:2306574:2322743232274323253672625Mycobacterium tuberculosis F11, complete genomepolyprenol-monophosphomannose synthase ppm14e-150532
NC_017026:2286000:2301448230144823040752628Mycobacterium tuberculosis RGTB327 chromosome, complete genomepolyprenol-monophosphomannose synthase Ppm18e-147521
NC_018750:770500:7909757909757926571683Streptomyces venezuelae ATCC 10712, complete genomeputative polyprenol-phosphate-mannosyl transferase3e-62240
NC_013441:2788806:2807872280787228094191548Gordonia bronchialis DSM 43247, complete genomeapolipoprotein N-acyltransferase4e-61236
NC_007164:1090858:1111948111194811133751428Corynebacterium jeikeium K411, complete genomepolyprenol-phosphate-mannose synthase domain 24e-61236
NC_016800:1219121:1228688122868812302411554Corynebacterium diphtheriae BH8 chromosome, complete genomepolyprenol-phosphate-mannose synthase8e-57222
NC_016802:1186326:1199607119960712009771371Corynebacterium diphtheriae HC02 chromosome, complete genomepolyprenol-phosphate-mannose synthase2e-56221
NC_016785:1167057:1180336118033611817061371Corynebacterium diphtheriae CDCE 8392 chromosome, complete genomepolyprenol-phosphate-mannose synthase1e-56221
NC_016783:1216708:1226157122615712277101554Corynebacterium diphtheriae INCA 402 chromosome, complete genomepolyprenol-phosphate-mannose synthase1e-56221
NC_016790:1152249:1167089116708911684591371Corynebacterium diphtheriae VA01 chromosome, complete genomepolyprenol-phosphate-mannose synthase4e-56219
NC_016789:1232993:1244252124425212458111560Corynebacterium diphtheriae PW8 chromosome, complete genomepolyprenol-phosphate-mannose synthase5e-55216
NC_009380:2548878:2564312256431225659911680Salinispora tropica CNB-440 chromosome, complete genomeapolipoprotein N-acyltransferase6e-53209
NC_009953:2727669:2744288274428827459191632Salinispora arenicola CNS-205 chromosome, complete genomeapolipoprotein N-acyltransferase1e-52208
NC_015434:3507059:3524309352430935259251617Verrucosispora maris AB-18-032 chromosome, complete genomeapolipoprotein N-acyltransferase4e-52206
NC_014165:2081914:2087953208795320895061554Thermobispora bispora DSM 43833 chromosome, complete genomeapolipoprotein N-acyltransferase8e-47189
NC_009806:35990:4889648896505751680Kineococcus radiotolerans SRS30216 plasmid pKRAD01, completeapolipoprotein N-acyltransferase3e-44180
NC_014318:5183975:5201222520122252028321611Amycolatopsis mediterranei U32 chromosome, complete genomeapolipoprotein N-acyltransferase7e-43176
NC_017186:5184000:5201256520125652028541599Amycolatopsis mediterranei S699 chromosome, complete genomeapolipoprotein N-acyltransferase8e-43175
NC_009921:4948500:4962464496246449651152652Frankia sp. EAN1pec, complete genomeapolipoprotein N-acyltransferase6e-39162
NC_015671:255808:2721732721732740081836Cellvibrio gilvus ATCC 13127 chromosome, complete genomeapolipoprotein N-acyltransferase5e-37156
NC_008278:4023918:4042963404296340448311869Frankia alni ACN14a, complete genomePutative polyprenol-phosphate-mannosyl transferase7e-36152
NC_007777:2638580:2649078264907826507211644Frankia sp. CcI3, complete genomeapolipoprotein N-acyltransferase1e-33144
NC_017955:1555990:1572027157202715735591533Modestobacter marinus, complete genomeapolipoprotein N-acyltransferase2e-1687.8
NC_017955:1611037:1616839161683916183111473Modestobacter marinus, complete genomeapolipoprotein N-acyltransferase5e-1686.7
NC_020409:560278:5643495643495658661518Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completeApolipoprotein N-acyltransferase9e-1169.3
NC_015682:1457004:1460323146032314619151593Thermodesulfobacterium sp. OPB45 chromosome, complete genomeApolipoprotein N-acyltransferase2e-1068.6
NC_016629:2971860:2989267298926729908081542Desulfovibrio africanus str. Walvis Bay chromosome, completeapolipoprotein N-acyltransferase3e-1067.8
NC_007759:1571425:1586182158618215877261545Syntrophus aciditrophicus SB, complete genomeapolipoprotein N-acyltransferase3e-1067.4
NC_014315:352395:3533513533513549161566Nitrosococcus watsoni C-113 chromosome, complete genomeapolipoprotein N-acyltransferase6e-1066.6
NC_016632:513500:5258465258465274051560Serratia symbiotica str. 'Cinara cedri' chromosome, completeapolipoprotein N-acyltransferase1e-0965.9
NC_003888:1395319:1412774141277414143481575Streptomyces coelicolor A3(2), complete genomelipoprotein N-acyltransferase (integral membrane)1e-0965.5
NC_002937:1915787:1926819192681919283271509Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completeapolipoprotein N-acyltransferase2e-0964.7
NC_007614:620500:6373776373776388791503Nitrosospira multiformis ATCC 25196 chromosome 1, completeapolipoprotein N-acyltransferase5e-0963.2
NC_010571:2041277:2062080206208020637321653Opitutus terrae PB90-1, complete genomeapolipoprotein N-acyltransferase3e-0860.8
NC_015740:2998500:3005333300533330069101578Pseudomonas stutzeri ATCC 17588 = LMG 11199 chromosome, completeapolipoprotein N-acyltransferase4e-0860.5
NC_015850:1947000:1958632195863219601521521Acidithiobacillus caldus SM-1 chromosome, complete genomeApolipoprotein N-acyltransferase / Copper homeostasis protein CutE9e-0859.3
NC_015850:548821:5558135558135573331521Acidithiobacillus caldus SM-1 chromosome, complete genomeApolipoprotein N-acyltransferase / Copper homeostasis protein CutE9e-0859.3
NC_007298:3764048:3782037378203737835001464Dechloromonas aromatica RCB, complete genomeApolipoprotein N-acyltransferase2e-0758.5
NC_015458:1938860:1942107194210719436781572Pusillimonas sp. T7-7 chromosome, complete genomeapolipoprotein N-acyltransferase2e-0758.2
NC_015850:548821:5525505525505540821533Acidithiobacillus caldus SM-1 chromosome, complete genomeApolipoprotein N-acyltransferase / Copper homeostasis protein CutE3e-0757.4
NC_016612:3087615:3100839310083931023771539Klebsiella oxytoca KCTC 1686 chromosome, complete genomeapolipoprotein N-acyltransferase3e-0757.4
NC_008789:942309:9659479659479674791533Halorhodospira halophila SL1, complete genomeapolipoprotein N-acyltransferase2e-0654.7