Pre_GI: BLASTP Hits

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Query: NC_011527:953442:975692 Coxiella burnetii CbuG_Q212, complete genome

Start: 975692, End: 976420, Length: 729

Host Lineage: Coxiella burnetii; Coxiella; Coxiellaceae; Legionellales; Proteobacteria; Bacteria

General Information: Coxiella burnetii G Q212 was isolated from a case of endocarditis and does not carry a plasmid. This organism is widely distributed in nature and can cause infections in reptiles, birds, and mammals. It causes Q fever, or 'query' fever, an atypical pneumonia first associated with abattoir workers in Australia. Transmission may be through insect vectors such as ticks that have bitten an infected wild or domesticated animal, or through an aerosol produced by domesticated animals such as sheep or cattle. The presence of a plasmid is believed to be associated with virulence and pathogenicity, however C. burnetii isolates containing plasmid QpDG are avirulent in guinea pigs and plasmidless isolates have been associated with endocarditis in humans. Coxiella burnetii has a developmental life cycle, and can grow vegetatively through binary fission, or asymmetrically and produce a spore-like cell. The spore-like cell may enable the organism to exist extracellularly for small amounts of time. This bacterium is an obligate intracellular pathogen. It is endocytosed by a host cell, a macrophage for example, and lives and replicates inside the phagolysozome, a unique property of this organism. The genome encodes proteins that have a higher than average pI, which may enable adaptation to the acidic environment of the phagolysozome. The chromosome also contains genes for a number of detoxification and stress response proteins such as dismutases that allow growth in the oxidative environment. The type IV system is similar to the one found in Legionella, which may be important for intracellular survival. This organism produces numerous ankyrin-repeat proteins that may be involved in interactions with the host cell. The genome has 83 pseudogenes, which may be a result of the typical genome-wide degradation observed with other intracellular organisms and also has a group I intron in the 23S ribosomal RNA gene.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009727:1001203:102367210236721024400729Coxiella burnetii Dugway 7E9-12, complete genomedethiobiotin synthase4e-127453
NC_011528:767940:789503789503790231729Coxiella burnetii CbuK_Q154, complete genomedethiobiotin synthetase4e-126450
NC_007484:2392739:241129524112952412026732Nitrosococcus oceani ATCC 19707, complete genomeDethiobiotin synthase3e-41168
NC_014315:1042556:104545610454561046160705Nitrosococcus watsoni C-113 chromosome, complete genomedethiobiotin synthase1e-38159
NC_012917:1740542:176002517600251760705681Pectobacterium carotovorum subsp. carotovorum PC1, complete genomedethiobiotin synthase1e-36153
NC_011601:756885:777996777996778673678Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomedithiobiotin synthetase3e-35148
NC_011353:921500:938001938001938678678Escherichia coli O157:H7 str. EC4115 chromosome, complete genomedithiobiotin synthetase2e-34146
NC_013941:1014386:103166610316661032343678Escherichia coli O55:H7 str. CB9615 chromosome, complete genomeDethiobiotin synthase2e-34146
NC_014500:2402881:240531824053182405989672Dickeya dadantii 3937 chromosome, complete genomeputative dethiobiotin synthetase1e-34146
NC_002695:917509:934636934636935313678Escherichia coli O157:H7 str. Sakai, complete genomedithiobiotin synthetase8e-34143
NC_002655:919654:936288936288936965678Escherichia coli O157:H7 EDL933, complete genomedithiobiotin synthetase8e-34143
NC_012967:786534:804896804896805573678Escherichia coli B str. REL606 chromosome, complete genomedithiobiotin synthetase9e-34143
NC_017168:3192817:320983232098323210500669Yersinia pestis A1122 chromosome, complete genomeputative dithiobiotin synthetase2e-33142
NC_013353:867869:886230886230886907678Escherichia coli O103:H2 str. 12009, complete genomedethiobiotin synthetase BioD5e-33141
AP010958:867869:886230886230886907678Escherichia coli O103:H2 str. 12009 DNA, complete genomedethiobiotin synthetase BioD5e-33141
NC_014121:2247913:227068222706822271377696Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completeputative dithiobiotin synthetase5e-32137
NC_008825:564392:565720565720566433714Methylibium petroleiphilum PM1, complete genomeDethiobiotin synthase1e-23110
NC_014307:1855356:189421318942131894902690Ralstonia solanacearum CFBP2957 chromosome, complete genomedethiobiotin synthetase1e-21103
NC_015381:4114469:411701441170144117757744Burkholderia gladioli BSR3 chromosome 1, complete sequenceDithiobiotin synthetase5e-21101
NC_020409:437781:4802414802414822532013Desulfovibrio piezophilus str. nov C1TLV30 chromosome, completehypothetical protein3e-2099
NC_002570:832480:847994847994848722729Bacillus halodurans C-125, complete genomedethiobiotin synthetase4e-2098.2
NC_009634:887205:906266906266906901636Methanococcus vannielii SB chromosome, complete genomedethiobiotin synthase5e-1684.7
NC_009635:905768:908081908081908719639Methanococcus aeolicus Nankai-3 chromosome, complete genomedethiobiotin synthase2e-1582.4
NC_015711:570910:573932573932574615684Myxococcus fulvus HW-1 chromosome, complete genomedethiobiotin synthase1e-1273.9
NC_003112:744476:764895764895765542648Neisseria meningitidis MC58, complete genomedithiobiotin synthetase2e-1272.8
NC_017505:751836:768798768798769445648Neisseria meningitidis alpha710 chromosome, complete genomeputative dethiobiotin synthetase3e-1272
NC_013016:656000:674991674991675638648Neisseria meningitidis alpha14 chromosome, complete genomedithiobiotin synthetase4e-1272
NC_017516:1535904:153974815397481540395648Neisseria meningitidis H44/76 chromosome, complete genomedethiobiotin synthase5e-1271.6
NC_017515:1527461:152795215279521528599648Neisseria meningitidis M04-240196 chromosome, complete genomedethiobiotin synthase5e-1271.2
NC_017518:828662:842410842410843057648Neisseria meningitidis NZ-05/33 chromosome, complete genomedethiobiotin synthase8e-1270.9
NC_017514:1491235:149172614917261492373648Neisseria meningitidis M01-240149 chromosome, complete genomedethiobiotin synthase8e-1270.9
NC_005072:1405884:140588414058841406546663Prochlorococcus marinus subsp. pastoris str. CCMP1986, completeputative Dethiobiotin synthase3e-1168.9
NC_015510:6653159:665888466588846659507624Haliscomenobacter hydrossis DSM 1100 chromosome, complete genomeDethiobiotin synthetase4e-1168.6
NC_014774:293800:314098314098314739642Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completedithiobiotin synthetase8e-1167.4
NC_016783:1169821:118900811890081189676669Corynebacterium diphtheriae INCA 402 chromosome, complete genomedithiobiotin synthetase1e-1067
NC_009840:1485383:148538314853831486048666Prochlorococcus marinus str. MIT 9215, complete genomeputative Dethiobiotin synthase1e-1066.6
NC_012440:585568:607037607037607714678Persephonella marina EX-H1, complete genomedethiobiotin synthase3e-1065.5
NC_014657:2283176:228317622831762283907732Caldicellulosiruptor owensensis OL chromosome, complete genomedethiobiotin synthase6e-1064.7
NC_003228:1870953:187971218797121880353642Bacteroides fragilis NCTC 9343, complete genomedithiobiotin synthetase7e-1064.3
NC_016776:1878791:188386318838631884504642Bacteroides fragilis 638R, complete genomeputative dethiobiotin synthetase9e-1063.9
NC_016932:1041306:104263610426361043325690Corynebacterium pseudotuberculosis 316 chromosome, complete genomedethiobiotin synthetase4e-0962
NC_019973:5650646:569140456914045692039636Mesorhizobium australicum WSM2073, complete genomedethiobiotin synthase5e-0961.6
NC_015675:6276357:631711563171156317750636Mesorhizobium opportunistum WSM2075 chromosome, complete genomedethiobiotin synthase5e-0961.6
NC_012985:410307:409673409673410326654Candidatus Liberibacter asiaticus str. psy62, complete genomedithiobiotin synthetase6e-0961.2
NC_011144:2674242:269836526983652699069705Phenylobacterium zucineum HLK1, complete genomedethiobiotin synthetase6e-0961.2
NC_014329:1041556:105101410510141051703690Corynebacterium pseudotuberculosis FRC41 chromosome, completedethiobiotin synthetase5e-0961.2
NC_016781:1039716:105100510510051051694690Corynebacterium pseudotuberculosis 3/99-5 chromosome, completedethiobiotin synthetase5e-0961.2
NC_017031:1039548:105083710508371051526690Corynebacterium pseudotuberculosis P54B96 chromosome, completedethiobiotin synthetase5e-0961.2
NC_017300:1045555:104848710484871049176690Corynebacterium pseudotuberculosis 1002 chromosome, completedethiobiotin synthetase5e-0961.2
NC_017301:1037519:105065010506501051339690Corynebacterium pseudotuberculosis C231 chromosome, completedethiobiotin synthetase5e-0961.2
NC_017303:1039562:105085110508511051540690Corynebacterium pseudotuberculosis I19 chromosome, complete genomedethiobiotin synthetase5e-0961.2
NC_017305:1037133:104842210484221049111690Corynebacterium pseudotuberculosis PAT10 chromosome, completedethiobiotin synthetase5e-0961.2
NC_013790:2690740:270741727074172708115699Methanobrevibacter ruminantium M1 chromosome, complete genomedethiobiotin synthetase BioD1e-0757
NC_009135:1:193919392499561Methanococcus maripaludis C5, complete genomedethiobiotin synthase2e-0755.8
NC_004461:156479:169216169216169887672Staphylococcus epidermidis ATCC 12228, complete genomedethiobiotin synthetase3e-0755.5
NC_002976:2434880:245307124530712453742672Staphylococcus epidermidis RP62A, complete genomedethiobiotin synthase3e-0755.5
NC_002678:5060670:508675850867585087393636Mesorhizobium loti MAFF303099, complete genomedithiobiotin synthetase5e-0755.1
NC_013947:460398:492868492868493527660Stackebrandtia nassauensis DSM 44728 chromosome, complete genomedethiobiotin synthase4e-0755.1
NC_009637:774358:793774793774794334561Methanococcus maripaludis C7 chromosome, complete genomedethiobiotin synthase6e-0754.7
NC_014933:2555210:255772625577262558373648Bacteroides helcogenes P 36-108 chromosome, complete genomedethiobiotin synthase7e-0754.3
NC_014834:2641514:266273426627342663372639Rhodopseudomonas palustris DX-1 chromosome, complete genomedethiobiotin synthase2e-0652.8
NC_019976:63260:666006660067283684Natronococcus occultus SP4 plasmid 2, complete sequencedethiobiotin synthase2e-0652.8
NC_009975:1034144:103531910353191035891573Methanococcus maripaludis C6, complete genomedethiobiotin synthase4e-0651.6
NC_015847:1589834:160929516092951609855561Methanococcus maripaludis XI chromosome, complete genomedethiobiotin synthase5e-0651.6