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Query: NC_011498:1345623 Helicobacter pylori P12, complete genome

Start: 1345623, End: 1371998, Length: 26376

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Helicobacter pylori P12 is a clinical isolate obtained from a patient with duodenal ulcer. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_000921:1343701*1343701136617222472Helicobacter pylori J99, complete genome015790BLASTN svgBLASTP svg
NC_008229:118000*11800014020822209Helicobacter acinonychis str. Sheeba, complete genome013770BLASTN svgBLASTP svg
NC_004917:1323783*1323783134678523003Helicobacter hepaticus ATCC 51449, complete genome2e-26129BLASTN svgBLASTP svg
NC_014802:1631483*1631483165971028228Campylobacter jejuni subsp. jejuni ICDCCJ07001 chromosome, complete3e-1591.7BLASTN svgBLASTP svg
NC_009662:222964*22296426489641933Nitratiruptor sp. SB155-2, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_009802:1886000*1886000190809922100Campylobacter concisus 13826, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_002163:1607360*1607360163467927320Campylobacter jejuni subsp. jejuni NCTC 11168, complete genome8e-1383.8BLASTN svgBLASTP svg
NC_003912:1742370*1742370177273330364Campylobacter jejuni RM1221, complete genome8e-1383.8BLASTN svgBLASTP svg
UCMB5137:28945112894511291649621986Bacillus atrophaeus UCMB-51373e-1281.8BLASTN svgBLASTP svg
NC_008787:1582110*1582110160769325584Campylobacter jejuni subsp. jejuni 81-176, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_011126:219379*21937924579226414Hydrogenobaculum sp. Y04AAS1, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_008599:29000*290005467125672Campylobacter fetus subsp. fetus 82-40, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_012039:53497*534977203018534Campylobacter lari RM2100, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_009850:1011293*1011293103921027918Arcobacter butzleri RM4018, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_009434:3611738*36117383748875137138Pseudomonas stutzeri A1501, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_015557:215397*21539725864043244Hydrogenobaculum sp. 3684 chromosome, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_015587:215433*21543325810642674Hydrogenobaculum sp. SHO chromosome, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_020411:215432*21543225810342672Hydrogenobaculum sp. HO, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_009850:757418*75741877908521668Arcobacter butzleri RM4018, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_015555:327562*32756238328255721Thermoanaerobacterium xylanolyticum LX-11 chromosome, complete8e-0763.9BLASTN svgBLASTP svg
NC_009883:383500*38350040604922550Rickettsia bellii OSU 85-389, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_007940:1138324*1138324116323224909Rickettsia bellii RML369-C, complete genome8e-0763.9BLASTN svgBLASTP svg