Query: NC_011498:1345623 Helicobacter pylori P12, complete genome
Start: 1345623, End: 1371998, Length: 26376
Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria
General Information: Helicobacter pylori P12 is a clinical isolate obtained from a patient with duodenal ulcer. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_000921:1343701* | 1343701 | 1366172 | 22472 | Helicobacter pylori J99, complete genome | 0 | 15790 | BLASTN svg | BLASTP svg |
NC_008229:118000* | 118000 | 140208 | 22209 | Helicobacter acinonychis str. Sheeba, complete genome | 0 | 13770 | BLASTN svg | BLASTP svg |
NC_004917:1323783* | 1323783 | 1346785 | 23003 | Helicobacter hepaticus ATCC 51449, complete genome | 2e-26 | 129 | BLASTN svg | BLASTP svg |
NC_014802:1631483* | 1631483 | 1659710 | 28228 | Campylobacter jejuni subsp. jejuni ICDCCJ07001 chromosome, complete | 3e-15 | 91.7 | BLASTN svg | BLASTP svg |
NC_009662:222964* | 222964 | 264896 | 41933 | Nitratiruptor sp. SB155-2, complete genome | 5e-14 | 87.7 | BLASTN svg | BLASTP svg |
NC_009802:1886000* | 1886000 | 1908099 | 22100 | Campylobacter concisus 13826, complete genome | 2e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_002163:1607360* | 1607360 | 1634679 | 27320 | Campylobacter jejuni subsp. jejuni NCTC 11168, complete genome | 8e-13 | 83.8 | BLASTN svg | BLASTP svg |
NC_003912:1742370* | 1742370 | 1772733 | 30364 | Campylobacter jejuni RM1221, complete genome | 8e-13 | 83.8 | BLASTN svg | BLASTP svg |
UCMB5137:2894511 | 2894511 | 2916496 | 21986 | Bacillus atrophaeus UCMB-5137 | 3e-12 | 81.8 | BLASTN svg | BLASTP svg |
NC_008787:1582110* | 1582110 | 1607693 | 25584 | Campylobacter jejuni subsp. jejuni 81-176, complete genome | 1e-11 | 79.8 | BLASTN svg | BLASTP svg |
NC_011126:219379* | 219379 | 245792 | 26414 | Hydrogenobaculum sp. Y04AAS1, complete genome | 2e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_008599:29000* | 29000 | 54671 | 25672 | Campylobacter fetus subsp. fetus 82-40, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_012039:53497* | 53497 | 72030 | 18534 | Campylobacter lari RM2100, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_009850:1011293* | 1011293 | 1039210 | 27918 | Arcobacter butzleri RM4018, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_009434:3611738* | 3611738 | 3748875 | 137138 | Pseudomonas stutzeri A1501, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_015557:215397* | 215397 | 258640 | 43244 | Hydrogenobaculum sp. 3684 chromosome, complete genome | 5e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_015587:215433* | 215433 | 258106 | 42674 | Hydrogenobaculum sp. SHO chromosome, complete genome | 5e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_020411:215432* | 215432 | 258103 | 42672 | Hydrogenobaculum sp. HO, complete genome | 5e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_009850:757418* | 757418 | 779085 | 21668 | Arcobacter butzleri RM4018, complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_015555:327562* | 327562 | 383282 | 55721 | Thermoanaerobacterium xylanolyticum LX-11 chromosome, complete | 8e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_009883:383500* | 383500 | 406049 | 22550 | Rickettsia bellii OSU 85-389, complete genome | 8e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_007940:1138324* | 1138324 | 1163232 | 24909 | Rickettsia bellii RML369-C, complete genome | 8e-07 | 63.9 | BLASTN svg | BLASTP svg |