Pre_GI: BLASTP Hits

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Query: NC_011250:1:5757 Borrelia duttonii Ly plasmid pl40, complete sequence

Start: 5757, End: 6848, Length: 1092

Host Lineage: Borrelia duttonii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia duttonii Ly was isolated from a 2-year-old girl with tick-borne relapsing fever in Tanzania. Borrelia duttonii is the causative agent of tick-borne relapsing fever in east Africa. This disease is endemic in much of east Africa and is one of the top 10 diseases associated with deaths in children under the age of five. This disease is transmitted by the bite of the soft-bodied tick Ornithodoros moubata. Ticks become infected with Borrelia duttonii while feeding on an infected rodent. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Humans become exposed to the infected ticks through contact with rodents or rodent nests. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011248:23500:1034610346114301085Borrelia duttonii Ly plasmid pl35, complete sequence3e-129461
NC_011250:1:2769276938991131Borrelia duttonii Ly plasmid pl40, complete sequencevlp protein, alpha subfamily4e-75281
NC_011264:11018:3562356246501089Borrelia duttonii Ly plasmid pl32, complete sequencevlp protein, alpha subfamily2e-68259
NC_011229:1:7068706881651098Borrelia duttonii Ly, complete genomevlp protein, alpha subfamily5e-67254
NC_011244:1:2174217432951122Borrelia recurrentis A1, complete genomevlp protein, alpha subfamily9e-56217
NC_011256:37617:533305333053888559Borrelia duttonii Ly plasmid pl70, complete sequence3e-28126
NC_011251:25946:87528752100021251Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein1e-24114
NC_011251:1:87528752100021251Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein1e-24114
NC_011244:1:11420420Borrelia recurrentis A1, complete genome2e-20100
NC_011248:23500:111741117411431258Borrelia duttonii Ly plasmid pl35, complete sequence9e-1684.7
NC_011248:23500:253825382792255Borrelia duttonii Ly plasmid pl35, complete sequence4e-1169.3
NC_011248:23500:4050405052041155Borrelia duttonii Ly plasmid pl35, complete sequencevlp protein, beta subfamily3e-0963.2
NC_011256:37617:4696546965479871023Borrelia duttonii Ly plasmid pl70, complete sequencevlp protein, gamma subfamily2e-0860.5
NC_011244:1:6895689579891095Borrelia recurrentis A1, complete genomevlp protein, delta subfamily1e-0758.2
NC_011264:11018:249692496925887919Borrelia duttonii Ly plasmid pl32, complete sequence3e-0756.6
NC_011256:37617:4338143381444541074Borrelia duttonii Ly plasmid pl70, complete sequencevlp protein, beta subfamily2e-0653.9
NC_011256:37617:5954159541606201080Borrelia duttonii Ly plasmid pl70, complete sequencevlp protein, beta subfamily4e-0652.8
NC_011251:1:2399239934301032Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily5e-0652.4
NC_011251:25946:2399239934301032Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily5e-0652.4
NC_011262:13649:16516512141050Borrelia duttonii Ly plasmid pl31, complete sequencevlp protein, delta subfamily7e-0652
NC_011250:1:706370637850788Borrelia duttonii Ly plasmid pl40, complete sequence8e-0652