Pre_GI: BLASTP Hits

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Query: NC_011250:1:2769 Borrelia duttonii Ly plasmid pl40, complete sequence

Start: 2769, End: 3899, Length: 1131

Host Lineage: Borrelia duttonii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia duttonii Ly was isolated from a 2-year-old girl with tick-borne relapsing fever in Tanzania. Borrelia duttonii is the causative agent of tick-borne relapsing fever in east Africa. This disease is endemic in much of east Africa and is one of the top 10 diseases associated with deaths in children under the age of five. This disease is transmitted by the bite of the soft-bodied tick Ornithodoros moubata. Ticks become infected with Borrelia duttonii while feeding on an infected rodent. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Humans become exposed to the infected ticks through contact with rodents or rodent nests. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011264:11018:3562356246501089Borrelia duttonii Ly plasmid pl32, complete sequencevlp protein, alpha subfamily9e-67254
NC_011229:1:7068706881651098Borrelia duttonii Ly, complete genomevlp protein, alpha subfamily1e-66253
NC_011250:1:5757575768481092Borrelia duttonii Ly plasmid pl40, complete sequencevlp protein, alpha subfamily3e-61236
NC_011244:1:2174217432951122Borrelia recurrentis A1, complete genomevlp protein, alpha subfamily3e-58226
NC_011248:23500:1034610346114301085Borrelia duttonii Ly plasmid pl35, complete sequence1e-41170
NC_011256:37617:533305333053888559Borrelia duttonii Ly plasmid pl70, complete sequence1e-25117
NC_011251:1:87528752100021251Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein1e-21104
NC_011251:25946:87528752100021251Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein1e-21104
NC_011256:37617:5698856988580191032Borrelia duttonii Ly plasmid pl70, complete sequencevlp protein, delta subfamily1e-1584.7
NC_011244:1:11420420Borrelia recurrentis A1, complete genome2e-1480.5
NC_011251:1:4918491859611044Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily2e-1273.6
NC_011251:25946:4918491859611044Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily2e-1273.6
NC_011262:13649:16516512141050Borrelia duttonii Ly plasmid pl31, complete sequencevlp protein, delta subfamily3e-1273.2
NC_011248:23500:253825382792255Borrelia duttonii Ly plasmid pl35, complete sequence2e-1170.5
NC_011251:1:2399239934301032Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily1e-1067.8
NC_011251:25946:2399239934301032Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily1e-1067.8
NC_011248:23500:5397539764251029Borrelia duttonii Ly plasmid pl35, complete sequencevlp protein, delta subfamily8e-1065.1
NC_011264:11018:249692496925887919Borrelia duttonii Ly plasmid pl32, complete sequence2e-0757.4
NC_011248:23500:111741117411431258Borrelia duttonii Ly plasmid pl35, complete sequence5e-0755.8
NC_011229:1:3342334244211080Borrelia duttonii Ly, complete genomevlp protein, gamma subfamily5e-0755.8
NC_011256:37617:4338143381444541074Borrelia duttonii Ly plasmid pl70, complete sequencevlp protein, beta subfamily7e-0755.5
NC_011251:1:365036504642993Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily1e-0654.3
NC_011251:25946:365036504642993Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily1e-0654.3
NC_011264:11018:483748375811975Borrelia duttonii Ly plasmid pl32, complete sequencevlp protein, delta subfamily4e-0652.8
NC_011248:23500:2352823528246041077Borrelia duttonii Ly plasmid pl35, complete sequencevlp protein, delta subfamily4e-0652.8
NC_011248:23500:90319031100561026Borrelia duttonii Ly plasmid pl35, complete sequencevlp protein, delta subfamily6e-0652.4