Pre_GI: BLASTP Hits

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Query: NC_011250:1:250 Borrelia duttonii Ly plasmid pl40, complete sequence

Start: 250, End: 1101, Length: 852

Host Lineage: Borrelia duttonii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia duttonii Ly was isolated from a 2-year-old girl with tick-borne relapsing fever in Tanzania. Borrelia duttonii is the causative agent of tick-borne relapsing fever in east Africa. This disease is endemic in much of east Africa and is one of the top 10 diseases associated with deaths in children under the age of five. This disease is transmitted by the bite of the soft-bodied tick Ornithodoros moubata. Ticks become infected with Borrelia duttonii while feeding on an infected rodent. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Humans become exposed to the infected ticks through contact with rodents or rodent nests. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011251:25946:396903969040541852Borrelia duttonii Ly plasmid pl41, complete sequenceantigen P35-like protein1e-124445
NC_011264:11018:3434888855Borrelia duttonii Ly plasmid pl32, complete sequenceantigen P35-like protein2e-124445
NC_011248:23500:122412242078855Borrelia duttonii Ly plasmid pl35, complete sequenceantigen P35-like protein3e-122437
NC_011229:1:5245241378855Borrelia duttonii Ly, complete genomeantigen P35-like protein7e-119426
NC_011251:25946:11808808Borrelia duttonii Ly plasmid pl41, complete sequenceantigen P35-like protein5e-107387
NC_011251:1:11808808Borrelia duttonii Ly plasmid pl41, complete sequenceantigen P35-like protein5e-107387
NC_008564:40946:497074970750426720Borrelia afzelii PKo plasmid lp60, complete sequencehypothetical protein1e-1377
NC_001857:31716:436214362144469849Borrelia burgdorferi B31 plasmid lp54, complete sequencehypothetical protein6e-1168.2
NC_001857:31716:425604256043483924Borrelia burgdorferi B31 plasmid lp54, complete sequenceantigen, P353e-0962.4
NC_015919:36890:431634316344035873Borrelia bissettii DN127 plasmid lp54, complete sequencehypothetical protein5e-0962
NC_015919:36890:458894588946554666Borrelia bissettii DN127 plasmid lp54, complete sequencehypothetical protein5e-0962
NC_015919:36890:420304203042995966Borrelia bissettii DN127 plasmid lp54, complete sequencehypothetical protein4e-0962
NC_008564:40946:453714537146345975Borrelia afzelii PKo plasmid lp60, complete sequenceantigen, P357e-0961.6
NC_006129:38600:441304413044960831Borrelia garinii PBi plasmid lp54, complete sequencehypothetical protein1e-0860.5
NC_008564:40946:465114651147362852Borrelia afzelii PKo plasmid lp60, complete sequencehypothetical protein9e-0857.8
NC_001857:31716:502225022251112891Borrelia burgdorferi B31 plasmid lp54, complete sequenceantigen, P35, putative1e-0757
NC_015919:36890:518695186952747879Borrelia bissettii DN127 plasmid lp54, complete sequencehypothetical protein2e-0756.6
NC_006129:38600:430074300743963957Borrelia garinii PBi plasmid lp54, complete sequenceantigen, P353e-0652.8