Pre_GI: BLASTP Hits

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Query: NC_011248:23500:30740 Borrelia duttonii Ly plasmid pl35, complete sequence

Start: 30740, End: 31347, Length: 608

Host Lineage: Borrelia duttonii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia duttonii Ly was isolated from a 2-year-old girl with tick-borne relapsing fever in Tanzania. Borrelia duttonii is the causative agent of tick-borne relapsing fever in east Africa. This disease is endemic in much of east Africa and is one of the top 10 diseases associated with deaths in children under the age of five. This disease is transmitted by the bite of the soft-bodied tick Ornithodoros moubata. Ticks become infected with Borrelia duttonii while feeding on an infected rodent. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Humans become exposed to the infected ticks through contact with rodents or rodent nests. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011262:13649:207592075921397639Borrelia duttonii Ly plasmid pl31, complete sequencebdr protein2e-25115
NC_011251:25946:308273082731387561Borrelia duttonii Ly plasmid pl41, complete sequencebdr protein7e-24110
NC_011262:13649:280212802128581561Borrelia duttonii Ly plasmid pl31, complete sequencebdr protein7e-24110
NC_011248:23500:345003450035099600Borrelia duttonii Ly plasmid pl35, complete sequencebdr protein4e-1271.2
NC_014974:246404:248250248250249098849Thermus scotoductus SA-01 chromosome, complete genomerepeat motif-containing protein3e-1168.2
NC_011251:25946:102601026010742483Borrelia duttonii Ly plasmid pl41, complete sequencebdr protein2e-1065.5
NC_011251:1:102601026010742483Borrelia duttonii Ly plasmid pl41, complete sequencebdr protein2e-1065.5
NC_011264:11018:225362253623089554Borrelia duttonii Ly plasmid pl32, complete sequence2e-0859.3
NC_015906:49557:581495814958796648Borrelia bissettii DN127 plasmid cp32-quad, complete sequenceKID repeat family protein2e-0652.4