Pre_GI: BLASTP Hits

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Query: NC_011248:23500:29213 Borrelia duttonii Ly plasmid pl35, complete sequence

Start: 29213, End: 29773, Length: 561

Host Lineage: Borrelia duttonii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia duttonii Ly was isolated from a 2-year-old girl with tick-borne relapsing fever in Tanzania. Borrelia duttonii is the causative agent of tick-borne relapsing fever in east Africa. This disease is endemic in much of east Africa and is one of the top 10 diseases associated with deaths in children under the age of five. This disease is transmitted by the bite of the soft-bodied tick Ornithodoros moubata. Ticks become infected with Borrelia duttonii while feeding on an infected rodent. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Humans become exposed to the infected ticks through contact with rodents or rodent nests. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011256:37617:376173761738177561Borrelia duttonii Ly plasmid pl70, complete sequenceplasmid partitioning associated protein-11e-49195
NC_001854:1:119241192412478555Borrelia burgdorferi B31 plasmid lp28-4, complete sequencehypothetical protein9e-35146
NC_000956:1:239762397624542567Borrelia burgdorferi B31 plasmid lp56, complete sequencehypothetical protein7e-32136
NC_011247:110545:129640129640130203564Borrelia duttonii Ly plasmid pl165, complete sequenceplasmid partitioning associated protein-11e-31135
NC_015906:49557:860086009166567Borrelia bissettii DN127 plasmid cp32-quad, complete sequencehypothetical protein2e-31135
NC_015906:1:860086009166567Borrelia bissettii DN127 plasmid cp32-quad, complete sequencehypothetical protein2e-31135
NC_011264:11018:210532105321655603Borrelia duttonii Ly plasmid pl32, complete sequenceplasmid partitioning associated protein-12e-31134
NC_015919:1:130601306013644585Borrelia bissettii DN127 plasmid lp54, complete sequencepartition protein2e-30132
NC_008564:1:154471544716031585Borrelia afzelii PKo plasmid lp60, complete sequencehypothetical protein2e-30131
NC_015906:49557:562335623356796564Borrelia bissettii DN127 plasmid cp32-quad, complete sequencehypothetical protein7e-30130
NC_006129:1:131721317213795624Borrelia garinii PBi plasmid lp54, complete sequencehypothetical protein7e-30129
NC_000956:1:580358036339537Borrelia burgdorferi B31 plasmid lp56, complete sequencehypothetical protein2e-1065.5
NC_015906:1:364393643936609171Borrelia bissettii DN127 plasmid cp32-quad, complete sequencehypothetical protein2e-0858.9