Pre_GI: BLASTP Hits

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Query: NC_011248:23500:27851 Borrelia duttonii Ly plasmid pl35, complete sequence

Start: 27851, End: 28468, Length: 618

Host Lineage: Borrelia duttonii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia duttonii Ly was isolated from a 2-year-old girl with tick-borne relapsing fever in Tanzania. Borrelia duttonii is the causative agent of tick-borne relapsing fever in east Africa. This disease is endemic in much of east Africa and is one of the top 10 diseases associated with deaths in children under the age of five. This disease is transmitted by the bite of the soft-bodied tick Ornithodoros moubata. Ticks become infected with Borrelia duttonii while feeding on an infected rodent. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Humans become exposed to the infected ticks through contact with rodents or rodent nests. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006129:1:145241452415096573Borrelia garinii PBi plasmid lp54, complete sequencehypothetical protein2e-32139
NC_008564:1:167891678917334546Borrelia afzelii PKo plasmid lp60, complete sequencehypothetical protein2e-32138
NC_011247:110545:128307128307128858552Borrelia duttonii Ly plasmid pl165, complete sequencePF49 plasmid partition protein7e-32136
NC_011256:37617:389383893839471534Borrelia duttonii Ly plasmid pl70, complete sequencePF49 plasmid partition protein4e-30131
NC_001854:1:132651326513837573Borrelia burgdorferi B31 plasmid lp28-4, complete sequenceconserved hypothetical protein,1e-27122
NC_011264:11018:197031970320302600Borrelia duttonii Ly plasmid pl32, complete sequencePF49 plasmid partition protein1e-27122
NC_015906:49557:575725757258132561Borrelia bissettii DN127 plasmid cp32-quad, complete sequenceplasmid partition family protein1e-26119
NC_015906:1:226572265723103447Borrelia bissettii DN127 plasmid cp32-quad, complete sequenceplasmid partition family protein7e-26117
NC_015906:1:9939993910496558Borrelia bissettii DN127 plasmid cp32-quad, complete sequenceplasmid partition family protein4e-25114
NC_015906:1:348623486235422561Borrelia bissettii DN127 plasmid cp32-quad, complete sequenceplasmid partition family protein5e-1477.4
NC_000956:1:424942494986738Borrelia burgdorferi B31 plasmid lp56, complete sequencehypothetical protein9e-1063.5