Pre_GI: BLASTP Hits

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Query: NC_011248:23500:11645 Borrelia duttonii Ly plasmid pl35, complete sequence

Start: 11645, End: 12193, Length: 549

Host Lineage: Borrelia duttonii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia duttonii Ly was isolated from a 2-year-old girl with tick-borne relapsing fever in Tanzania. Borrelia duttonii is the causative agent of tick-borne relapsing fever in east Africa. This disease is endemic in much of east Africa and is one of the top 10 diseases associated with deaths in children under the age of five. This disease is transmitted by the bite of the soft-bodied tick Ornithodoros moubata. Ticks become infected with Borrelia duttonii while feeding on an infected rodent. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Humans become exposed to the infected ticks through contact with rodents or rodent nests. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011250:1:706370637850788Borrelia duttonii Ly plasmid pl40, complete sequence1e-55215
NC_011264:11018:1313613136141581023Borrelia duttonii Ly plasmid pl32, complete sequencevlp protein, delta subfamily8e-35146
NC_011251:1:4918491859611044Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily6e-34143
NC_011251:25946:4918491859611044Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily6e-34143
NC_011251:25946:365036504642993Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily2e-30132
NC_011251:1:365036504642993Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily2e-30132
NC_011248:23500:247942479425744951Borrelia duttonii Ly plasmid pl35, complete sequencevlp protein, delta subfamily9e-30129
NC_011264:11018:110181101812000983Borrelia duttonii Ly plasmid pl32, complete sequence6e-28123
NC_011262:13649:16516512141050Borrelia duttonii Ly plasmid pl31, complete sequencevlp protein, delta subfamily2e-26118
NC_011248:23500:90319031100561026Borrelia duttonii Ly plasmid pl35, complete sequencevlp protein, delta subfamily2e-26118
NC_011251:25946:2399239934301032Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily6e-23107
NC_011251:1:2399239934301032Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily6e-23107
NC_011248:23500:5397539764251029Borrelia duttonii Ly plasmid pl35, complete sequencevlp protein, delta subfamily4e-22104
NC_011264:11018:483748375811975Borrelia duttonii Ly plasmid pl32, complete sequencevlp protein, delta subfamily1e-21102
NC_011251:25946:357883578836756969Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein, delta subfamily2e-1788.6
NC_011256:37617:421914219143180990Borrelia duttonii Ly plasmid pl70, complete sequencevlp protein, delta subfamily2e-1788.2
NC_011256:37617:5698856988580191032Borrelia duttonii Ly plasmid pl70, complete sequencevlp protein, delta subfamily4e-1477.4
NC_011248:23500:2352823528246041077Borrelia duttonii Ly plasmid pl35, complete sequencevlp protein, delta subfamily6e-1477
NC_011251:25946:619961997130932Borrelia duttonii Ly plasmid pl41, complete sequence4e-1270.9
NC_011251:1:619961997130932Borrelia duttonii Ly plasmid pl41, complete sequence4e-1270.9
NC_011251:25946:376193761938596978Borrelia duttonii Ly plasmid pl41, complete sequencevlp protein1e-0653.1