Pre_GI: BLASTP Hits

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Query: NC_011244:94756:112474 Borrelia recurrentis A1, complete genome

Start: 112474, End: 113064, Length: 591

Host Lineage: Borrelia recurrentis; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia recurrentis isolated from adult patient with louse-borne relapsing fever in Ethiopia. Borrelia recurrentis is the causative agent of louse-borne relapsing fever. Prior to World War II, this organism was responsible for large disease outbreaks with a mortality of up to 40% in much of the world. Currently this disease is limited to parts of Africa, China, and Peru. B. recurrentis is transmitted when infected human body lice (Pediculus humanus) are crushed and their fluids contaminate mucous membranes or breaks in the skin. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010673:82586:100358100358100954597Borrelia hermsii DAH, complete genomephosphoribosyltransferase1e-100365
NC_008710:79100:100282100282100872591Borrelia turicatae 91E135, complete genomephosphoribosyltransferase5e-101366
NC_008228:2068641:206864120686412069198558Pseudoalteromonas atlantica T6c, complete genomeputative hypoxanthine phosphoribosyltransferase1e-1686.7
NC_002967:1589069:158847015884701589072603Treponema denticola ATCC 35405, complete genomephosphoribosyl transferase domain protein1e-42172