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Query: NC_011080:4177443:4193191 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Start: 4193191, End: 4194069, Length: 879

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014618:1295322:130315513031551304033879Enterobacter cloacae SCF1 chromosome, complete genomedeoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase5e-102370
NC_020207:843822:862126862126863100975Enterococcus faecium NRRL B-2354, complete genometagatose-1, 6-diphosphate aldolase5e-1478.6
NC_015675:1721543:174590217459021746810909Mesorhizobium opportunistum WSM2075 chromosome, complete genomedeoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase3e-1272.8
NC_011831:4043802:4059682405968240607221041Chloroflexus aggregans DSM 9485, complete genomeTagatose-bisphosphate aldolase4e-0962