Pre_GI: BLASTP Hits

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Query: NC_011080:1944226:1950380 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Start: 1950380, End: 1951102, Length: 723

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016863:1905454:191160819116081912330723Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1type III-secreted effector protein2e-140498
NC_011083:1993672:199982019998202000542723Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,guanine nucleotide exchange factor SopE2e-140498
NC_003197:1945858:195201219520121952734723Salmonella typhimurium LT2, complete genometype III-secreted effector protein2e-140498
NC_011205:1391971:141497014149701415692723Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853guanine nucleotide exchange factor SopE2e-140498
NC_016810:1903426:190958019095801910302723Salmonella enterica subsp. enterica serovar Typhimurium strinvasion-associated secreted effector protein (sopE2)2e-140498
NC_016831:1690811:169696016969601697682723Salmonella enterica subsp. enterica serovar Gallinarum/pulloruminvasion-associated secreted effector protein (sopE2)2e-140498
NC_016856:1957263:196341719634171964139723Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Stype III-secreted effector protein2e-140498
NC_016857:1903426:190958019095801910302723Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74type III-secreted effector protein2e-140498
NC_016860:1943203:194935719493571950079723Salmonella enterica subsp. enterica serovar Typhimurium strguanine nucleotide exchange factor SopE2e-140498
NC_006905:1961774:196796219679621968684723Salmonella enterica subsp. enterica serovar Choleraesuis strTypeIII-secreted protein effector: invasion-associated protein3e-138491
NC_011094:1923870:193002419300241930746723Salmonella enterica subsp. enterica serovar Schwarzengrund strguanine nucleotide exchange factor SopE3e-137487
NC_011147:1057259:108341610834161084138723Salmonella enterica subsp. enterica serovar Paratyphi A strtype III-secreted protein effector: invasion-associated protein1e-136485
NC_003198:4453457:448180144818014482523723Salmonella enterica subsp. enterica serovar Typhi str. CT18,invasion-associated secreted protein.4e-95347
NC_011205:1391971:139623113962311396953723Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853guanine nucleotide exchange factor SopE4e-90330
NC_011294:1220526:124313612431361243858723Salmonella enterica subsp. enterica serovar Enteritidis strtype III secretion system, secreted effector protein SopE5e-90330
NC_011274:1299475:130731213073121308034723Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91type III secretion system, effector protein SopE3e-89327
NC_017046:1902788:190894219089421909406465Salmonella enterica subsp. enterica serovar Typhimurium str. 798invasion-associated secreted effector protein (sopE2)3e-87321
NC_011149:1236689:124815612481561248620465Salmonella enterica subsp. enterica serovar Agona str. SL483,guanine nucleotide exchange factor SopE7e-86316
NC_016832:1090274:110603011060301106494465Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Guanine nucleotide exchange factor sopE2e-84312
NC_006349:1630514:165236116523611653146786Burkholderia mallei ATCC 23344 chromosome 2, complete sequencetype III secretion target BopE9e-1167.4
NC_003198:1867456:187361018736101874331722Salmonella enterica subsp. enterica serovar Typhi str. CT18,1e-0756.6