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Query: NC_010729:1818500:1826408 Porphyromonas gingivalis ATCC 33277, complete genome

Start: 1826408, End: 1827403, Length: 996

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015571:1495286:150282515028251503790966Porphyromonas gingivalis TDC60, complete genomehypothetical protein0672
NC_013730:4399643:440275044027504403340591Spirosoma linguale DSM 74, complete genomehypothetical protein6e-1685.1
NC_015703:1087809:109846510984651099421957Runella slithyformis DSM 19594 chromosome, complete genomehypothetical protein4e-1479
NC_014836:2581939:260121426012142601774561Desulfurispirillum indicum S5 chromosome, complete genomehypothetical protein2e-1376.6
NC_014924:1701952:1711297171129717124451149Pseudoxanthomonas suwonensis 11-1 chromosome, complete genomehypothetical protein1e-1170.9
NC_019904:334654:345113345113345778666Echinicola vietnamensis DSM 17526 chromosome, complete genomehypothetical protein2e-1170.1
NC_018679:2541986:254198625419862542564579Alteromonas macleodii str. 'Balearic Sea AD45' chromosome, completehypothetical protein1e-0963.9
NC_015711:7191968:720211972021197202610492Myxococcus fulvus HW-1 chromosome, complete genomehypothetical protein2e-0963.5
NC_013730:933089:933089933089933745657Spirosoma linguale DSM 74, complete genomehypothetical protein6e-0962