Pre_GI: BLASTN Hits

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Query: NC_010723:371741 Clostridium botulinum E3 str. Alaska E43, complete genome

Start: 371741, End: 393522, Length: 21782

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was probably isolated from salmon eggs associated with a foodborne case of botulism in Alaska, however the exact details are not available. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_009850:1862602*1862602190488342282Arcobacter butzleri RM4018, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_009850:41309341309343688323791Arcobacter butzleri RM4018, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_009850:1011293*1011293103921027918Arcobacter butzleri RM4018, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_007530:5033095*5033095507221139117Bacillus anthracis str. 'Ames Ancestor', complete genome1e-0869.9BLASTN svgBLASTP svg
NC_003997:5032969*5032969507209939131Bacillus anthracis str. Ames, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_005945:5053000*5053000507465121652Bacillus anthracis str. Sterne, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_003909:4996783*4996783505271855936Bacillus cereus ATCC 10987, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_006274:5122500*5122500514359021091Bacillus cereus E33L, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_012225:21989872198987222132922343Brachyspira hyodysenteriae WA1, complete genome4e-36161BLASTN svgBLASTP svg
NC_012225:25232622523262254758024319Brachyspira hyodysenteriae WA1, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014330:1113145*1113145114959936455Brachyspira pilosicoli 95/1000 chromosome, complete genome2e-31145BLASTN svgBLASTP svg
NC_018607:290500*29050033195841459Brachyspira pilosicoli B2904 chromosome, complete genome2e-31145BLASTN svgBLASTP svg
NC_019908:2068631*2068631210767339043Brachyspira pilosicoli P43/6/78 chromosome, complete genome2e-31145BLASTN svgBLASTP svg
NC_018604:2579000*2579000263363754638Brachyspira pilosicoli WesB complete genome2e-31145BLASTN svgBLASTP svg
NC_004545:15650*156506959953950Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genome5e-1797.6BLASTN svgBLASTP svg
NC_014652:666227*66622768697120745Caldicellulosiruptor hydrothermalis 108 chromosome, complete7e-1383.8BLASTN svgBLASTP svg
NC_015949:2002752*2002752202359920848Caldicellulosiruptor lactoaceticus 6A chromosome, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_012563:37298173729817376659036774Clostridium botulinum A2 str. Kyoto, complete genome0680BLASTN svgBLASTP svg
NC_012563:24660002466000248852922530Clostridium botulinum A2 str. Kyoto, complete genome7e-1693.7BLASTN svgBLASTP svg
NC_010520:35800003580000360470824709Clostridium botulinum A3 str. Loch Maree, complete genome1e-153551BLASTN svgBLASTP svg
NC_010674:37062937062939810727479Clostridium botulinum B str. Eklund 17B, complete genome07360BLASTN svgBLASTP svg
NC_010674:13904731390473141116620694Clostridium botulinum B str. Eklund 17B, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_010516:35450173545017356809923083Clostridium botulinum B1 str. Okra, complete genome2e-50208BLASTN svgBLASTP svg
NC_010516:23740002374000239681422815Clostridium botulinum B1 str. Okra, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_010516:34660003466000348809922100Clostridium botulinum B1 str. Okra, complete genome6e-38167BLASTN svgBLASTP svg
NC_010516:583870*58387060159917730Clostridium botulinum B1 str. Okra, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_010723:13792561379256140062221367Clostridium botulinum E3 str. Alaska E43, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_011898:426951*42695146616239212Clostridium cellulolyticum H10, complete genome3e-24121BLASTN svgBLASTP svg
NC_014393:36509573650957366964218686Clostridium cellulovorans 743B chromosome, complete genome2e-161577BLASTN svgBLASTP svg
NC_009089:96595996595998833722379Clostridium difficile 630, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_009089:370555*37055539409923545Clostridium difficile 630, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_013316:89178289178291434722566Clostridium difficile R20291, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_015275:3594890*3594890363588740998Clostridium lentocellum DSM 5427 chromosome, complete genome6e-35157BLASTN svgBLASTP svg
NC_008593:21367592136759215512718369Clostridium novyi NT, complete genome1e-140507BLASTN svgBLASTP svg
NC_008593:15131071513107153682423718Clostridium novyi NT, complete genome9e-31143BLASTN svgBLASTP svg
NC_008593:22818962281896230590024005Clostridium novyi NT, complete genome3e-98367BLASTN svgBLASTP svg
NC_021182:14735351473535149659923065Clostridium pasteurianum BC1, complete genome7e-121442BLASTN svgBLASTP svg
NC_008262:24980002498000252144223443Clostridium perfringens SM101, complete genome01287BLASTN svgBLASTP svg
NC_003366:12878312878314709918317Clostridium perfringens str. 13, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_020291:49100049100051106420065Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome02391BLASTN svgBLASTP svg
NC_020291:22914182291418231430022883Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome01675BLASTN svgBLASTP svg
NC_020134:2832857*2832857285642223566Clostridium stercorarium subsp. stercorarium DSM 8532, complete5e-20107BLASTN svgBLASTP svg
NC_014614:65600065600067926623267Clostridium sticklandii, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_004557:2078000*2078000210049622497Clostridium tetani E88, complete genome1e-20109BLASTN svgBLASTP svg
NC_004557:25524182552418257431921902Clostridium tetani E88, complete genome0678BLASTN svgBLASTP svg
NC_011830:15044971504497153619331697Desulfitobacterium hafniense DCB-2, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_003454:86536886536888609920732Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete1e-1489.7BLASTN svgBLASTP svg
NC_014654:391201*39120141082919629Halanaerobium sp. 'sapolanicus' chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_019978:31534631534633383318488Halobacteroides halobius DSM 5150, complete genome3e-18101BLASTN svgBLASTP svg
NC_019978:39000*390005838419385Halobacteroides halobius DSM 5150, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_014002:403180*40318042237819199Methanohalophilus mahii DSM 5219 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_010718:46440546440548434419940Natranaerobius thermophilus JW/NM-WN-LF, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_010718:1959517*1959517198298623470Natranaerobius thermophilus JW/NM-WN-LF, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_008767:2160000*2160000218237122372Neisseria meningitidis FAM18, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_013406:59544725954472597839723926Paenibacillus sp. Y412MC10 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_010003:449192*44919247891429723Petrotoga mobilis SJ95, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_002976:15407941540794156113820345Staphylococcus epidermidis RP62A, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_020164:88751088751091047422965Staphylococcus warneri SG1, complete genome2e-22115BLASTN svgBLASTP svg
NC_014914:13272451327245135092223678Taylorella equigenitalis MCE9 chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_014538:15981061598106162581827713Thermoanaerobacter sp. X513 chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_015958:677500*67750069545217953Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genome1e-26129BLASTN svgBLASTP svg
NC_014410:80050080050084758147082Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,3e-0661.9BLASTN svgBLASTP svg