Pre_GI: BLASTP Hits

Some Help

Query: NC_010723:2735196:2752387 Clostridium botulinum E3 str. Alaska E43, complete genome

Start: 2752387, End: 2753886, Length: 1500

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was probably isolated from salmon eggs associated with a foodborne case of botulism in Alaska, however the exact details are not available. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010674:2930259:2948077294807729495761500Clostridium botulinum B str. Eklund 17B, complete genomestage V sporulation protein B0949
NC_008262:1795914:1810394181039418119231530Clostridium perfringens SM101, complete genomestage V sporulation protein B8e-160563
NC_003366:1901898:1921032192103219225611530Clostridium perfringens str. 13, complete genomestage V sporulation protein B2e-159562
NC_008261:2117207:2136345213634521378741530Clostridium perfringens ATCC 13124, complete genomestage V sporulation protein B2e-159562
NC_011899:2286884:2305150230515023067691620Halothermothrix orenii H 168, complete genomepolysaccharide biosynthesis protein6e-38159
NC_014614:554949:5606185606185622041587Clostridium sticklandii, complete genomePolysaccharide biosynthesis protein8e-37155
NC_014654:2180994:2196958219695821985831626Halanaerobium sp. 'sapolanicus' chromosome, complete genomestage V sporulation protein B2e-35150
NC_011725:4373721:4393036439303643945951560Bacillus cereus B4264 chromosome, complete genomestage V sporulation protein B2e-35150
NC_004722:4333643:4349802434980243513611560Bacillus cereus ATCC 14579, complete genomeStage V sporulation protein B2e-35150
NC_009922:2850320:2862936286293628645341599Alkaliphilus oremlandii OhILAs, complete genomepolysaccharide biosynthesis protein7e-35149
NC_009633:168266:1814621814621830601599Alkaliphilus metalliredigens QYMF chromosome, complete genomepolysaccharide biosynthesis protein5e-34145
NC_010718:2460893:2473528247352824751321605Natranaerobius thermophilus JW/NM-WN-LF, complete genomepolysaccharide biosynthesis protein5e-32139
NC_014152:191200:1918671918671934291563Thermincola sp. JR, complete genomepolysaccharide biosynthesis protein7e-28125
NC_019978:91483:1091351091351107391605Halobacteroides halobius DSM 5150, complete genomemembrane protein involved in the export of O-antigen and teichoic acid1e-27124
NC_014652:1898969:1899836189983619013231488Caldicellulosiruptor hydrothermalis 108 chromosome, completepolysaccharide biosynthesis protein1e-25117
NC_014721:1953708:1953708195370819551951488Caldicellulosiruptor kristjanssonii 177R1B chromosome, completepolysaccharide biosynthesis protein8e-25115
NC_012034:893000:9112299112299127161488Anaerocellum thermophilum DSM 6725, complete genomepolysaccharide biosynthesis protein7e-25115
NC_015690:1818333:1903736190373619052741539Paenibacillus mucilaginosus KNP414 chromosome, complete genomestage V sporulation protein B6e-25115
NC_016935:2347691:2434934243493424364721539Paenibacillus mucilaginosus 3016 chromosome, complete genomestage V sporulation protein B6e-25115
NC_014657:742739:7629837629837644761494Caldicellulosiruptor owensensis OL chromosome, complete genomepolysaccharide biosynthesis protein6e-25115
NC_014392:848195:8684388684388699311494Caldicellulosiruptor obsidiansis OB47 chromosome, complete genomepolysaccharide biosynthesis protein5e-25115
NC_010718:1:1621516215177951581Natranaerobius thermophilus JW/NM-WN-LF, complete genomepolysaccharide biosynthesis protein1e-24114
NC_015949:1363053:1363053136305313645401488Caldicellulosiruptor lactoaceticus 6A chromosome, complete genomepolysaccharide biosynthesis protein2e-24114
NC_009697:3753527:3754987375498737565221536Clostridium botulinum A str. ATCC 19397 chromosome, completestage V sporulation protein B3e-22107
NC_009698:3647955:3652097365209736536321536Clostridium botulinum A str. Hall chromosome, complete genomestage V sporulation protein B3e-22107
NC_017297:3878540:3880000388000038815351536Clostridium botulinum F str. 230613 chromosome, complete genomestage V sporulation protein B3e-22107
NC_010516:3845942:3850005385000538515401536Clostridium botulinum B1 str. Okra, complete genomestage V sporulation protein B1e-22107
NC_014483:39729:4764247642493001659Paenibacillus polymyxa E681 chromosome, complete genomeMembrane protein involved in the export of O-antigen and teichoic acid3e-21103
NC_008262:2649289:2703144270314427046761533Clostridium perfringens SM101, complete genomestage V sporulation protein B1e-20101
NC_020291:117983:1236071236071251421536Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomestage V sporulation protein B6e-1995.9
NC_009012:3591687:3604489360448936060961608Clostridium thermocellum ATCC 27405, complete genomepolysaccharide biosynthesis protein2e-1687.4
NC_006177:2883476:2883476288347628850471572Symbiobacterium thermophilum IAM 14863, complete genomestage V sporulation protein B9e-1582
NC_016627:4490435:4510663451066345122581596Clostridium clariflavum DSM 19732 chromosome, complete genomemembrane protein involved in the export of O-antigen and teichoic acid8e-1479
NC_016641:1639356:1646193164619316479981806Paenibacillus terrae HPL-003 chromosome, complete genomepolysaccharide biosynthesis protein9e-1479
NC_012778:688621:6886216886216901981578Eubacterium eligens ATCC 27750, complete genomestage V sporulation protein B3e-1377.4
NC_007929:473500:4927814927814944271647Lactobacillus salivarius subsp. salivarius UCC118, complete genomeExport protein for polysaccharides and teichoic acids5e-1376.3
NC_017167:129988:1567691567691584631695Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1polysaccharide biosynthesis protein7e-1375.9
NC_011969:1816746:1816746181674618183801635Bacillus cereus Q1 chromosome, complete genomepolysaccharide biosynthesis family protein3e-1273.6
NC_016779:1688946:1688946168894616905801635Bacillus cereus F837/76 chromosome, complete genomeMembrane protein involved in the export of O- antigen, teichoic acid lipoteichoic acids4e-1273.6
NC_004193:2342528:2344769234476923463881620Oceanobacillus iheyensis HTE831, complete genomespore cortex protein3e-1170.5
NC_014727:1537183:1537183153718315388021620Lactobacillus delbrueckii subsp. bulgaricus ND02 chromosome,mop superfamily multidrug/oligosaccharidyl-lipid/polysaccharide flippase transporter5e-1169.7
NC_006270:1535770:1551974155197415533141341Bacillus licheniformis ATCC 14580, complete genomePolysaccharide biosynthesis protein1e-1068.2
NC_006322:1536426:1552834155283415541741341Bacillus licheniformis ATCC 14580, complete genomeYkvU1e-1068.2
NC_013504:447891:4673194673194689771659Lactobacillus johnsonii FI9785 chromosome, complete genomeputative export protein for polysaccharides4e-1066.6
NC_017342:1462297:1476207147620714778681662Staphylococcus aureus subsp. aureus TCH60 chromosome, completepolysaccharide biosynthesis protein5e-1066.2
NC_002952:1917999:1920745192074519224061662Staphylococcus aureus subsp. aureus MRSA252, complete genomeputative polysaccharide biosynthesis protein5e-1066.2
NC_008530:469802:4892494892494909071659Lactobacillus gasseri ATCC 33323, complete genomePolysaccharide transport membrane protein8e-1065.5
NC_016928:1843597:1846814184681418484751662Staphylococcus aureus subsp. aureus M013 chromosome, completehypothetical protein1e-0965.1
NC_016941:1774000:1775209177520917768701662Staphylococcus aureus subsp. aureus MSHR1132, complete genomeputative polysaccharide biosynthesis protein1e-0965.1
NC_007793:1871165:1874455187445518761161662Staphylococcus aureus subsp. aureus USA300, complete genomepolysaccharide biosynthesis protein1e-0964.7
NC_007795:1774725:1778129177812917797901662Staphylococcus aureus subsp. aureus NCTC 8325, complete genomepolysaccharide biosynthesis protein, putative1e-0964.7
NC_002758:1880323:1883421188342118850821662Staphylococcus aureus subsp. aureus Mu50, complete genomespore cortex protein homolog1e-0964.7
NC_017338:1830790:1831921183192118335821662Staphylococcus aureus subsp. aureus JKD6159 chromosome, completeputative polysaccharide biosynthesis protein1e-0964.7
NC_017337:1829840:1832869183286918345301662Staphylococcus aureus subsp. aureus ED133 chromosome, completepolysaccharide transport protein1e-0964.7
NC_007622:1751500:1753003175300317546641662Staphylococcus aureus RF122, complete genomeprobable polysaccharide transport protein1e-0964.7
NC_010382:3783879:3804780380478038062191440Lysinibacillus sphaericus C3-41, complete genomestage V sporulation protein B2e-0964.7
NC_014724:1731238:1731238173123817328841647Lactobacillus amylovorus GRL 1112 chromosome, complete genomeputative polysaccharide transporter2e-0964.7
NC_002953:1819411:1822644182264418243051662Staphylococcus aureus subsp. aureus MSSA476, complete genomeputative polysaccharide biosynthesis protein2e-0964.7
NC_003923:1841500:1843308184330818449691662Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein2e-0964.7
NC_009782:1881722:1884820188482018864811662Staphylococcus aureus subsp. aureus Mu3, complete genomespore cortex protein homolog1e-0964.7
NC_002951:1848684:1852144185214418538051662Staphylococcus aureus subsp. aureus COL, complete genomepolysaccharide biosynthesis protein1e-0964.7
NC_017351:1869287:1872032187203218736931662Staphylococcus aureus subsp. aureus 11819-97 chromosome, completematE family protein1e-0964.7
NC_017347:1852500:1854379185437918560401662Staphylococcus aureus subsp. aureus T0131 chromosome, completePolysaccharide biosynthesis protein1e-0964.7
NC_017343:1748620:1751718175171817533791662Staphylococcus aureus subsp. aureus ECT-R 2, complete genomematE family protein1e-0964.7
NC_017341:1851972:1855225185522518568861662Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,putative polysaccharide biosynthesis protein1e-0964.7
NC_016912:1732354:1735758173575817374191662Staphylococcus aureus subsp. aureus VC40 chromosome, completepolysaccharide biosynthesis protein1e-0964.7
NC_009641:1833000:1834985183498518366461662Staphylococcus aureus subsp. aureus str. Newman chromosome,polysaccharide biosynthesis protein1e-0964.7
NC_009632:1927372:1928503192850319301641662Staphylococcus aureus subsp. aureus JH1 chromosome, completepolysaccharide biosynthesis protein1e-0964.7
NC_009487:1925645:1928629192862919302901662Staphylococcus aureus subsp. aureus JH9 chromosome, completepolysaccharide biosynthesis protein1e-0964.7
NC_010079:1871915:1875205187520518768661662Staphylococcus aureus subsp. aureus USA300_TCH1516, completepolysaccharide biosynthesis protein1e-0964.7
NC_002745:1804000:1805507180550718071681662Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein1e-0964.7
NC_013450:1825010:1828108182810818297691662Staphylococcus aureus subsp. aureus ED98, complete genomepolysaccharide biosynthesis protein2e-0964.3
NC_005362:550823:5702505702505719081659Lactobacillus johnsonii NCC 533, complete genomeexport protein for polysaccharides and teichoic acids8e-0962.4
NC_007168:1167454:1189191118919111908281638Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein4e-0756.6
NC_020410:1301500:1313718131371813150581341Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completespore membrane protein involved in germination3e-0653.5
NC_014657:1193985:1213028121302812145721545Caldicellulosiruptor owensensis OL chromosome, complete genomepolysaccharide biosynthesis protein3e-0653.5
NC_007576:1564739:1586862158686215884601599Lactobacillus sakei subsp. sakei 23K, complete genomePutative drug:Na(+) antiporter (drug efflux pump)6e-0652.8
NC_015214:1700000:1700007170000717015871581Lactobacillus acidophilus 30SC chromosome, complete genomepolysaccharide transporter9e-0652.4