Pre_GI: BLASTP Hits

Some Help

Query: NC_010723:223935:232334 Clostridium botulinum E3 str. Alaska E43, complete genome

Start: 232334, End: 232846, Length: 513

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was probably isolated from salmon eggs associated with a foodborne case of botulism in Alaska, however the exact details are not available. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010674:222016:230402230402230914513Clostridium botulinum B str. Eklund 17B, complete genometetracycline resistance protein9e-90328
NC_009617:163466:173123173123173635513Clostridium beijerinckii NCIMB 8052 chromosome, complete genomehypothetical protein8e-69259
NC_020291:166500:174662174662175174513Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeputative RNA-binding protein6e-61233
NC_008262:2598920:263767226376722638181510Clostridium perfringens SM101, complete genomehypothetical protein2e-52204
NC_021182:4557608:459511145951114595623513Clostridium pasteurianum BC1, complete genomeputative RNA-binding protein containing a PIN domain1e-48192
NC_014393:4482896:452126545212654521774510Clostridium cellulovorans 743B chromosome, complete genomehypothetical protein4e-48190
NC_015425:198315:220995220995221504510Clostridium botulinum BKT015925 chromosome, complete genomehypothetical protein9e-48189
NC_008593:196257:216323216323216829507Clostridium novyi NT, complete genomehypothetical protein8e-47186
NC_009495:3688138:372609537260953726604510Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein1e-42172
NC_009698:3553365:359919335991933599702510Clostridium botulinum A str. Hall chromosome, complete genomehypothetical protein1e-42172
NC_012563:3956500:399402139940213994530510Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein2e-42171
NC_010516:3759136:379709237970923797601510Clostridium botulinum B1 str. Okra, complete genomehypothetical protein2e-42171
NC_010520:3788702:382669338266933827202510Clostridium botulinum A3 str. Loch Maree, complete genomehypothetical protein3e-42171
NC_017295:3250451:328811332881133288631519Clostridium acetobutylicum EA 2018 chromosome, complete genomehypothetical protein3e-38157
NC_003030:3251941:328885632888563289374519Clostridium acetobutylicum ATCC 824, complete genomeUncharacterized conserved protein, YACP B.subtilis ortholog3e-38157
NC_015687:3252233:329048332904833291001519Clostridium acetobutylicum DSM 1731 chromosome, complete genomehypothetical protein3e-38157
NC_015913:1491393:152089915208991521414516Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomehypothetical protein6e-35146
NC_017294:1457262:148728914872891487840552Candidatus Arthromitus sp. SFB-mouse-Yit, complete genometetracycline resistance protein6e-35146
NC_009633:4563877:459714545971454597654510Alkaliphilus metalliredigens QYMF chromosome, complete genomehypothetical protein8e-30129
NC_015958:2251619:231292123129212313427507Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomehypothetical protein5e-28123
NC_014220:2265882:227876822787682279283516Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomeprotein of unknown function DUF9011e-26119
NC_015555:327562:334667334667335161495Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeprotein of unknown function DUF9011e-26118
NC_014410:403776:410852410852411346495Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,protein of unknown function DUF9014e-26117
NC_019970:336472:364354364354364848495Thermoanaerobacterium thermosaccharolyticum M0795, complete genomeputative RNA-binding protein containing a PIN domain4e-26117
NC_010320:881351:886288886288886782495Thermoanaerobacter sp. X514 chromosome, complete genomehypothetical protein3e-26117
NC_010321:393000:400357400357400851495Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completehypothetical protein3e-26117
NC_014964:388458:395761395761396267507Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completehypothetical protein3e-26117
NC_013316:81969:861638616386690528Clostridium difficile R20291, complete genomehypothetical protein1e-24112
NC_014392:1935130:195110319511031951609507Caldicellulosiruptor obsidiansis OB47 chromosome, complete genomehypothetical protein3e-23107
NC_004193:119737:122295122295122804510Oceanobacillus iheyensis HTE831, complete genomehypothetical protein2e-22104
NC_014171:109280:109280109280109792513Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein3e-22104
NC_014833:3268102:3268102326810232706782577Ruminococcus albus 7 chromosome, complete genomesmall GTP-binding protein3e-22104
NC_014652:757381:775227775227775733507Caldicellulosiruptor hydrothermalis 108 chromosome, completehypothetical protein4e-22103
NC_017208:108134:111331111331111843513Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeputative cytoplasmic protein4e-22103
NC_010718:193231:198860198860199372513Natranaerobius thermophilus JW/NM-WN-LF, complete genomeprotein of unknown function DUF9011e-2099
NC_013893:2406893:242494724249472425474528Staphylococcus lugdunensis HKU09-01 chromosome, complete genomeHypothetical protein DUF901, C-terminal domain of ribosome protection-type Tc-resistance proteins2e-2098.2
NC_010382:4479464:448298344829834483495513Lysinibacillus sphaericus C3-41, complete genomehypothetical protein3e-2097.8
NC_010424:214640:218622218622219128507Candidatus Desulforudis audaxviator MP104C, complete genomeprotein of unknown function DUF9012e-1995.1
NC_012470:258287:261831261831262349519Streptococcus equi subsp. zooepidemicus, complete genomehypothetical protein1e-1892.8
NC_017342:2758157:277871627787162779240525Staphylococcus aureus subsp. aureus TCH60 chromosome, completehypothetical protein1e-1892
NC_002952:582365:584916584916585440525Staphylococcus aureus subsp. aureus MRSA252, complete genomehypothetical protein1e-1892
NC_016941:549373:552555552555553079525Staphylococcus aureus subsp. aureus MSHR1132, complete genomehypothetical protein2e-1891.7
NC_002951:596000:601073601073601597525Staphylococcus aureus subsp. aureus COL, complete genomehypothetical protein5e-1890.5
NC_002953:561740:562898562898563422525Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein5e-1890.5
NC_010079:575123:580182580182580706525Staphylococcus aureus subsp. aureus USA300_TCH1516, completehypothetical protein5e-1890.5
NC_003923:559208:564267564267564791525Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein5e-1890.5
NC_007622:537195:542255542255542779525Staphylococcus aureus RF122, complete genomehypothetical protein5e-1890.5
NC_007795:511186:516245516245516769525Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehypothetical protein5e-1890.5
NC_007793:574580:579639579639580163525Staphylococcus aureus subsp. aureus USA300, complete genomehypothetical protein5e-1890.5
NC_009641:565103:570162570162570686525Staphylococcus aureus subsp. aureus str. Newman chromosome,hypothetical protein5e-1890.5
NC_016912:511182:516241516241516765525Staphylococcus aureus subsp. aureus VC40 chromosome, completehypothetical protein5e-1890.5
NC_016928:561138:563689563689564213525Staphylococcus aureus subsp. aureus M013 chromosome, completehypothetical protein5e-1890.5
NC_017337:580850:585909585909586433525Staphylococcus aureus subsp. aureus ED133 chromosome, completehypothetical protein5e-1890.5
NC_017341:591952:593110593110593634525Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,hypothetical protein5e-1890.5
NC_017347:586629:589180589180589704525Staphylococcus aureus subsp. aureus T0131 chromosome, completehypothetical protein5e-1890.5
NC_017351:566717:571776571776572300525Staphylococcus aureus subsp. aureus 11819-97 chromosome, completeyacP-like NYN domain protein5e-1890.5
NC_002745:572959:573705573705574229525Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein5e-1890.1
NC_009782:596847:599398599398599922525Staphylococcus aureus subsp. aureus Mu3, complete genomehypothetical protein5e-1890.1
NC_002758:592892:597951597951598475525Staphylococcus aureus subsp. aureus Mu50, complete genomehypothetical protein5e-1890.1
NC_009487:609170:614229614229614753525Staphylococcus aureus subsp. aureus JH9 chromosome, completehypothetical protein5e-1890.1
NC_009632:609046:614105614105614629525Staphylococcus aureus subsp. aureus JH1 chromosome, completehypothetical protein5e-1890.1
NC_020164:2219612:224402422440242244551528Staphylococcus warneri SG1, complete genomehypothetical protein2e-1788.2
NC_004461:277291:295575295575296102528Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein6e-1787
NC_002976:177282:179827179827180354528Staphylococcus epidermidis RP62A, complete genomehypothetical protein6e-1787
NC_017338:556319:557477557477558001525Staphylococcus aureus subsp. aureus JKD6159 chromosome, completehypothetical protein9e-1786.3
NC_012121:198480:199233199233199757525Staphylococcus carnosus subsp. carnosus TM300, complete genomehypothetical protein3e-1374.7