Pre_GI: BLASTN Hits

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Query: NC_010674:3141228 Clostridium botulinum B str. Eklund 17B, complete genome

Start: 3141228, End: 3164946, Length: 23719

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum B str. Eklund 17B is a nonproteolytic botulism neurotoxin B strain. This strain was isolated from marine sediments taken off the coast of Washington, USA and was not associated with botulism. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_020291:5641444*5641444566381622373Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome01059BLASTN svgBLASTP svg
NC_010723:62292862292864247719550Clostridium botulinum E3 str. Alaska E43, complete genome0957BLASTN svgBLASTP svg
NC_010674:65859665859667712118526Clostridium botulinum B str. Eklund 17B, complete genome0886BLASTN svgBLASTP svg
NC_008593:21367592136759215512718369Clostridium novyi NT, complete genome1e-134488BLASTN svgBLASTP svg
NC_008593:555463*55546357939123929Clostridium novyi NT, complete genome7e-75289BLASTN svgBLASTP svg
NC_004557:363628*36362838772724100Clostridium tetani E88, complete genome1e-73285BLASTN svgBLASTP svg
NC_003454:249304*24930426978820485Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete2e-62248BLASTN svgBLASTP svg
NC_014328:4249032*4249032426897819947Clostridium ljungdahlii ATCC 49587 chromosome, complete genome5e-57230BLASTN svgBLASTP svg
NC_010520:35800003580000360470824709Clostridium botulinum A3 str. Loch Maree, complete genome3e-52214BLASTN svgBLASTP svg
NC_012563:37298173729817376659036774Clostridium botulinum A2 str. Kyoto, complete genome1e-48202BLASTN svgBLASTP svg
NC_004557:25524182552418257431921902Clostridium tetani E88, complete genome4e-39170BLASTN svgBLASTP svg
NC_008593:1917118*1917118196528648169Clostridium novyi NT, complete genome2e-32149BLASTN svgBLASTP svg
NC_014614:757381*75738178080323423Clostridium sticklandii, complete genome1e-30143BLASTN svgBLASTP svg
NC_015275:34073583407358344643139074Clostridium lentocellum DSM 5427 chromosome, complete genome6e-29137BLASTN svgBLASTP svg
NC_019908:22479562247956226865220697Brachyspira pilosicoli P43/6/78 chromosome, complete genome5e-23117BLASTN svgBLASTP svg
NC_018604:30595730595735100445048Brachyspira pilosicoli WesB complete genome1e-20109BLASTN svgBLASTP svg
NC_014330:95250095250097205919560Brachyspira pilosicoli 95/1000 chromosome, complete genome1e-20109BLASTN svgBLASTP svg
NC_014471:1841171*1841171187799936829Ignisphaera aggregans DSM 17230 chromosome, complete genome8e-19103BLASTN svgBLASTP svg
NC_019970:1991944*1991944200962917686Thermoanaerobacterium thermosaccharolyticum M0795, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_010003:10529971052997107805425058Petrotoga mobilis SJ95, complete genome5e-1797.6BLASTN svgBLASTP svg
NC_010718:2116889*2116889213584318955Natranaerobius thermophilus JW/NM-WN-LF, complete genome8e-1693.7BLASTN svgBLASTP svg
NC_015707:1911431*1911431193927027840Thermotoga thermarum DSM 5069 chromosome, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_015167:2415604*2415604244614330540Cellulophaga lytica DSM 7489 chromosome, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_010336:213148*21314825031237165Francisella philomiragia subsp. philomiragia ATCC 25017, complete2e-1385.7BLASTN svgBLASTP svg
NC_020291:64267046426704645309926396Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome8e-1383.8BLASTN svgBLASTP svg
NC_007633:253143*25314327396420822Mycoplasma capricolum subsp. capricolum ATCC 27343, complete5e-1177.8BLASTN svgBLASTP svg
NC_021182:14735351473535149659923065Clostridium pasteurianum BC1, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_014751:302152*30215232009917948Mycoplasma leachii PG50 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_009850:1862602*1862602190488342282Arcobacter butzleri RM4018, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_009465:90000*9000013018540186Candidatus Vesicomyosocius okutanii HA, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_013192:1886337*1886337191224425908Leptotrichia buccalis DSM 1135, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_013790:485468*48546851894933482Methanobrevibacter ruminantium M1 chromosome, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_014150:2088012*2088012212109933088Brachyspira murdochii DSM 12563 chromosome, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_015275:521436*52143655362332188Clostridium lentocellum DSM 5427 chromosome, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_015638:429913*42991345655126639Lacinutrix sp. 5H-3-7-4 chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_011999:558057*55805758118523129Macrococcus caseolyticus JCSC5402, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_014166:29596882959688298355023863Arcobacter nitrofigilis DSM 7299 chromosome, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_014209:78753578753581009922565Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,5e-0867.9BLASTN svgBLASTP svg
NC_015474:1432065*1432065145759325529Pyrococcus sp. NA2 chromosome, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_020291:18718461871846189284621001Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome5e-0867.9BLASTN svgBLASTP svg
NC_014964:16085751608575163560427030Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, complete2e-0765.9BLASTN svgBLASTP svg
NC_013921:75580075580077917523376Thermoanaerobacter italicus Ab9 chromosome, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_007984:22103022103024292321894Baumannia cicadellinicola str. Hc (Homalodisca coagulata), complete2e-0765.9BLASTN svgBLASTP svg
NC_014393:12210001221000124039419395Clostridium cellulovorans 743B chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_014393:36509573650957366964218686Clostridium cellulovorans 743B chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_014721:508000*50800053060122602Caldicellulosiruptor kristjanssonii 177R1B chromosome, complete7e-0763.9BLASTN svgBLASTP svg
NC_015949:1957185*1957185197800220818Caldicellulosiruptor lactoaceticus 6A chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_015555:863173*86317388705323881Thermoanaerobacterium xylanolyticum LX-11 chromosome, complete3e-0661.9BLASTN svgBLASTP svg
NC_013171:636293*63629365943323141Anaerococcus prevotii DSM 20548, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_009802:1570215*1570215159609925885Campylobacter concisus 13826, complete genome3e-0661.9BLASTN svgBLASTP svg