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Query: NC_010674:2930259 Clostridium botulinum B str. Eklund 17B, complete genome

Start: 2930259, End: 2949576, Length: 19318

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum B str. Eklund 17B is a nonproteolytic botulism neurotoxin B strain. This strain was isolated from marine sediments taken off the coast of Washington, USA and was not associated with botulism. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010723:27351962735196275388618691Clostridium botulinum E3 str. Alaska E43, complete genome010420BLASTN svgBLASTP svg
NC_003366:19018981901898192440722510Clostridium perfringens str. 13, complete genome01189BLASTN svgBLASTP svg
NC_008262:17959141795914181428418371Clostridium perfringens SM101, complete genome01170BLASTN svgBLASTP svg
NC_008261:21172072117207214023523029Clostridium perfringens ATCC 13124, complete genome01166BLASTN svgBLASTP svg
NC_012563:29791472979147300249023344Clostridium botulinum A2 str. Kyoto, complete genome6e-155555BLASTN svgBLASTP svg
NC_008593:84129184129186462123331Clostridium novyi NT, complete genome2e-142513BLASTN svgBLASTP svg
NC_013192:81585481585483809922246Leptotrichia buccalis DSM 1135, complete genome9e-83315BLASTN svgBLASTP svg
NC_007681:1300068*1300068132484524778Methanosphaera stadtmanae DSM 3091, complete genome2e-37165BLASTN svgBLASTP svg
NC_003413:181525*18152520476123237Pyrococcus furiosus DSM 3638, complete genome5e-32147BLASTN svgBLASTP svg
NC_000909:201000*20100022113320134Methanocaldococcus jannaschii DSM 2661, complete genome3e-27131BLASTN svgBLASTP svg
NC_015216:40565740565742827422618Methanobacterium sp. AL-21 chromosome, complete genome1e-26129BLASTN svgBLASTP svg
NC_015474:723553*72355378401560463Pyrococcus sp. NA2 chromosome, complete genome2e-25125BLASTN svgBLASTP svg
NC_013741:1390823*1390823141480423982Archaeoglobus profundus DSM 5631, complete genome4e-23117BLASTN svgBLASTP svg
NC_014222:18687618687620859921724Methanococcus voltae A3 chromosome, complete genome2e-22115BLASTN svgBLASTP svg
NC_000868:1730820*1730820175956428745Pyrococcus abyssi GE5, complete genome1e-20109BLASTN svgBLASTP svg
NC_012883:1603744*1603744162651022767Thermococcus sibiricus MM 739, complete genome2e-19105BLASTN svgBLASTP svg
NC_014122:39385639385641638122526Methanocaldococcus infernus ME chromosome, complete genome4e-1797.6BLASTN svgBLASTP svg
NC_003106:1435295*1435295145619720903Sulfolobus tokodaii str. 7, complete genome6e-1693.7BLASTN svgBLASTP svg
NC_014410:51711*517119003438324Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,6e-1693.7BLASTN svgBLASTP svg
NC_015847:1119666*1119666114458724922Methanococcus maripaludis XI chromosome, complete genome6e-1693.7BLASTN svgBLASTP svg
NC_019970:35985359857648740503Thermoanaerobacterium thermosaccharolyticum M0795, complete genome6e-1693.7BLASTN svgBLASTP svg
NC_007907:52974775297477532099523519Desulfitobacterium hafniense Y51, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_005791:1028500*1028500105154523046Methanococcus maripaludis S2, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_009975:1500978*1500978152309922122Methanococcus maripaludis C6, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_010520:28074292807429283431926891Clostridium botulinum A3 str. Loch Maree, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_013926:1205443*1205443122506719625Aciduliprofundum boonei T469 chromosome, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_015574:2057602*2057602208210924508Methanobacterium sp. SWAN-1 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_015562:62700062700064529218293Methanotorris igneus Kol 5 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_010674:14965001496500152566029161Clostridium botulinum B str. Eklund 17B, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_007644:13527941352794137309920306Moorella thermoacetica ATCC 39073, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_009135:494949*49494951848723539Methanococcus maripaludis C5, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_013156:431795*43179546884337049Methanocaldococcus fervens AG86, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_006270:40140004014000403670422705Bacillus licheniformis ATCC 14580, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_018876:24038922403892243268228791Methanolobus psychrophilus R15 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_014209:2257316*2257316228561028295Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,6e-1073.8BLASTN svgBLASTP svg
NC_013921:23759002375900240259926700Thermoanaerobacter italicus Ab9 chromosome, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_014720:1737574*1737574175691719344Caldicellulosiruptor kronotskyensis 2002 chromosome, complete2e-0971.9BLASTN svgBLASTP svg
NC_015435:310406*31040632990319498Metallosphaera cuprina Ar-4 chromosome, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_015958:1465631*1465631149575430124Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014964:1353939*1353939137489920961Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, complete4e-0867.9BLASTN svgBLASTP svg
NC_014538:1125000*1125000114695821959Thermoanaerobacter sp. X513 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014209:1363151*1363151138961426464Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,4e-0867.9BLASTN svgBLASTP svg
NC_013921:1344000*1344000136970025701Thermoanaerobacter italicus Ab9 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_009848:1494253*1494253151878524533Bacillus pumilus SAFR-032, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_010674:18229631822963184273319771Clostridium botulinum B str. Eklund 17B, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_019977:828427*82842785333324907Methanomethylovorans hollandica DSM 15978, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_005877:509877*50987753290123025Picrophilus torridus DSM 9790, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_020134:27725002772500279254620047Clostridium stercorarium subsp. stercorarium DSM 8532, complete2e-0661.9BLASTN svgBLASTP svg
NC_009922:2721343*2721343276393542593Alkaliphilus oremlandii OhILAs, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_013407:1610221*1610221163174921529Methanocaldococcus vulcanius M7, complete genome9e-0660BLASTN svgBLASTP svg
NC_008346:1047500*1047500106959922100Syntrophomonas wolfei subsp. wolfei str. Goettingen, complete9e-0660BLASTN svgBLASTP svg