Pre_GI: BLASTN Hits

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Query: NC_010674:1170264 Clostridium botulinum B str. Eklund 17B, complete genome

Start: 1170264, End: 1192433, Length: 22170

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum B str. Eklund 17B is a nonproteolytic botulism neurotoxin B strain. This strain was isolated from marine sediments taken off the coast of Washington, USA and was not associated with botulism. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010184:44256764425676444871923044Bacillus weihenstephanensis KBAB4, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_012225:47800478008109933300Brachyspira hyodysenteriae WA1, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_014150:29940002994000301678522786Brachyspira murdochii DSM 12563 chromosome, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_014330:76823276823281309944868Brachyspira pilosicoli 95/1000 chromosome, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_019908:24015772401577244617744601Brachyspira pilosicoli P43/6/78 chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_018604:22535392253539227800524467Brachyspira pilosicoli WesB complete genome2e-1385.7BLASTN svgBLASTP svg
NC_016012:805680*80568082784122162Candidatus Arthromitus sp. SFB-rat-Yit, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_016024:1764516*1764516180484640331Candidatus Chloracidobacterium thermophilum B chromosome chromosome2e-0765.9BLASTN svgBLASTP svg
NC_003030:3763054*3763054378965126598Clostridium acetobutylicum ATCC 824, complete genome3e-18101BLASTN svgBLASTP svg
NC_015687:3766000*3766000379114625147Clostridium acetobutylicum DSM 1731 chromosome, complete genome3e-18101BLASTN svgBLASTP svg
NC_018664:1699618*1699618171859918982Clostridium acidurici 9a chromosome, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_012563:32881243288124330917721054Clostridium botulinum A2 str. Kyoto, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_012563:4101000*4101000412265321654Clostridium botulinum A2 str. Kyoto, complete genome1e-45192BLASTN svgBLASTP svg
NC_010520:3938490*3938490397609937610Clostridium botulinum A3 str. Loch Maree, complete genome2e-37165BLASTN svgBLASTP svg
NC_010674:61596361596363966223700Clostridium botulinum B str. Eklund 17B, complete genome2e-28135BLASTN svgBLASTP svg
NC_010516:3903867*3903867395059846732Clostridium botulinum B1 str. Okra, complete genome4e-48200BLASTN svgBLASTP svg
NC_010723:57525457525460199426741Clostridium botulinum E3 str. Alaska E43, complete genome2e-28135BLASTN svgBLASTP svg
NC_010723:1133163*1133163115110717945Clostridium botulinum E3 str. Alaska E43, complete genome014470BLASTN svgBLASTP svg
NC_014393:49881274988127501003921913Clostridium cellulovorans 743B chromosome, complete genome1e-36163BLASTN svgBLASTP svg
NC_013316:1225797*1225797124983024034Clostridium difficile R20291, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_015275:32999233299923332126821346Clostridium lentocellum DSM 5427 chromosome, complete genome1e-29139BLASTN svgBLASTP svg
NC_014328:4546390*4546390457009623707Clostridium ljungdahlii ATCC 49587 chromosome, complete genome5e-29137BLASTN svgBLASTP svg
NC_008593:37456*374566080623351Clostridium novyi NT, complete genome5e-23117BLASTN svgBLASTP svg
NC_021182:48824944882494490859926106Clostridium pasteurianum BC1, complete genome2e-38168BLASTN svgBLASTP svg
NC_021182:40112940112942526224134Clostridium pasteurianum BC1, complete genome1e-29139BLASTN svgBLASTP svg
NC_010001:18060001806000182359917600Clostridium phytofermentans ISDg, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_020291:12668851266885130737240488Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome01007BLASTN svgBLASTP svg
NC_015737:20502192050219206809917881Clostridium sp. SY8519, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_004557:81362*8136210417722816Clostridium tetani E88, complete genome3e-27131BLASTN svgBLASTP svg
NC_012778:17786541778654180274524092Eubacterium eligens ATCC 27750, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_010336:1468760*1468760149027221513Francisella philomiragia subsp. philomiragia ATCC 25017, complete4e-0867.9BLASTN svgBLASTP svg
NC_009515:705911*70591173209126181Methanobrevibacter smithii ATCC 35061, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_007681:1007375*1007375105211944745Methanosphaera stadtmanae DSM 3091, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_014964:1309845*1309845133261422770Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, complete3e-0661.9BLASTN svgBLASTP svg
NC_004344:672550*67255070049927950Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,1e-1179.8BLASTN svgBLASTP svg